Edarbychlor: Uses, indications and precautions when using

Edarbychlor is used to treat high blood pressure (hypertension). Controlling blood pressure in hypertensive patients helps prevent strokes, heart attacks, and kidney problems. However, not all patients with high blood pressure can use this drug.

Edarbyclor contains two main ingredients: azilsartan and chlorthalidone. Azilsartan works by dilating blood vessels so blood can flow more easily. It belongs to a class of drugs called angiotensin receptor blockers (ARBs). Chlorthalidone causes your body to excrete extra salt and water by making more urine. It is called a "water pill" or a diuretic.
Edarbyclor is indicated in the following cases:
High blood pressure Edarbyclor is contraindicated in the following cases:
Sympathectomy Type 2 diabetes Type 1 diabetes High cholesterol Gout Low blood magnesium levels High blood calcium Low blood sodium Low blood potassium Decreased kidney function Decreased urine production High blood uric acid level Pregnancy Stops urine production Low blood sodium Narrowing of the renal arteries Low blood pressure Decrease blood volume Kidney disease with the potential to decrease kidney function

Read the package insert from your doctor carefully before you start taking Edarbyclor and each time you get a refill. If you have any questions about how to use Edarbyclor, ask your doctor. Take Edarbyclor by mouth with or without food, as directed by your doctor, usually once daily. If you take Edarbyclor too close to bedtime, you may have to wake up to urinate in the middle of the night. Therefore, it is best to take this medicine at least 4 hours before bedtime. The dose of Edarbyclor is calculated based on your medical condition and response to treatment. Take Edarbyclor regularly to get the most benefit from it. To help you remember, take Edarbyclor at the same time each day. Keep taking Edarbyclor even if you feel well. Most people with high blood pressure do not feel sick. It may take several weeks before you get the full benefit of Edarbyclor. If you also take certain medications to lower cholesterol (such as cholestyramine, colestipol), take azilsartan/chlorthalidone at least 2 hours before or at least 4 hours after these medicines. Tell your doctor if your condition does not improve or if it worsens (your blood pressure readings remain high or increase) after treatment with Edarbyclor. Lifestyle changes that can help Edarbyclor work better include exercising, stopping smoking, and eating a low-cholesterol/low-fat diet. Tests including kidney function and blood levels of minerals such as potassium should be performed periodically to monitor your progress or check for Edarbyclor side effects. Check your blood pressure regularly while taking Edarbyclor. Learn how to self-monitor your blood pressure at home and share the results with your doctor.

While using Edarbyclor, you may feel dizzy or light-headed as your body has not yet adapted to the medicine. If one of these effects persists or gets worse, tell your doctor right away.
To reduce the risk of dizziness and lightheadedness when using Edarbyclor, get up slowly when getting up from a sitting or lying position.
Remember that your doctor has prescribed Edarbyclor because he or she has judged that the benefit to you outweighs the risk of side effects. Many people use Edarbyclor without any serious side effects.
Edarbychlor may cause excessive loss of body water (dehydration) and salt/minerals. Tell your doctor right away if you have any symptoms of dehydration or mineral loss, including: Extreme thirst, very dry mouth, muscle spasticity/weakness, fast/slow/irregular heartbeat , confusion.
Tell your doctor right away if you have any serious side effects of Edarbyclor, including: Fainting, severe fatigue, big toe/joint pain, symptoms of concentration high blood potassium (such as muscle weakness, slow/irregular heartbeat), signs of kidney problems (such as change in the amount of urine).
Get medical help right away if you have any very serious side effects of Edarbyclor, including: Reduced vision, eye pain.
A very serious allergic reaction to Edarbyclor is very rare. However, if you notice any symptoms of a serious allergic reaction to Edarbyclor, get medical help right away. These include: Rash, itching/swelling (especially of the face/tongue/throat), difficulty breathing, severe dizziness.
Below are Edarbyclor side effects by likelihood.
Common side effects of Edarbyclor include:
Low blood sodium Low blood potassium Low blood pressure Acid-base imbalance in the blood Diarrhea Uncommon side effects of Edarbyclor include:
Amount low blood magnesium Decreased kidney function High blood sugar Abnormal sexual function Postural hypotension Dizziness Low energy Decreased appetite Nausea Vomiting Diarrhoea Stomach cramps Rare side effect of Edarbyclor pills include:
Increased parathyroid gland activity Gout High blood calcium levels Hemolytic anemia Low blood count due to bone marrow failure Large purple or brown skin spots Thrombocytopenia Very low granulocyte count Low white blood cell count Low neutrophil level Myopia Allergic reaction causing vasculitis Vasculitis Interstitial pneumonia Hepatitis Bile duct obstruction Acute pancreatitis Interstitial nephritis Erythema multiforme Toxic epidermal necrolysis Syndrome Stevens-Johnson Skin rash with peeling Systemic lupus erythematosus Amount of uric acid in high blood pressure Anaphylaxis Secondary angle-closure glaucoma. Yellow eyes or skin Squamous cell cancer of the skin High levels of potassium in the blood Decreased kidney function Angioedema High cholesterol High levels of triglycerides in the blood Blurred vision Inflammation of the salivary glands Stomach or intestinal irritation Constipation Inability to erections Muscle spasms Feeling dizzy Fever Headache Anxiety Pinching sensation in the skin Body weakness Itching Low energy Skin rash Cough Nausea This is not a complete list of possible side effects occurrence of the drug Edarbychlor. If you notice other effects of Edarbyclor not listed above, contact your doctor.

