ERA test determines the implantation window of the embryo

The article is professionally consulted by Master, Doctor Nguyen Ngoc Chien - Clinician - Reproductive Support Center - Vinmec Times City International Hospital.

ERA stands for Endometrial receptivity analysis, a modern test method used in in vitro fertilization in developed countries around the world. The ERA test helps assess a woman's ability to accept embryos in the lining of the uterus.
ERA test is a modern test method, applying the latest technology today. The test will analyze the expression levels of hundreds of genes in the lining of the uterus. From there, consider the most optimal time to proceed to place the embryo in the uterus to promote implantation and pregnancy.
To perform this test the endometrium is collected for analysis. The results of the analysis will show whether it is necessary to change the time of embryo transfer.

Normally during natural fertilization, embryos are formed at the end of the fallopian tubes and move into the uterus, implant and develop. However, with in vitro fertilization, embryos are formed outside the body and placed in the uterus on a certain day of the menstrual cycle. During each cycle, the lining of the uterus will have a short period of time to be able to receive the implanted embryo (implantation window). The ERA test was conceived to help doctors determine the implantation window of the uterine lining and assess the embryo's ability to accept embryos, thereby improving the chances of IVF success.

The ERA test is a method of assessing the embryo's ability to accept embryos of the mucosa commonly used in the process of in vitro fertilization. Previously, the patient needed to prepare the mucosa to be able to transfer the stored embryos on a fixed day according to the protocol. With ERA testing, the patient can determine the implantation window of the uterine lining, and determine the most suitable time for embryo transfer to the patient.
In addition, the embryo only attaches and develops in the uterine cavity when the embryo moves into the uterus at the right stage when the lining can receive the embryo. However, this intake time will be different in different patients. Therefore, doctors must rely on the results of the ERA test to determine the best time for the lining of the uterus to be able to receive embryos.

The ERA test is commonly used in the form of in vitro fertilization. However, not all patients need this test. The ERA test is indicated only in the following cases:
The patient has had multiple failed embryo transfers (≥ 2 times). The patient had good embryo quality and good mucosa but failed embryo transfer for unknown reasons. There have been 1 or more failed attempts to use the recipient's eggs. Although embryo quality is good, uterine lining is good, but embryo transfer failure of unknown cause. Although ERA testing is recommended for cases of repeated IVF failures, unexplained failures or repeated miscarriages,... However, as noted, the ERA test is Modern analytical methods make many cases of in vitro fertilization successful for the first time. Therefore, if there are conditions and needs, the patient can completely request an ERA test to increase the success rate of the in vitro fertilization process.

According to statistics, up to 35% of women have different nesting windows than others. Therefore, the process of embryo implantation in the form of artificial insemination is hindered and faced with many difficulties. This is the leading cause of in vitro fertilization failure when the embryo is standard and the uterus is completely normal.

When the ERA test was used to determine the "implantation window", doctors accurately assessed the endometrial's ability to accept embryos and increased the success rate for IVF. 25% more testing.
The ERA test is the recommended method for IVF cases because the results of this method improve the success rate for this process. If you want IVF to be successful the first time or have failed IVF many times, it is advisable to use the ERA test before embryo implantation. This test requires qualified doctors and modern equipment to perform. Therefore, you should choose reputable medical facilities to perform.
Vinmec IVF Reproductive Center is the address of infertility - infertility treatment chosen by many couples. So far, the Center has performed fertility support for over 1000 infertile couples with a success rate of 45%-50%. This rate is equivalent to developed countries such as the UK, USA, Australia,... Vinmec IVF Center is also the first place in Vietnam to conduct ERA test to improve the success rate in IVF. , especially with difficult cases.
The medical team at IVF Vinmec are all leading experts in the field of obstetrics and gynecology in the country and internationally, trained at leading centers around the world such as in the US, Singapore, Japan, Australia and the US. Famous fertility centers in the world. Vinmec Fertility Center can perform most of the advanced assisted reproductive techniques in the world such as: classical IVF, ICSI (intracytoplasmic sperm injection), embryo freezing, culture - embryo transfer, support embryo rupture, reduce multiple pregnancies...help realize the dream of parenthood of hundreds of families across Vietnam.
If you need to perform ERA test or IVF at Vinmec, please book an appointment directly at the website or contact the hotline for service.