Codeine-Butalbital-ASA-Caff: Uses, indications and precautions when using

Tension headaches are a very common problem in modern society. The treatment of headaches is increasingly demanding in terms of effectiveness and convenience in use, notably Codeine-Butalbital-ASA-Caff. So what does Codeine-Butalbital-ASA-Caff do?

Codeine-Butalbital-ASA-Caff is a combination medication indicated for the treatment of tension-type headaches. The ingredients in the drug include:
Codeine: an opioid pain reliever that relieves pain by acting on the pain control center of the brain; Aspirin: belongs to the group of anti-inflammatory, analgesic; Caffeine : enhances the effect of aspirin; Butalbital: sedation, anxiety relief, drowsiness and relaxation.

Read the instructions for use carefully before starting to use Codeine-Butalbital-ASA-Caff. Accordingly, this drug is absorbed orally, used every 4 hours for headache or as directed by the doctor. Do not take more than 6 pills per day and only the smallest effective dose should be used. When using, the patient needs to drink with plenty of water unless otherwise directed by the doctor.
Do not lie down for at least 10 minutes after taking Codeine-Butalbital-ASA-Caff to limit the side effects of nausea. Patients with nausea can take the drug with food.
The dose of Codeine-Butalbital-ASA-Caff depends on the severity of the headache, age and drug tolerance of each person. Codeine-Butalbital-ASA-Caff is most effective when a patient has just had the first signs of a headache. If your headache symptoms get worse, the medication may not work as well.
Users do not arbitrarily increase the dose or use Codeine-Butalbital-ASA-Caff more times or longer than indicated. At the same time, when it is necessary to stop the drug, the patient must follow the instructions of the doctor exactly. Abrupt discontinuation of the drug can cause withdrawal symptoms, especially in patients taking the drug for a long time or in high doses. To prevent this, the doctor may instruct the patient to reduce the dose slowly.
Recognize signs of withdrawal syndrome such as restlessness, psychotic mood changes (such as anxiety, trouble sleeping, suicidal thoughts), watery eyes, runny nose, nausea, loose stools, sweating odor, muscle pain, or behavior changes.
Some subjects when using Codeine-Butalbital-ASA-Caff drugs can cause addiction. This risk is increased if the patient has a history of stimulant use disorders (such as drug and alcohol abuse or addiction).

Possible side effects when taking Codeine-Butalbital-ASA-Caff include:
Nausea, vomiting; Stomach upset, flatulence; Trembling limbs; Constipation ; Dry mouth ; Dizziness, dizziness; Drowsiness or trouble sleeping. Some other serious side effects of Codeine-Butalbital-ASA-Caff require immediate medical help, including:
Having episodes of sleep apnea; Mental and mood changes; fast or irregular heartbeat; Increased thirst or frequent urination; Hearing changes; easy bruising or bleeding; Signs of infection (fever, persistent sore throat...) Ợ sour, uncomfortable swallowing; Dark urine, yellow eyes, jaundice; Signs of kidney problems; Signs of adrenal insufficiency such as loss of appetite, unusual tiredness, weight loss; Faint; Convulsions; Black stools, stomach pain, severe abdominal pain, vomit that looks like coffee grounds; Stupid speech, weakness on one side of the body. Codeine component in the drug Codeine-Butalbital-ASA-Caff, when entering the body, it will be converted into a strong opioid (morphine). As a result, in some people, the process is faster and more intense than usual, leading to an increased risk of serious side effects. Patients should call the medical facility immediately when any of the following signs: slow breathing, shallow breathing, drowsiness, coma, confusion.

