Treatment of Non-Hodgkin's Malignant Lymphoma

Non-Hodgkin's lymphoma is a cancer that originates from the lymphatic system, which is one of the cancers that has been on the rise in recent years. The early detection of the first signs of the disease will help increase the effectiveness of treatment and prolong the patient's life.

According to statistics, each year Vietnam has more than 2000 cases of being diagnosed with non-Hodgkin's lymphoma, this disease can happen to anyone, regardless of age or sex.
Non-Hodgkin's lymphoma is a lymphocytic leukemia disease, at first onset, the disease usually manifests in the lymph nodes (about 60%) or extranodal tumors and any organs and locations in the body. patient. Histopathologically, non-Hodgkin's lymphoma is mainly found in B-lymphocytes, the rest are T-lymphocytes and NK cells.

Until now, researchers have not found the main cause of Non-Hodgkin Lymphoma, however, in some cases, the factors that increase the risk of the disease may be systemic. A weakened immune system causes the body to produce too many abnormal lymphocytes.
Normally, when old lymphocytes die, the body will make new cells to replace them, however, in patients with non-Hodgkin lymphoma, the lymphocytes do not die, they continue to grow. grow and divide and lead to an oversupply of lymphocytes that crowd the lymph nodes causing them to swell and cause disease.

Some typical symptoms in people with non-Hodgkin lymphoma include:
Persistent fatigue Fever Night sweats Swelling in the neck, armpits or groin, painless lymph nodes Abdominal pain or swelling Chest pain, cough, shortness of breath Unexplained weight loss

Currently, non-Hodgkin lymphoma is treated with 4 main methods including: radiation therapy, chemotherapy, immunotherapy and targeted therapy. During the conventional treatment of non-Hodgkin lymphoma, doctors may apply a combination of treatments or prescribe surgical removal of the tumor or stem cell transplant in cases of need.
However, in order to be able to come up with a treatment regimen for non-Hodgkin's lymphoma that is suitable for the patient's health situation, the doctor will need to rely on a number of factors such as: Stage of the disease, type of lymphoma Non-Hodgkin's lymphoma, possible side effects, patient's health...
Treatment of non-Hodgkin lymphoma with chemotherapy Chemotherapy for non-Hodgkin's lymphoma is considered the main method In the course of chemotherapy, the patient may be prescribed a number of drugs, depending on the stage of the disease, different chemotherapy regimens will be used.

Treatment of non-Hodgkin lymphoma with radiation Radiation therapy for non-Hodgkin lymphoma will be applied after or in addition to chemotherapy.
Treatment of non-Hodgkin lymphoma with immunotherapy Immunotherapy can help strengthen the body's defenses against tumors in patients with non-Hodgkin lymphoma. For this method, doctors will use monoclonal antibodies, or drugs capable of inhibiting CAR-T cells and immune checkpoints in the patient's body. Immunotherapy can improve or help restore the body's immune system function.
Treatment of non-Hodgkin lymphoma with targeted therapy Targeting is a treatment for malignant non-Hodgkin lymphoma that can help stop the growth and spread of cancer cells and help limit damage to healthy cells in the patient's body.
In addition to the 4 methods of treating non-Hodgkin's lymphoma, the doctor can, depending on the situation, only treat the patient with a marrow transplant or a stem cell transplant.
In the treatment of malignant non-Hodgkin lymphoma, disease control plays a very important role. Patients need to absolutely adhere to the treatment regimen as well as the care given by the doctor.
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