Ph.D, MD Nguyen Van Dinh

Nguyen Van Dinh, MD, Ph.D has more than 10 years of experience in Allergy and Clinical Immunology, specialize in asthma, allergy and clinical Immunology diseases.

Dr. Dinh Van Nguyen graduated Medical Doctor from Hanoi Medical University (HMU) in 2007 and completed the residency in Allergy and Clinical Immunology with the excellent standings (2011). He was later appointed as a lecturer at the Department of Allergy and Clinical Immunology, HMU and was awarded by AAS (Australia Awards Scholarship) for his PhD (Medicine) at Northern Clinical School, Faculty of Medicine, The University of Sydney in 2018. Dr Dinh has completed to several clinical placements at major teaching hospitals in Australia and the US. Currently, Dr Nguyen is working for Vinmec Hospital as head of Internal Medicine Department and affiliated Lecturer of College of Health Sciences, VinUniversity, Adjunct Clinical Assistant Professor, College of Medicine, Penn State, The US.

He has membership of AAAAI, EACCI, Junior Member (JM) of WAO and Asian Pacific Society of Respiratory (APSR). A member of Urticaria/Angioedema guideline panel. His main research interests are the association of HLA and severe cutaneous adverse drug reactions (SCARs). To date, Dr Nguyen has published 01 edited book, 5 book chapters 23 ISI/SCOPUS peer-reviewed papers with more than 300 citations in total, making his H-index of 9. Dr Nguyen has served as a reviewer for Pharmacogenomics and Genetics (IF 2.1), The Pharcogenomics Journal (IF 4.1), Molecular Medicine (IF 5.3) and Allergy (IF 7.3). Currently, he is the PI of a 3 year- research project entitled “Gene signatures of drug hypersensitivity in Vietnamese” funded by VinBDI. Thanks to his contribution in Allergy and Clinical Immunology, Dr Nguyen has been awarded a number of important awards internationally and locally such as “The Best Paper Award” at APACCI 2013, “The Best Article of The Year” in Asia Pacific Allergy Journal (2015-2018), Chairman’s Award of Hoc Mai Foundation, The University of Sydney (2016), WAO Travel grant (2015), AAAAI travel grant (2016) and the third place of Dang Van Ngu’s Prize for the international publication at HMU (2017),  Clinical Allergy and Immunology Assembly Award of APSR (2019) and Internal Medicine Residency Program excellent Teacher Award (Academic Year 2020-2021).

To date, Dr Nguyen has supervised successfully 4 medical students in Hanoi Medical University and 2 postgraduate student in Hanoi University of Pharmacy. 

Currently, Dr Nguyen is working for Vinmec Hospital as head of Internal Medicine Department and affiliated Assistant Professor of College of Health Sciences, VinUniversiy. 

• Principal Investigator (PI) - “Gene signatures of drug hypersensitivity in Vietnamese” funded by VinBIGDATA.

• To date, Dr Nguyen has published 01 edited book, 5 book chapters 23 ISI/SCOPUS peer-reviewed papers with more than 300 citations in total, making his H-index of 9. Currently, he is the PI of a 3 year- research project entitled “Gene signatures of drug hypersensitivity in Vietnamese” funded by VinBDI. Thanks to his contribution in Allergy and Clinical Immunology, Dr Nguyen has been awarded a number of important awards internationally and locally such as “The Best Paper Award” at APACCI 2013, “The Best Article of The Year” in Asia Pacific Allergy Journal (2015-2018), Chairman’s Award of Hoc Mai Foundation, The University of Sydney (2016), WAO Travel grant (2015), AAAAI travel grant (2016) and the third place of Dang Van Ngu’s Prize for the international publication at HMU (2017),  Clinical Allergy and Immunology Assembly Award of APSR (2019) and Internal Medicine Residency Program excellent Teacher Award (Academic Year 2020-2021).

