Note when using oral antifungal drugs during pregnancy

Vaginal thrush is a common disease, especially during pregnancy, this condition is easy to flare up, causing discomfort for pregnant women and affecting babies born by vaginal delivery. In severe cases of fungal infections, oral antifungals may be indicated, however, is this an adequate measure when there is a potential risk of miscarriage?

During pregnancy, a fungal infection is a small but common problem. Currently, there is no research showing that a yeast infection increases the risk of miscarriage. There will also be fungus.
The main causes of yeast infection in pregnant women:
When pregnant or taking antibiotics for pregnant women, Candida Albicans fungus has favorable conditions to multiply because the alkalinity in the vagina increases more than the acidity. , become a food source for pathogenic yeast bacteria; Vaginal discharge often increases during pregnancy, which is an ideal environment for fungi to reproduce; Increased estrogen levels during pregnancy are also responsible for fungal infections. Common symptoms of a fungal infection:
Severe vaginal itching; Vaginal pain; There is burning when urinating, vaginal lips are swollen; Milky white discharge; Pain during sex. Currently, there are many antifungal drugs used for pregnant women, Amphotericin B is a drug used intravenously, spinal injection, vaginally without affecting the fetus. However, they can cause anemia or hypokalemia, when used, need to be closely monitored to avoid affecting pregnant women.
Antifungal drugs are mainly taken orally and have certain effects on the fetus such as: Griseofulvin, Metronidazol, Nistatin, Fluconazole and itraconazole:

Currently, there are no specific studies showing the effects of mushrooms on the fetus. However, if the mother has a yeast infection and gives birth to a baby by vaginal delivery, the baby will also get the fungus and affect health.
Usually, when a pregnant woman is diagnosed with thrush, the doctor will base on her health status to prescribe topical and vaginal suppositories, this is a safe way to treat thrush at this time. If the fungal infection is too complicated, the doctor may prescribe antibiotics for pregnant women to treat the fungus. However, using antibiotics for pregnant women is often limited because of certain effects on the fetus.
The use of oral antifungal drugs during pregnancy is generally not recommended because of the high risk of miscarriage and stillbirth.

In case of using oral antifungal drugs during pregnancy, pregnant women should note that they should not use the drug in the first 3 months of pregnancy; Oral antifungal drugs can only be used during pregnancy when prescribed by a specialist, taking the drug at the correct dose and prescribed time; During the use of the drug, if you see unusual phenomena such as digestive disorders, nausea, pregnant women need to go to the nearest hospital or medical center for examination; Some oral antifungal drugs interact with other drugs, so pregnant women should bring the prescription they are using to the doctor to check; Oral antifungal drugs for pregnant women have certain effects on the fetus, have a high risk of miscarriage and fetal malformations, should be carefully considered before use. In summary, if you have a yeast infection during pregnancy, you should treat it early and actively coordinate with your doctor to achieve the best results. In the event that oral antifungal drugs must be used during pregnancy, the benefits and harms of it should be weighed, and the pregnant woman may choose to have a cesarean section to avoid infecting the baby and to treat it after the birth of the baby. In particular, to prepare for a healthy pregnancy, both husband and wife should have their reproductive health checked 3-5 months before becoming pregnant.

The wife should:
Get vaccinated before pregnancy (especially against rubella because rubella in pregnancy is extremely dangerous ) Genetic testing to screen for genetic diseases before pregnancy Check for gynecological infections Avoid affecting the health of the mother and the fetus Especially women over 35 years old who want to become pregnant (especially if they have never been pregnant) will have to have a very detailed health check because pregnancy at this age is common. problems: Ovarian failure, premature birth, higher risk of birth defects, placenta previa, preeclampsia. The husband should:
Check reproductive health, detect testicular atrophy, physiological weakness, weak sperm... Sexually transmitted diseases, especially those that cannot be cured, are extremely dangerous. Vinmec currently has many comprehensive health care programs for couples, pregnant mothers and their unborn babies, including basic pre-marital examination packages, advanced pre-marital examination packages, and maternity packages. . Vinmec has a team of experienced doctors in the fields of obstetrics and gynecology, IVF, stem cells, gene technology, capable of synchronously and comprehensively deploying the most advanced assisted reproductive techniques today.
For specific information about fertility and maternity packages at Vinmec, please contact the hospitals and clinics of Vinmec health system nationwide.