Medicine for leg cramps

Research from scientists has shown that quinine used to treat cramps can cause serious side effects when taken in excess, especially an increased risk of death.

Quinine is approved by the US Food and Drug Administration (FDA) for the treatment of malaria. However, this drug is also used arbitrarily by many patients in the treatment of cramps, despite warnings about dangerous side effects to health. Accordingly, quinine can cause side effects including purpura, thrombocytopenia, thrombosis, potentially life-threatening hemolytic-uremic syndrome, and kidney damage.
Scientists at the University of Paris - Est Creteil France also proved that some drinks such as tonic water, energy drinks... contain quinine, which increases the risk of exposure to this compound every day, from That increases the chance of quinine side effects.

Research from scientists at the University of Paris - Est Creteil France used data from the Health Improvement Network (THIN) to conduct the study. Accordingly, the study was conducted on 175,195 adults, of whom 44,669 were prescribed at least 100 milligrams of quinine per day to treat muscle cramps or restless legs syndrome. A dose of 100 milligrams of quinine is equivalent to consuming at least about 1 liter of tonic water, energy drinks, etc. The mean time of follow-up and study was 5.7 years. The results showed that there were 11,598 deaths (equivalent to an incidence of 4.2 per 100 persons per year) among those exposed to quinine and 26,753 deaths (equivalent to a rate of 3.2 per 100 persons per year). per year) of 130,496 who were not exposed to quinine.
Adults taking daily doses of quinine between 300 and 399 milligrams had an 83% increased risk of death compared with a 100-milligram dose and a 25% higher risk of death for those exposed to a 200-299-milligram dose. quinine. Research has also shown a link between long-term quinine exposure and an increased risk of death in people under the age of 50.
Thus in addition to the effects of quinine in the treatment of calf cramps in the legs. This drug also causes dangerous side effects, so it should be noted and cautious when using quinine in treatment.
It's best before using any medicine you should consult with doctors, experts to have appropriate indications for your current health condition.