What is Ceftriaxone 1g used for?

Ceftriaxone is a 3rd generation cephalosporin antibiotic with a broad spectrum of activity against many Gram-negative bacteria and significant activity against Strep strains. Pneumoniae and Viridans Strep. So what is Ceftriaxone 1g used for and how is it used?

Ceftriaxone 1g drug is indicated for the treatment of serious infections caused by microorganisms sensitive to Ceftriaxone including:
Meningitis, bacteremia. Infections of the ear, nose and throat, lower respiratory tract. Urinary tract infection - kidney. Gonorrhea, typhoid, syphilis. Infections of bones, joints, skin, soft tissues and wounds. Abdominal infections (peritonitis, biliary tract infections, gastro-intestinal tract infections). Prophylaxis of infection in surgical, endoscopic interventions.

Ceftriaxone 1g is contraindicated in the following cases:
Patients with hypersensitivity to Cephalosporins, a history of anaphylactic reactions to penicillin. Ceftriaxone should not be used concurrently with calcium or calcium-containing products. Hypersensitivity to Lidocaine (if Lidocaine is used as a solvent).

Common effects: gastrointestinal: diarrhea - skin: itching, rash. Rare effects: systemic: fever, phlebitis, edema - blood: eosinophilia, thrombocytopenia, leukopenia. Rare effects: systemic: headache, dizziness, anaphylaxis - blood: anemia, coagulopathy - gastrointestinal: pseudomembranous colitis. Inform your doctor immediately of any unwanted effects encountered while using the drug.

Dosage : As prescribed by the doctor. Intramuscular or intravenous injection.
Adults and children over 40kg
1–2g/day, injected once or divided equally into 2 times. In severe cases, up to 4g/day can be used. For intraoperative prophylaxis: intramuscular or intravenous as a single dose of 1g 30–120 minutes before surgery. Children
50-75mg/kg/day, injected once or divided equally into 2 times. The total dose should not exceed 2g per day. Newborns
Dosage 50mg/kg/day. Meningitis: the starting dose is 100mg/kg (not to exceed 4 grams). Then total daily dose: 100mg/kg, injected once a day for 7-14 days. Usually treatment with Ceftriaxone should continue for a minimum of 2 days after signs and symptoms disappear.
How to use : It is recommended to use freshly prepared Ceftriaxone solutions.
Intramuscular: dissolve 1g of Ceftriaxone in 3.5ml of 1% Lidocaine solution. Intravenous injection: Dissolve 1g of Ceftriaxone in 10ml of sterile distilled water for injection. Injection time: 2-4 minutes. Infusion: Dissolve 2g of Ceftriaxone in 40ml of calcium-free infusion solutions such as: 0.9% Sodium chloride solution, 5% Glucose solution, 10% Glucose solution, or 0.45% Sodium chloride solution and 2.5% Glucose solution. . The duration of intravenous infusion is at least 30 minutes.

For people who are allergic to Penicillin may be cross-allergic to Ceftriaxone. Discontinue use in case of an allergic reaction to Ceftriaxone. For patients with impaired liver and kidney function, the dose must be carefully considered, should not exceed 2g/day. The drug should be avoided in neonates with hyperbilirubinemia, especially premature infants. Use caution when administering Ceftriaxone to pregnant or lactating women. Ceftriaxone 1g is indicated for the treatment of serious infections caused by microorganisms sensitive to Ceftriaxone. To ensure effective use and avoid side effects, you need to follow the instructions of your doctor and medical staff.
Follow Vinmec International General Hospital website to get more health, nutrition and beauty information to protect the health of yourself and your loved ones in your family.