• An overview of the role of passive immune system in drug allergy of the European Allergy Society (PAI) Editorial Board of Allergy (EAACI) with IF 4.1

• Dr Nguyen has served as a reviewer for Pharmacogenomics and Genetics (IF 2.1), The Pharcogenomics Journal (IF 4.1), Molecular Medicine (IF 5.3) and Allergy (IF 7.3)

Công bố quốc tế

1. Li, P. H., Pawankar, R., Thong, B. Y., Fok, J. S., Chantaphakul, H., Hide, M., Jindal, A. K., Kang, H. R., Abdul Latiff, A. H., Lobo, R. C. M., Munkhbayarlakh, S., Nguyen, D. V., Shyur, S. D., Zhi, Y., & Maurer, M. (2022). Epidemiology, Management, and Treatment Access of Hereditary Angioedema in the Asia Pacific Region: Outcomes From an International Survey. The journal of allergy and clinical immunology. In practice, S2213-2198(22)01334-4. Advance online publication. https://doi.org/10.1016/j.jaip.2022.12.021 (IF 11).

2. Nguyen, KH, Nguyen, QA, Tran, MH, Can, TT, Vu, MT & Vo, NS et al. Autosomal recessive hyper-IgE syndrome due to DOCK8 deficiency: An adjunctive role for omalizumab. J Cutan Immunol Allergy. 2022; 5: 222– 226. https://doi.org/10.1002/cia2.12273

3. Nguyen, P. M., Vu, D. D., Vu, K. D., Nguyen, H. T., & Nguyen, D. V. (2022). Stiff Person Syndrome: A Case Report with Sudden Onset and Coexistence of Sero-Positive Antibodies to Glutamic Acid Decarboxylase and Anti-SOX1 Antibodies. Case reports in neurology, 14(2), 237–244. https://doi.org/10.1159/000523988

4. Maurer, M.+, Magerl, M.+*, Betschel, S.*, Aberer, W., Ansotegui, I. J., Aygören-Pürsün, E., Banerji, A., Bara, N.-A., Boccon-Gibod, I., Bork, K., Bouillet, L., Boysen, H. B., Brodszki, N., Busse, P. J., Bygum, A., Caballero, T., Cancian, M., Castaldo, A., Cohn, D. M., Csuka, D., Farkas, H., Gompels, M., Gower, R., Grumach, A. S., Guidos-Fogelbach, G., Hide, M., Kang, H.-R., Kaplan, A. P., Katelaris, C., Kiani-Alikhan, S., Lei, W.-T., Lockey, R., Longhurst, H., Lumry, W. R., MacGinnitie, A., Malbran, A., Martinez Saguer, I., Matta, J J., Nast, A., Nguyen, D., Nieto-Martinez, S. A., Pawankar, R., Peter, J., Porebski, G., Prior, N., Reshef, A., Riedl, M., Ritchie, B., Sheikh, F. R., Smith, W. B., Spaeth, P. J., Stobiecki, M., Toubi, E., Varga, L. A., Weller, K., Zanichelli, A., Zhi, Y., Zuraw, B., and Craig, T.*: The international WAO/EAACI guideline for the management of hereditary angioedema – the 2021 revision and update. Allergy 2022: in press. IF: TBD (IF 2020: 13.15)

5. Maurer, M.+, Magerl, M.+*, Betschel, S.*, Aberer, W., Ansotegui, I. J., Aygören-Pürsün, E., Banerji, A., Bara, N.-A., Boccon-Gibod, I., Bork, K., Bouillet, L., Boysen, H. B., Brodszki, N., Busse, P. J., Bygum, A., Caballero, T., Cancian, M., Castaldo, A., Cohn, D. M., Csuka, D., Farkas, H., Gompels, M., Gower, R., Grumach, A. S., Guidos-Fogelbach, G., Hide, M., Kang, H.-R., Kaplan, A. P., Katelaris, C., Kiani-Alikhan, S., Lei, W.-T., Lockey, R., Longhurst, H., Lumry, W. R., MacGinnitie, A., Malbran, A., Martinez Saguer, I., Matta, J J., Nast, A., Nguyen, D., Nieto-Martinez, S. A., Pawankar, R., Peter, J., Porebski, G., Prior, N., Reshef, A., Riedl, M., Ritchie, B., Sheikh, F. R., Smith, W. B., Spaeth, P. J., Stobiecki, M., Toubi, E., Varga, L. A., Weller, K., Zanichelli, A., Zhi, Y., Zuraw, B., and Craig, T.*: The international WAO/EAACI guideline for the management of hereditary angioedema – the 2021 revision and update. World Allergy Organ. J. 2022:in press. IF: TBD (IF 2020: 4.08)