Before taking Edarbyclor, tell your doctor if you are allergic to azilsartan or chlorthalidone and any other allergies, if any. Edarbyclor may contain inactive ingredients that can cause allergic reactions or other problems.
Before using Edarbyclor, tell your doctor or pharmacist your medical history, especially of: Kidney disease, liver disease, severe loss of body water and minerals (dehydration), mineral imbalance untreated substances (such as high/low potassium, low magnesium, high calcium, low sodium), gout, lupus.
Edarbyclor can make you dizzy and alcohol and marijuana can make you more dizzy. Do not drive, use machinery, or do anything that requires alertness while you are taking Edarbyclor, until you can do so safely. Limit alcoholic beverages and absolutely do not use marijuana while being treated with Edarbyclor.
Excessive sweating, diarrhea, or vomiting can increase the risk of dizziness or a serious loss of body water (dehydration). Report persistent diarrhea or vomiting to your doctor. To prevent dehydration, drink plenty of fluids unless your doctor directs you otherwise.
If you have diabetes, Edarbyclor may affect your blood sugar. So you need to check your blood sugar as often as directed and share the results with your doctor while using Edarbyclor. Your doctor may need to adjust your diabetes medication, exercise program, or diet accordingly.
Edarbyclor can affect your potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult your doctor.
Edarbyclor may make you more sensitive to the sun. Limit the time you spend in the sun, use sunscreen, and wear protective clothing outdoors while using Edarbyclor.
Before surgery, tell your doctor or dentist that you are being treated with Edarbyclor.
Older adults may be more sensitive to the side effects of Edarbyclor, especially dizziness and change in the amount of urine (kidney problems).
Edarbychlor is not recommended for women during pregnancy. Edarbyclor can cause serious (possibly fatal) harm to an unborn baby if used during pregnancy. Therefore, it is important to avoid pregnancy while taking Edarbyclor. Consult your doctor for more details and to discuss using reliable forms of birth control while taking Edarbyclor. If you are planning to become pregnant, become pregnant or think you may be pregnant, tell your doctor right away.
We do not currently know if azilsartan passes into breast milk. Chlorthalidone passes into breast milk. Consult your doctor before breast-feeding while using Edarbyclor.

Drug interactions can change the way Edarbyclor works or increase your risk of serious side effects. Make a list of all the medicines you take (including prescription/over-the-counter drugs and herbal products) and share it with your doctor. Do not start, stop, or change the dose of any medicine while you are using Edarbyclor, without your doctor's approval.
Some drugs that may interact with Edarbyclor drugs include: Aliskiren, cisapride, dofetilide, lithium, drugs that can increase the level of potassium in the blood (e.g. ACE inhibitors including benazepril/lisinopril, drugs birth control containing drospirenone).
Some medicines have ingredients that can increase your blood pressure, thereby reducing the effectiveness of Edarbyclor. Tell your doctor what products you are taking and ask how to safely use them with Edarbyclor (especially cough and cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). .

Edarbyclor may interfere with certain laboratory tests, possibly causing false test results. Make sure laboratory staff and all your doctors know you use Edarbyclor.

If you or someone else has overdosed on Edarbyclor and has severe symptoms such as fainting or difficulty breathing, call 911 immediately. Edarbyclor overdose symptoms may include: Severe dizziness, fainting.
If you miss a dose of Edarbyclor, take it as soon as you remember. If it is almost time for your next dose of Edarbyclor, skip the missed dose. Take your next dose of Edarbyclor at the usual time, do not take a double dose of your usual dose to make up for a previously missed dose.

Store Edarbyclor at room temperature, in its original packaging, away from light and moisture. Do not store Edarbyclor in another container, do not store it in the bathroom, and keep it away from children and pets.
Do not flush Edarbyclor down the toilet or down the drain unless instructed to do so. Dispose of this medication appropriately when it has expired or is no longer needed.

Reference source: webmd.com