About

Nguyen Van Tinh, PhD has nearly 10 years of experience in the field of cell research, biological activity of proteins and peptides in cancer treatment applications, research on safety and applicability of materials biological. Dr. Tinh successfully defended his PhD in biomedical research at Pukyong University, South Korea in 2017. After that, he worked as Postdoc in the field of cell research, creating biomaterials, and in vitro and in vitro test application. Dr. Tinh worked at Vinmec in December 2017 with the job of extracting and researching stem cells, managing Lab at Vinmec High-Tech Center. Currently the leader of the Vinmec cord blood bank and the leader of the AABB (American Association of Blood Banks) standard project for Vinmec High-Tech Center. Currently, Dr. Tinh is actively involved in Vinmec Tissue Bank development projects.

Roles

Head of cord blood bank

Experience
  • 2008 - 2009: Staff of QC at Saigon Corporation V.E.T Ho Chi Minh City

  • 2009 - 2010: Research on Dengue Fever at Preventive Medicine Center of Ho Chi Minh City

  • 2017 - 2018: Staff at Vinmec Research Institute of Stem Cell and Gene Technology

  • 2019 - Present: Vinmec Tissue Bank, Hi-tech Center Vinmec HealthCare System.

 

RESEARCH INTEREST

  • Screening and isolation of bioactive materials from natural organism and ecosystem

  • Study of biochemical properties, molecular interaction and regulatory mechanism of exogenous biomolecules such as peptide and protein

  • Safety and bioavailability of bioactive materials and functional foods.

  • Application of natural biomolecules in nutraceutical, cosmetical, pharmaceutical, and medicinal products (in vitro and in vivo)

  • Development of marine-integrated cell & tissue regenerative biomedical substances

  • Umbilical cord blood bank, isolation stem cell.

Awards and recognition

Korean patent 10-2011-0092951 (Submitted; 2011.09.15) / 10-1322478 (Registered; 2013.10.21) Abalone intestine gastro-intestinal digests having effects of inhibiting MMP activity and a pharmaceutical composition containing the same as an active ingredient) MMP활성 억제 효과를 갖는 전복 내장 위장관 소화가수분해물 및 이를 유효성분으로 함유하는 약학 조성물) * IPET

Books, articles, and research

13. Nguyen, P. H., Nguyen, V. T., Chu, T. T., Truong, L. H., Do, T. T. H., Nguyen, T. D., ... & Nguyen, L. T. (2020). Factors Affecting Human Umbilical Cord Blood Quality Before Cryopreservation: The Importance of Birth Weight and Gestational Age. Biopreservation and Biobanking, 18(1), 18-24.

12. Nguyen, V. T., Ko, S. C., Oh, G. W., Heo, S. Y., & Jung, W. K. (2019). Effects of Psidium guajava Leaf Extract on Apoptosis Induction Through Mitochondrial Dysfunction in HepG2 Cells. 한국미생물· 생명공학회지, 47(1), 43-53.

11. Chu Thị Thảo, Thân Thị Trang Uyên, Nguyễn Đắc Tú, Nguyễn Hoàng Phương, Bùi Việt Anh, Nguyễn Văn Tình*, Phân tích các yếu tố liên quan đến chất lượng đơn vị tế bào gốc máu cuống rốn thu thập và xử lý tại bệnh viện đkqt vinmec năm 2017. Tạp chí y học Việt Nam tập 467 tháng 5-số đặc biệt 2018

10. Nguyen, V.T., Ko, S.C., Heo, S.J., Kang, D.H., Oh, C., Kim, K.N., Jeon, Y.J., Kim, Y.M., Park, W.S., Choi, I.W. and Park, N.G., 2018. Ciona intestinalis calcitonin-like peptide promotes osteoblast differentiation and mineralization through MAPK pathway in MC3T3-E1 cells. Process Biochemistry, 67, pp.127-138. 2018

9. Nguyen V.T., Ko S.C., Oh G.W., Heo S.Y., Jeon Y.J., Park W.S., Choi I.W., Choi S.W., Jung W.K., Anti-inflammatory effects of sodium alginate/gelatine porous scaffolds merged with fucoidan in murine microglial BV2 cells. International Journal of Biological Macromolecules (Dec., 2016)

8. Chandika P., Ko S.C., Oh G.W., Heo S.Y., Nguyen V.T., Jeon Y.J., Lee B., Jang C.H., Kim G.H., Park W.S., Chang W.S., Choi I.W., Jung W.K., Fish collagen/ alginate/ chitooligosaccharides integrated scaffold for skin tissue regeneration application. International Journal of Biological Macromolecules. 81 504-513 (Nov., 2015).