6. Tran Thu Ha Pham, Quang Binh Tran, Chi Hieu Chu, Thi Quynh Nga Do, Hoang Anh Nguyen, Dinh Van Nguyen, and Thanh Huong Phung. Allopurinol-induced severe cutaneous adverse reactions in Vietnamese: the role of HLA alleles and other risk factors. Pharmacogenomics 2022 23:5, 303-313

7. Vu, M. T., Nguyen, A. Q., Nguyen, B. D., Duong, H. T., Van Nguyen, Q., Nguyen, H. H., Phung, L. N., & Van Nguyen, D. (2021). Utility of skin testing in assessment of post-AZD1222 vaccine (AstraZeneca) allergic reactions: case series in Vietnam. Asia Pacific allergy, 11(4), e40. https://doi.org/10.5415/apallergy.2021.11.e40

8. Pham, T., Tran, Q. B., Sukasem, C., Nguyen, V. D., Chu, C. H., Do, T., Tran, N., Nguyen, H. H., & Phung, T. H. (2021). A novel nested allele-specific PCR protocol for the detection of the HLA-A*33:03, a SCAR-associated allele, in Vietnamese people. Asian Pacific journal of allergy and immunology, 10.12932/AP-201120-1000. Advance online publication. https://doi.org/10.12932/AP-201120-1000

9. Pham, T., Tran, Q. B., Sukasem, C., Nguyen, V. D., Chu, C. H., Do, T., Tran, N., & Phung, T. H. (2021). A Novel Allele-Specific PCR Protocol for the Detection of the HLA-C*03:02 Allele, a Pharmacogenetic Marker, in Vietnamese Kinh People. The application of clinical genetics, 14, 27–35. https://doi.org/10.2147/TACG.S278652

10. Tong H, Phan NVT, Nguyen TT, Nguyen DV, Vo NS, Le L. Review on Databases and Bioinformatic Approaches on Pharmacogenomics of Adverse Drug Reactions. Pharmgenomics Pers Med. 2021;14:61-75
https://doi.org/10.2147/PGPM.S290781

11. Nguyen DV, Chu HC, Vidal C, Anderson J, Nguyen NN, Quynh Do NT, Tran TL, Nguyen TN, Thu Nguyen HT, Fulton RB, van Nunen S, Fernando S. Gene expression profiling in allopurinol-induced severe cutaneous adverse reactions in Vietnamese. Pharmacogenomics. 2020 Sep;21(14):985-994. doi: 10.2217/pgs-2020-0014. Epub 2020 Sep 8. PMID: 32896208. 7.

12. Nguyen, D.V., Chu, H. C., Vidal, C., Fulton, R. B., Nguyen, N. N., Quynh Do, N. T., Tran, T. L., Nguyen, T. N., Thu Nguyen, H. T., Chu, H. H., Thanh Thuc, H. T., Minh Le, H. T., van Nunen, S., Anderson, J., & Fernando, S. L. (2021). Genetic susceptibilities and prediction modeling of carbamazepine and allopurinol-induced severe cutaneous adverse reactions in Vietnamese. Pharmacogenomics, 22(1), 1–12. https://doi.org/10.2217/pgs-2019-0146

13. Nguyen DV, Anderson J, Vidal C, Fulton R, Li J, Fernando SL. The utility of surrogate markers in predicting HLA alleles associated with adverse drug reactions in Vietnamese. Asian Pac J Allergy Immunol. 2019 Aug 18;. doi: 10.12932/AP-170219-0493. [Epub ahead of print] PubMed PMID: 31421661.

14. Nguyen AD, Luong CQ, Chu HC, Nguyen VKD, Nguyen CV, Nguyen TA, Nguyen QH, Mai TD, Nguyen DV, Nguyen BQ, Tran TH, Dao PV, Nguyen DT, Nguyen NN, Do SN. Successful management of severe diabetic ketoacidosis in a patient with type 2 diabetes with insulin allergy: a case report. BMC Endocr Disord. 2019 Nov 11;19(1):121. doi: 10.1186/s12902-019-0451-7. PubMed PMID: 31711488; PubMed Central PMCID: PMC6849168.

