HPV virus in some oral diseases

Human papillomavirus (HPV). There are more than 100 types of HPV virus, of which about 80 types cause skin disease and 40 types cause mucosal disease. Oral HPV infection is the cause of a number of dangerous diseases such as oropharyngeal cancer.
The way of transmission of HPV virus is direct contact through the skin and mucous membranes when the lesions are infected with HPV. HPV is also primarily sexually transmitted. In addition, other less common transmission routes are: kissing, mother-to-child transmission at birth, self-infection, use of tools infected with HPV... Here are some oral diseases caused by HPV.
Warts This type of oral cavity disease is uncommon and is mainly caused by HPV types 2, 4. Warts are manifested as papillae lesions, white in color due to thickening of the horns.
Genital warts Clinically, warts are common diseases caused by HPV types 6, 11, 16, 18. Adolescents and young people are susceptible. The route of transmission of the disease is through oral sex.
The disease manifests as papillary lesions, rough surface, peduncle or sessile. The disease can cause dysplasia, which can more seriously lead to cancer when infected with high-risk types of HPV.

Multifocal epidermal hyperplasia This oral disease, also known as Heck, is caused by HPV types 13 and 32. The risk factor for the disease is poor hygiene or HLA-DR4 gene...
The disease has many small papules, slightly rough surface, little thickening, usually on lips, tongue, cheek mucosa, and rarely malignancy risk.
Oral Leukoplakia The HPV virus also causes lesions in the oral mucosa. With oral leukoplakia, the lesions within leukoplakia are red or white, flat, smooth, firm-surfaced macules that often appear on the floor of the mouth. Mixed macules of both red and white have a higher risk of cancer.
The rate of disease progressing to squamous cell carcinoma is 4%. Studies show that the viral load in this type of lesion is usually low, rarely the HPV virus integrates into the genome, so the lesion is less likely to turn into a malignancy.

Oral cancer Oral cancer caused by the HPV virus is a completely different form of cancer that originates deep inside the tonsils. The way the HPV virus causes oral cancer is similar to the way this virus causes cervical cancer. That is, the viral DNA integrates with the patient's DNA in the nucleus of healthy cells, then produces two harmful proteins, E6 and E7. They bind to and disable two important anti-cancer proteins, p53 and pRb.
However, HPV positive and negative oral cancer patients are completely different. HPV-positive patients typically have multiple sex partners, have oral sex, and are less likely to smoke or drink alcohol. Meanwhile, HPV-negative patients are often heavy drinkers and smokers.
Oral HPV infection can cause serious damage and disease. To limit the spread of infection and avoid the risk of developing malignancies, it is recommended to use safety measures when having sex, especially to avoid oral sex, and to limit the use of tobacco. drink alcohol, ...
Vinmec International Health System is a reputable and reliable place for cervical cancer vaccination. Currently, there are 2 vaccines that are widely used in the world and are licensed for circulation in Vietnam as well as in Vinmec: Gardasil (prevents 4 strains of HPV: 16,18,6,11 manufactured by the US). Indicated for use in women 9 - 26 years old and Cervarix (prevents 2 strains of HPV: 16,18 manufactured by Belgium) is indicated for women 10 - 25 years old.
These two vaccines have some basic differences in terms of the number of preventable HPV strains, the target population, the vaccination schedule, and the preventive effect.
When suspected of being infected with HPV, you can go to Vinmec International General Hospital for examination and treatment. There is a team of doctors specializing in Infectious Diseases with rich expertise and experience; modern medical equipment, up to international standards; professional service quality, helping to improve the effectiveness of HPV diagnosis and treatment.