7. Oh G.W., Ko S.C., Heo S.Y., Nguyen V.T., Kim G.H., Jang C.H., Park W.S., Choi I.W., Qian Z.J., Jung W.K., A novel peptide purified from the fermented microalga Pavlova lutheri attenuates oxidative stress and melanogenesis in B16F10 melanoma cells. Process Biochemistry 50(8) 1318-1326 (Aug., 2015)

6. Nguyen V.T., Qian Z.J., Lee B., Heo S.J., Kim K.N., Jeon Y.J., Park W.S., Choi I.W., Jang C.H., Ko S.C., Park S.J., Kim Y.T., Kim G.H., Lee D.S., Yim M.J., Je J.Y., Jung W.K., Fucoxanthin derivatives from Sargassum siliquastrum inhibit matrix metalloproteinases by suppressing NF-kB and MAPKs in human fibrosarcoma cells. Algae 29(4) 355-366 (Dec., 2014)

5. Nguyen V.T., Lee J.S., Qian Z.J., Li Y.X., Kim K.N., Heo S.J., Jeon Y.J., Park W.S., Choi I.W., Je J.Y., Jung W.K., Gliotoxin isolated from marine fungus Aspergillus sp. Induced apoptosis of human cervical cancer cell and human chondrosarcoma cell. Marine Drugs 12(1) 69-87 (Jan., 2014)

4. Nguyen T.H.M, Qian Z.J., Nguyen V.T., Choi I.W., Heo S.J., Oh C.H., Kang D.H., Kim, G.H., and Jung W.K., Tetrameric peptide purified from biodiesel by-products of Nannochloropsis oculata induces osteoblastic differentiation through MAPK and Smad pathway on MG-63 and D1 cells. Process Biochemistry 48 1387-1394 (Sep., 2013)

3. Nguyen V.T., Qian Z.J., Ryu B.M., Kim K.N., Kim D.K., Kim Y.M., Jeon Y.J., Park W.S., Choi I.W. Je J.Y., Jung W.K., Matrix metalloproteinases (MMPs) inhibitory effects of an octameric oligopeptide isolated from abalone Haliotis discus hannai. Food Chemistry 141 (1) 503-509 (Nov., 2013)

2. Nguyen V.T., Qian Z.J., Jung, W.K., Abalone (Haliotis discus hannai) intestine digests with different molecule weights inhibit MMP-2 and MMP-9 expression in human fibrosarcoma cells. Fisheries & Aquatic Sciences 15(2) 137-143 (Jun., 2012)

1. Nguyen V.T., Qian Z.J., Jung, W.K., Matrix Metalloproteinase: Inhibitory Effect of Marine Substances on MMP-2 and MMP-9. J. Chosun Natural Science 4 255-264 (Dec., 2011)

Oral presentation

1. Van-Tinh Nguyen, Zhong Ji Qian, Won Kyo Jung. A novel angiotensin I-converting enzyme (ACE) inhibitory peptide from biodiesel byproducts of marine algae nannochloropsisoculata. ISGMA 2012 international symposium on green manufacturing and applications. Aug 08-27, 2012, Jeju Island, Korea.

2. Van-Tinh Nguyen and Won-Kyo Jung. Effects of gliotoxin isolated from marine fungus Aspergillus sp. on apoptosis in human cervical cancer cell and human chondrosarcoma cell. KSABC 2012 The Korean Society for Applied Biological Chemistry. November 8-10, 2012. Kimdaejung Convention Center, Gwangju, Korea.

3. Van-Tinh Nguyen Zhong Ji Qian and Won-Kyo Jung. Apoptosis induction of gliotoxin isolated from marine fungus Aspergillus sp. in human cervical cancer cell and human chondrosarcoma cell in vitro. 1st Symposium on Marine Enzymes and Polysaccharides. Nha Trang, Vietnam 10-17, December 2012: Nha Trang, VAST, 2012. – 87c. Conference hall, NHA NGHI T78 (44, TRAN PHU)

4. Van-Tinh Nguyen, Nam Gyu Park and Won-Kyo Jung. Ciona intestinalis calcitonin enhances differentiation and mineralization of osteoblastic MC3T3-E1 cells through MAPK pathway. WAS2015 (Would Aquaculture Society). Jeju, Korea 2015.05.26.-30

5. Van-Tinh Nguyen and Won-Kyo Jung. Anti-inflammatory effects of fucoidan added with Sodium alginate/gelatine 3D scaffolds in BV2 microglial cells. ICCFB2015 (The international conference on chemical engineering, food and biotechnology). 2015.10.30.-10.31. Ho chi minh city, Vietnam

Services

Collecting, processing, and storgare cord blood. Research and culture stem cells.

Education
  • 09/2004 - 09/2008: B.Sc. Biology Science, Ho Chi Minh City University of Natural Sciences/Vietnam

  • 09/2010 - 09/2012: M.Sc. Marine Life Science, Chosun University/Korea

  • 09/2013 - 02/2017: Ph.D. Biomedical Engineering, Pukyong National University/Korea

  • 03/2017 - 10/2017: Postdoctoral Researcher Biomedical Engineering, Pukyong National University/Korea.

Languages spoken
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