15. Zhang C, Van DN, Hieu C, Craig T. Drug-induced severe cutaneous adverse reactions: Determine the cause and prevention. Ann Allergy Asthma Immunol. 2019 Nov;123(5):483-487. doi: 10.1016/j.anai.2019.08.004. Epub 2019 Aug 7. PubMed PMID: 31400461.

16. Nguyen DV, Vidal C, Chu HC, van Nunen S. Human leukocyte antigen-associated severe cutaneous adverse drug reactions: from bedside to bench and beyond. Asia Pac Allergy. 2019 Jul;9(3):e20. doi: 10.5415/apallergy.2019.9.e20. eCollection 2019 Jul. Review. PubMed PMID: 31384575; PubMed Central PMCID: PMC6676067.

17. Nguyen DV, Vidal C, Chu HC, van Nunen S. Developing pharmacogenetic screening methods for an emergent country: Vietnam. World Allergy Organ J. 2019;12(5):100037. doi: 10.1016/j.waojou.2019.100037. eCollection 2019. Review. PubMed PMID: 31198488; PubMed Central PMCID: PMC6558218.

18. Nguyen DV, Vidal C, Chi HC, Do NTQ, Fulton R, Li J, Fernando SL. A novel multiplex polymerase chain reaction assay for detection of both HLA-A*31:01/HLA-B*15:02 alleles, which confer susceptibility to carbamazepine-induced severe cutaneous adverse reactions. HLA. 2017 Dec;90(6):335-342. doi: 10.1111/tan.13143. Epub 2017 Oct 2. PubMed PMID: 28884973.

19. Nguyen DV, Vida C, Chu HC, Fulton R, Li J, Fernando SL. Validation of a Rapid, Robust, Inexpensive Screening Method for Detecting the HLA-B*58:01 Allele in the Prevention of Allopurinol-Induced Severe Cutaneous Adverse Reactions. Allergy Asthma Immunol Res. 2017 Jan;9(1):79-84. doi: 10.4168/aair.2017.9.1.79. PubMed PMID: 27826965; PubMed Central PMCID: PMC5102839.

20. Nguyen DV, Vidal C, Chu HC, Do NT, Tran TT, Le HT, Fulton RB, Li J, Fernando SL. Validation of a novel real-time PCR assay for detection of HLA-B*15:02 allele for prevention of carbamazepine - Induced Stevens-Johnson syndrome/Toxic Epidermal Necrolysis in individuals of Asian ancestry. Hum Immunol. 2016 Dec;77(12):1140-1146. doi: 10.1016/j.humimm.2016.08.010. Epub 2016 Aug 17. PubMed PMID: 27544047.

21. Nguyen DV, Vidal C, Li J, Fulton RB, Fernando SL. Validation of a rapid test for HLA-B*58:01/57:01 allele screening to detect individuals at risk for drug-induced hypersensitivity. Pharmacogenomics. 2016 Apr;17(5):473-80. doi: 10.2217/pgs.15.185. Epub 2016 Mar 30. PubMed PMID: 27027663.

22. Nguyen DV, Chu HC, Nguyen DV, Phan MH, Craig T, Baumgart K, van Nunen S. HLA-B*1502 and carbamazepine-induced severe cutaneous adverse drug reactions in Vietnamese. Asia Pac Allergy. 2015 Apr;5(2):68-77. doi: 10.5415/apallergy.2015.5.2.68. Epub 2015 Apr 29. PubMed PMID: 25938071; PubMed Central PMCID: PMC4415182.

23. Van Nguyen D, Chu Chi H, Van Nguyen D, Craig TJ, van Nunen S. Description of 3 cases in Vietnam of aspirin desensitization in patients with coronary artery disease and coexisting aspirin hypersensitivity. World Allergy Organ J. 2012 Nov;5(11):170-3. doi: 10.1097/WOX.0b013e3182718327. PubMed PMID: 23282385; PubMed Central PMCID: PMC3651182.