Uses of Irinotecan Liposome (Onivyde)

The drug Irinotecan Liposome is effective in the treatment of pancreatic carcinoma with metastasis. This is a prescription drug, so make sure you consult your doctor before using it.

Irinotecan Liposome drug also known as Onivyde drug. The drug works by blocking the action of an enzyme in the cell called topoisomerase I.
Irinotecan Liposome drug inhibits the enzyme topoisomerase by blocking the action of an enzyme in cells called topoisomerase, which is necessary for the normal growth of cells. cell proliferation and tumor growth. Cells need this enzyme to keep their DNA in the proper shape when they are dividing. Blocking this enzyme leads to a breakdown of DNA that causes cancer cells to die.

Irinotecan Liposome is given intravenously (IV, directly into a vein). Dosage depends on the individual's weight. Before treatment with Irinotecan Liposome, people with cancer will be treated with corticosteroids, antiemetics and antidiarrheals. Irinotecan Liposome is not used alone, but in combination with other chemotherapy drugs.

Blood levels of Irinotecan Liposome may be affected by certain foods and medications. Therefore, they should be avoided for 1 to 2 weeks before treatment.
Foods and drugs that can cause interactions with Irinotecan Liposome drugs: Grapefruit, grapefruit juice, Carbamazepine, Ketoconazole, Rifampicin, Phenytoin, Phenobarbital. You need to inform your treating doctor about all medications and supplements you are taking to minimize possible adverse interactions with your health.

Below are some unwanted effects of Irinotecan Liposome:
Diarrhea: Diarrhea is a common undesirable effect when using Irinotecan Liposome. In some cases, diarrhea can lead to severe dehydration. Therefore, you need to inform the treating doctor to have a method to control this condition. Runny nose, profuse salivation, watery eyes, sweating, and cramps that may accompany diarrhea occur during the first day of Irinotecan Liposome use. Low white blood cell count (leukopenia or neutropenia): You should notify your healthcare provider immediately if a fever above 38°C is accompanied by a sore throat or cold, difficulty breathing, cough, burning when urinating. Decreased appetite: Cancer treatment can affect your appetite. Some ways to increase appetite include: splitting meals into 5 to 6 meals a day, taking nutritional supplements, avoiding any foods that you find smelly or tasteless. delicious, use spices to enhance the taste. Mouth ulcers or mucositis: Some cancer treatments can cause sores or sores in your mouth or throat. Typical signs of mouth ulcers include your mouth, tongue, inside of your cheeks, and throat becoming white, sore, or sore. Practicing regular oral care can help prevent or control mouth sores. If mouth sores become painful, your doctor may prescribe pain relievers. Other less common side effects:
Allergic reactions: In some cases, you may have an allergic reaction to this medicine. Signs of an allergic reaction include shortness of breath or difficulty breathing, chest pain, swelling of the face, eyelids or lips, rash, flushing, itching, or a drop in blood pressure. If you notice any changes in sensation during the infusion, notify your healthcare provider right away. Lung changes: Irinotecan Liposome drug may be the cause of interstitial lung disease. This disease can leave scarring and hardening of lung tissue. If you notice a feeling of shortness of breath or worsening, coughing, wheezing or shortness of breath, you should contact your treating physician as soon as possible.

Exposure of the fetus to Irinotecan Liposome can cause birth defects, so you should not become pregnant or father a child while using this medicine. You should use effective birth control during treatment and for at least 1 month for women and 4 months for men after treatment with Irinotecan Liposome. Lactation: You should not breast-feed while using Irinotecan Liposome and for 1 month after the last dose of treatment. Irinotecan Liposome is a prescription drug, so make sure you consult your doctor before using it. Hopefully, the article has provided you with useful information about the uses, doses and precautions when using Irinotecan Liposome.