Learn about the toothache drug Rodogyl

Rodogyl is an antibiotic produced in combination between two active ingredients spiramycine of the macrolide group and metronidazole of the nitro-5-imidazole group. The following article will introduce you to the effects of Rodogyl and some notes when using this drug.

Rodogyl has antibacterial activity of spiramycine antibiotics, so it is effective against bacteria that often cause oral diseases such as: Non-D Streptococcus, Bordetella pertussis, pneumococcus, meningococcus, Chlamydia, Actinomyces, Mycoplasma , Corynebacterium. On the other hand, gram-negative aerobic bacilli will be resistant to this antibiotic.
In addition, Rodogyl also has antibacterial activity of metronidazole, so it is able to kill some bacteria such as obligate anaerobic bacilli including: Clostridium, Bifidobacterium bifidum, C. perfringens, Eubacterium, Pneumosintes, Bacteroides fragilis , Melaninogenicus, Fusobacterium, Veillonella, Peptococcus, Peptostreptococcus. Bacteria belonging to the group of facultative anaerobic bacilli are resistant to this antibiotic.
Therefore, the combination of two individual active ingredients will produce a drug that has a synergistic effect against some susceptible strains of bacteria.

Rodogyl is indicated on the basis of its antibacterial activity and pharmacokinetics. Usually, the doctor can prescribe it for treatment in cases of acute, chronic or recurrent oral sinus infections such as:
Tooth abscess, periodontitis, gingivitis, inflammation, inflammation of the tissue. cell . Gingivitis, periodontitis. Inflammation of the parotid or submandibular salivary glands. Prophylaxis against local infection after oral procedures. Some contraindications to the use of Rodogyl include:
Patients with a history of hypersensitivity to imidazole and/or spiramycine and/or excipient cochenille A. Patients with gluten intolerance or sensitivity. Children under 6 years old because the dosage form of the drug is not suitable for use in this age group.

For adults, the usual dose is about 4-6 tablets per day, divided into 2-3 oral doses. In some severe cases, the dose can be increased up to 8 tablets per day.
For children, depending on age, the dose may be different such as:
Children from 6 to 10 years old: 2 tablets/day Children from 10-15 years old: 3 tablets/day divided into 3 times. Some notes when using Rodogyl drugs such as:
Pregnant women should avoid taking Rodogyl in the first 3 months of pregnancy because the drug can cross the blood-placental barrier. Avoid using Rodogyl while breastfeeding because metronidazole and spiramycine can pass into breast milk. The drug should be discontinued when symptoms such as loss of balance or dizziness occur. There is a risk of aggravating psychiatric symptoms in patients with stable or progressive CNS or peripheral neuropathy. Do not use alcohol while taking the drug because it can cause antabuse effect. The above information is for reference only. Its use in treatment should be under the direction of a specialist.

Reference sources: dieutri.vn, hellobacsi.com