Before using Codeine-Butalbital-ASA-Caff, the patient should inform the doctor about the following history:
Allergy to aspirin, caffeine, codeine, butalbital or other barbiturates (such as phenobarbital), drugs other nonsteroidal anti-inflammatory drugs, other opioids (such as morphine) or xanthine derivatives (such as theophylline); Any other allergic disease; Asthma (including history of shortness of breath with runny or stuffy nose after taking aspirin or other NSAIDs) Brain disease (eg, seizures, head injury, tumor, increased intracranial pressure) Shortness of breath (such as chronic obstructive pulmonary disease, sleep apnea); Bleeding or coagulopathy; Disorders of certain enzymes; Pancreatitis; Cardiovascular disease (such as irregular heartbeat, recent angina) Certain enzyme deficiencies such as pyruvate kinase or G6PD deficiency); Gout; Liver disease, kidney disease; Heartburn; Nasal polyps; Certain diseases of the spine; Gallbladder disease; Personal/family history of substance use disorder; Mental illness or mood disorder; Adrenal gland disease (such as Addison's disease); Difficulty urinating due to an enlarged prostate or narrowing of the urethra; Hypothyroidism; Recent abdominal or intestinal surgery Obesity. Codeine-Butalbital-ASA-Caff can cause stomach bleeding as a side effect. Daily alcohol use and smoking, especially when used in combination with Codeine-Butalbital-ASA-Caff increase the risk of stomach bleeding. Therefore, limit alcohol use and stop smoking.
Codeine-Butalbital-ASA-Caff contains aspirin. Children and adolescents under 18 years of age should not take aspirin if they are having chickenpox, flu, or after receiving a live virus vaccine without consulting a doctor to avoid Reye's syndrome.
Some children are more sensitive to codeine side effects such as drowsiness, confusion or slow breathing, shallow breathing, wheezing.
Older adults tend to be more sensitive to Codeine-Butalbital-ASA-Caff side effects such as confusion, dizziness, drowsiness, slow/shallow breathing, bleeding/stomach ulcers.
Before using Codeine-Butalbital-ASA-Caff, women of childbearing age should talk to their doctor about the risks and benefits. Notify if you are pregnant or planning to become pregnant as Codeine-Butalbital-ASA-Caff is not recommended for use during pregnancy. The ingredients in the drug can be harmful to the fetus, affecting the process of normal labor and delivery.
Codeine-Butalbital-ASA-Caff can pass into breast milk and affect a nursing infant. Therefore, breast-feeding while using this medicine is not recommended.

Some products that may interact with Codeine-Butalbital-ASA-Caff include:
Acetazolamide; Antacids; Anticholinergics (such as scopolamine); gout medicine (such as probenecid, sulfinpyrazone); Certain antibiotics such as penicillin, sulfamethoxazole; Darunavir; Dichlorphenamide; Drugs that are metabolized by the liver and affect their elimination, such as cimetidine, disulfiram, valproic acid; Lithium; MAO inhibitors (isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine); 6-mercaptopurine; Methotrexate; Methoxyflurane; Mifepristone; Naltrexone; some pain relievers (such as pentazocine, nalbuphine, morphine); Sodium oxybate. Codeine-Butalbital-ASA-Caff may increase the risk of bleeding when used concurrently with other drugs that also have the potential to cause bleeding such as clopidogrel antiplatelet agents, anticoagulants: dabigatran, enoxaparin, warfarin .
Codeine-Butalbital-ASA-Caff may increase the rate at which certain other drugs are eliminated from the body and affect how they work, such as corticosteroids, estrogens, felodipine, quinidine, beta-blockers (metoprolol), theophylline, doxycycline.
Check the ingredients in your medications (such as antihistamines, cough and cold medicines, or other headache medicines) as they may contain aspirin, caffeine, or ingredients that cause drowsiness. Also, check your current prescriptions because many medications with analgesic and antipyretic ingredients (NSAIDs such as ibuprofen, naproxen, aspirin, ketorolac) can increase the risk of side effects if taken with them. Codeine-Butalbital-ASA-Caff.
Some other drugs can affect the elimination of Codeine-Butalbital-ASA-Caff such as azole antifungals (such as ketoconazole), bupropion, fluoxetine, macrolide antibiotics (such as erythromycin), HIV drugs. (such as ritonavir), paroxetine, rifamycins, certain anticonvulsants (such as carbamazepine, phenytoin).
Codeine-Butalbital-ASA-Caff may decrease the effectiveness of hormonal contraceptives such as the pill, patch, or IUD, leading to an unwanted pregnancy. Talk to your doctor or pharmacist about using other reliable methods of birth control while using this medicine.

Reference source: webmd.com