Doripenem: Uses, indications and cautions when using

Doripenem is a beta-lactam antibiotic, belonging to the carbapenem group that has the ability to destroy Pseudomonas aeruginosa. The product is branded as Doribax and is distributed as a clear, colorless, clear 250 mg vial for intravenous solution.

Doripenem is used to treat a variety of bacterial infections, including Pseudomonas aeruginosa. This medicine, called a carbapenem-type antibiotic, works by stopping the growth of bacteria.

Doripenem is given by injection into a vein, usually every 8 hours or as directed by your doctor. The transmission rate should be slower than 1 hour. Dosage and length of treatment are based on each person's condition and response to treatment.
If you are self-administering Doripenem at home, you should get all instructions on preparation and administration steps from your healthcare professional. Before use, visually inspect the product for particles or discoloration. If so, do not use liquid. You should also learn more about how to safely store and dispose of medical supplies.
To get the best effect, you need to use Doripenem antibiotic at evenly spaced times. Taking this medicine at the same time each day will help you remember better and avoid missing doses. Continue taking the full dose of Doripenem until the end of the prescribed period of treatment, even if symptoms have resolved after a few days. Early discontinuation of the drug can create conditions for the bacteria to continue to grow, leading to a re-infection. Tell your doctor if your condition persists or gets worse.

Some possible side effects from taking Doripenem include:
Pain/redness/swelling at the injection site Nausea Headache Diarrhea If any of the above symptoms persist or get worse, tell doctor or pharmacist know immediately. It should be noted that when you were prescribed Doripenem, your doctor had judged that the benefits of treatment outweighed the risk of side effects. There are still many cases where this drug is safe to use without serious side effects.
Also, tell your doctor right away if you experience serious side effects, including: unusual tiredness and pale skin. Using this medicine for a long time or repeated often may lead to the development of oral thrush or a vaginal yeast infection. So contact your doctor if you notice:
White patches in the mouth Change in vaginal discharge Other new symptoms. Rarely, Doripenem can cause a very serious side effect of convulsions, requiring immediate medical help.
Another rare case of Doripenem causing severe diarrhea is caused by Clostridium difficile, a drug-resistant bacteria. This condition may occur within weeks to months of discontinuation of treatment. Note, do not use antidiarrheal drugs or opiates to avoid making the disease worse. Also, tell your doctor right away if you have any of the following symptoms:
Persistent diarrhea Abdominal pain Cramping Blood/mucus in the stool.

In fact, it is very unlikely that a serious allergic reaction to Doripenem will occur. However, see a doctor right away if you notice any of the following serious allergy symptoms:
Rash Itching/swelling (especially in the face/tongue/throat areas) Severe dizziness Shortness of breath. In addition, if the patient experiences other side effects not listed above, contact the doctor or pharmacist for assistance.

The following allergies should be told to your doctor or pharmacist before prescribing Doripenem:
Doripenem Carbapenems (eg, meropenem) Penicillin Cephalosporin Any other special allergic condition not listed. This product may contain inactive ingredients (in their inactive form), causing allergic reactions or other health problems. Drug users consult their pharmacist for more information.
Talk to your doctor or pharmacist about your medical history before taking medicine, especially of:
Kidney disease Epilepsy Stroke Doripenem can make live bacterial vaccines (such as vaccines) please typhoid ) does not work. So do not have any immunizations/vaccinations while using Doripenem unless directed to do so by your doctor.
Kidney function declines as you age, while Doripenem is filtered through the kidneys. Therefore, older adults may be at greater risk of side effects when using this medicine.
During pregnancy, the drug is only used when absolutely necessary and has been carefully weighed by the doctor about the risks and benefits compared to the benefits achieved. It is not known whether Doripenem passes into breast milk. Therefore, users should consult their doctor before breast-feeding.

Drug interactions can change the way Doripenem works or increase your risk of serious side effects. List all medications you are taking (including prescription/nonprescription and herbal medicines), then discuss them thoroughly with your doctor and pharmacist. Do not use, stop or change the dose without your doctor's approval. The product that may interact with this drug is valproic acid.

6.1. Overdose If you have overdosed, call a poison control center right away for instructions on what to do. Call 911 for severe symptoms such as fainting or difficulty breathing.
6.2. Skipping doses To get the most benefit from the medication, it is important that you receive each dose exactly on the schedule that your doctor recommends. If you have missed a dose, contact your doctor or pharmacist right away to set up a new dosing schedule. Do not arbitrarily double the dose to make up for the missed dose.
6.3. Storage Refer to the storage instructions on the product label or ask your pharmacist for details on storage. Keep Doripenem out of the reach of children.
Finally, patients being treated with Doripenem should have periodic medical tests (eg, complete blood count, kidney function tests) to monitor disease progression or check for other medical conditions. side effects. Consult a professional for more details.
Vinmec International General Hospital always receives and handles all health problems. Therefore, in the process of taking the drug, if there are any abnormalities, customers can contact the hospital to receive support from a specialist.

Reference source: webmd.com