What is Rabesime 20mg?

Rabesime 20mg belongs to the class of proton pump inhibitors used in the treatment of duodenal ulcers, gastroesophageal reflux disease and Zollinger-Ellison syndrome. This is a prescription drug, so you need to use it under the guidance of your doctor.

Rabesime 20mg contains the main ingredient Rabeprazole sodium. It is used to treat duodenal ulcers, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. In addition, in the treatment regimen of Helicobacter pylori in patients with peptic ulcer disease, the drug is also indicated in combination with appropriate antibiotics to improve the effectiveness of treatment.

Rabesime 20mg is indicated in the following cases:
Active duodenal ulcer disease; ulcerative or erosive gastroesophageal reflux disease (GERD); Treatment of gastroesophageal reflux with maintenance doses; Patients with moderate to very severe gastroesophageal reflux disease; Zollinger-Ellison syndrome; Treatment of peptic ulcer disease in combination with appropriate antibiotics in the Helicobacter pylori treatment regimen. Rabesime 20mg is contraindicated in cases of:
Rabesime 20mg is contraindicated in cases of hypersensitivity to Benzimidazole, Rabeprazole sodium or any of the ingredients in the drug.

Depending on the purpose of treatment, the dose of Rabesime 20mg will be different as follows:
Peptic ulcer: Rabesime is used orally with a dose of 1 tablet/day (equivalent to 20mg/day), should be taken orally. in the morning 30 minutes before eating. Do not chew, crush or break the medicine. The majority of duodenal ulcer patients improve within 4 weeks of taking the drug. However, in some cases it may take more than a week for the ulcer to heal completely. Gastroesophageal reflux disease (GERD): The recommended dose is 1 20 mg tablet orally once a day for 4-8 weeks. Long-term treatment of gastroesophageal reflux - esophagitis maintenance: With this form of treatment, the recommended dose is usually 20 mg or 10 mg / time / day depending on the patient's current condition and response. with treatment. Moderate to very severe gastroesophageal reflux disease: For patients without esophagitis, the recommended dose is 10mg once daily. If the condition has not improved after 4 weeks, the patient should be re-diagnosed. In case the symptoms have been effectively controlled with the right nutrition, the drug can be used at a dose of 10mg / time / day. Zollinger-Ellison syndrome: Patients should begin with the recommended dose of 60 mg orally once daily. It can then be increased to 100mg, once/day or 120mg/day in 2 divided doses based on the patient's current condition and response to the drug. Combined with antibiotics in H. pylori treatment regimens: In this regimen, patients need to be treated with eradication methods. The following drugs will be combined and used for 7 days: Rabeprazole 20mg + Amoxicillin 1g + Clarithromycin 500mg] x 1 time / day. Children: Currently, there are no research results for the effectiveness of using Rabesime in children, so it is not recommended to use this drug for children. The above dosage is for reference only. The correct dosage should be based on the patient's current condition and disease progression. Therefore, you need to consult your doctor before use.

It is necessary to exclude the possibility that the patient has gastric cancer before taking the drug because Rabeprazole cos theer will mask the symptoms of the disease.
Patients on long-term drug use for more than one year should be monitored regularly.
Be careful when using Rabeprazole with other proton pump inhibitors because cross-reactivity may occur.
Drugs belonging to the proton pump inhibitor class, including Rabeprazole, can increase the risk of gastrointestinal infections such as Salmonella, Clostridium difficile, Campylobacter infections.
When used in high doses and for longer than 1 year in the elderly population may slightly increase the risk of fracture. Therefore, patients at risk of osteoporosis while taking this drug should receive care as directed, supplementing with vitamin D and calcium.
Rabeprazole sodium may decrease the effectiveness of antifungal medicines such as Itraconazole or Ketoconazole when used together. Therefore, in case of necessity, the doctor can consider and adjust the dosage of the above drugs so that it is reasonable.
In summary, the effect of Rabesime 20mg is to support the treatment of duodenal ulcers, gastroesophageal reflux disease and Zollinger-Ellison syndrome. Patients need to use the drug exactly as prescribed by the doctor to increase the effectiveness of treatment and ensure safety for health.