What is Gentrisone and how is it used?


Gentrisone is a topical cream used quite a lot in skin diseases. You probably don't know what gentrisone is and what specifically it treats. The use of gentrisone in the treatment of dermatological diseases as well as some frequently asked questions will be presented in this article.

1. What is Gentrisone?


What is gentrisone, and what ingredients does it have? Gentrisone is a topical cream containing the active ingredients Betamethasone dipropionate, Clotrimazole and Gentamicin Sulphate and other excipients.
Betamethasone dipropionate ingredient in the cream has the effect of inhibiting the synthesis of some inflammatory mediators such as cytokines, prostaglandins, leukotrienes; reduces histamine release from mast cells. Clotrimazole inhibits fungal growth. Specifically, Clotrimazole exerts its effects mainly by damaging the permeable barrier in the cytoplasmic membrane of fungi, inhibiting ergosterol biosynthesis. Gentamicin sulphate is an antibiotic of the group that inhibits the growth of bacteria, with broad-spectrum activity against Gram (+) and Gram (-) bacteria. Gentamicin sulphate irreversibly inhibits bacterial protein synthesis. Drugs diffuse through channels in the outer membrane, after which the drug is actively transported across the cell membrane to enter the cytoplasm. After entering the cytoplasm, aminosides will bind to the 30S ribosome, inhibiting protein synthesis in such ways as: interfering with the initiation complex of peptide chain formation, causing misreading of the mRNA code, distorting the amino acids in the peptide chain, produce proteins that have no function on bacterial cells and are toxic; Prevents ribosomal translocation of the mRNA. These effects can occur at the same time, causing irreversible inhibition of protein synthesis, causing the bacteria to be destroyed.

2. What disease does Gentrisone treat?


What disease Gentrisone treats is what people care about. Gentrisone is used for the treatment of bacterial infections, relief of itching, burning, cracking and scaling associated with the skin of the feet, itchy pruritus and ringworm, treatment of ringworm, treatment of itchy skin, spontaneous reactions immunity, foot fungus treatment, oral thrush prevention, chronic inflammation, bacterial infection, vulvovaginitis and other conditions.
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3. Contraindications of Gentrisone


Hypersensitivity to Gentrisone is a contraindication. In addition, Gentrisone should not be used if you have the following conditions:
First trimester of pregnancy Hypersensitivity Hypersensitivity to imidazole Do not give Gentrisone to children under 2 years of age unless directed by your doctor Do not use used when having diaper rash

4. Gentrisone side effects


When using Gentrisone, you may experience some unwanted effects such as:
Itching or burning Itching Irritation Irritation Burning Red Swelling Stomach pain Fever Bad-smelling discharge if using vaginal products Abdominal discomfort Vomiting if using lozenges Skin irritation Dizziness Difficulty breathing

5. Interactions with Gentrisone


The effect of Gentrisone may be changed if taken with some other drugs or supplements. Specifically, it can increase the risk of side effects, reduce the effectiveness of the drug. Gentrisone can interact with drugs such as: Aminoglycosides, Cephaloridine, Cidofovir, Cisplatin.
In addition, some health conditions can make you more susceptible to side effects from medications, for example:
Acquired immunodeficiency syndrome Alcohol use Having a history of allergies to ingredients in medicine Gentrisone Diabetes Elderly patients History of alcohol abuse Viral infections in immunocompromised people
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6. Dosage and how to use Gentrisone


Depending on your medical condition, your doctor will prescribe the drug 1-3 times per day. To achieve the desired effect of Gentrisone, you should follow these steps:
Clean the skin, dry the skin before applying the medicine Do not wash the treatment area after applying Gentrisone immediately. Avoid using other topical products on the treated area unless directed by your doctor. Apply only a thin layer to and around the injured area. If applied too much can lead to lumps. Avoid getting Gentrisone in your eyes or nose or mouth Wash your hands before and after applying Gentrisone.

7. Some frequently asked questions during the use of Gentrisone


7.1. How long does it take to take Gentrisone to improve symptoms? According to the feedback of Gentrisone users, usually, after using it for 3-7 days, the symptoms will improve.
7.2. Can I drive or operate heavy machinery while using Gentrisone? If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Gentrisone medicine then it may not be safe to drive a vehicle or operate heavy machinery. According to health experts, patients should not drink alcohol with drugs, because alcohol increases the side effect of drowsiness.
7.3. What should I do if I miss a dose? In case you miss a dose, use it as soon as you remember. If the time you remember is close to the time of your next dose, skip the missed dose and take the medicine as scheduled for your next dose. However, if you frequently forget to apply the medication, this can affect the results of your treatment. You should set an alarm or ask a loved one to remind you to take your medicine on time. When you miss too many doses, consult your doctor about your dosing regimen before continuing.
7.4. How should Gentrisone be stored? Store Gentrisone at room temperature, away from heat and direct light. Do not freeze Gentrisone unless you read the instructions in the package insert. Keep Gentrisone medicine away from children and pets.
So, do you know what is gentrisone? However, you should note that do not arbitrarily use the drug without the guidance and prescription of the doctor. When you have any skin disease, you should go to a dermatologist for timely examination and treatment.
Follow Vinmec International General Hospital website to get more health, nutrition and beauty information to protect the health of yourself and your loved ones in your family.

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Bài viết này được viết cho người đọc tại Sài Gòn, Hà Nội, Hồ Chí Minh, Phú Quốc, Nha Trang, Hạ Long, Hải Phòng, Đà Nẵng.

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