Stem cell therapy research project
1. Therapy development
Based on the its previous success in the development of stem cell-based management for patients with cerebral palsy and autism, VIRISG will continue to evaluate the efficacy of stem cells in various other incurable diseases, by that making Vinmec an excellent regenerative medicine center in the region. The long-term strategy is to evaluate the ability of using stem cells (UC-MSCs) as off-the-self medicine products to treat various diseases.
| Projects |
| To develop stem cell therapy for autism |
| To develop stem cell therapy for type II diabetes |
| To develop stem cell therapy for hormone deficiency |
| To develop stem cell therapy for COPD |
| To develop stem cell therapy for neurological sequelae after traumatic brain injury |
| To develop stem cell therapy for Liver Cirrhosis due to Biliary Atresia |
| To develop stem cell therapy for infertility due to Asherman’s syndrome |
| To develop stem cell therapy for ischemic stroke |
| To develop stem cell therapy for bronchopulmonary dysplasia |
| To produce stem cell-derived extracellular vesicle for skin rejuvenation |
| To develop hematopoietic stem cell transplantation for cancers, genetic diseases, and autoimmune diseases |
2. Manufacturing development
Over the implemented stem cell researches, VRISG has developed the technologies for isolation, expansion and storage of the stem cells from various sources. The next step is to establish various stem cell biobanks and manufacture off-the-self stem cell-based medicine products that can be transported into other institutions, either inside or outside of the Vinmec healthcare system, for in patient administration.
| Projects |
| Technology development for establishment of the umbilical cord, adipose and bone marrow- derived stem cell biobank |
| Technology development for manufacturing off-the-self stem cell product |
| Technology development for manufacturing off-the-self extracellular vesicle product |
| Establishment of human amniotic membrane bank for corneal membrane generation |
3. Basic research
Although translational study is the main focus of VRISG, basic research is conducted to decipher the mechanism of stem cell-based therapeutic effects in clinical settings, by that facilitates the further improvement of the developed therapies. By initiating the human induced pluripotent cell project, our long-term strategy is to produce 3D printed organoid
| Projects |
| Disease modeling by using human induced pluripotent stem cells (hiPSC) |
| To study biological characteristics of stem cells from various sources |
| To characterize stem cell-derived exosomes for clinical applications |
| Mechanistic analysis of stem cell-mediated therapeutic efficacy in autism |
| GGeneration of hiPSC-based cardiomyocyte for heart disease modelling and drug testing (tentatively) |