Notes when using cinnarizine to treat vestibular disorders

Cinnarizine in addition to treating vestibular disorders is also effective in the treatment of circulatory disorders and motion sickness. However, there should also be cautions when using Cinnarizine to avoid unwanted side effects.

The vestibule is considered an organ of the nervous system, with an anatomical position located behind the cochlea on both sides and holds an extremely important role in the body that is maintaining balance when performing postures. , gait, coordination of movements of body parts such as eyes, head, trunk.
When people perform any movement such as walking, standing, running, bending, turning... the vestibular system also moves along and balances the body when performing these movements. Once the body has vestibular disorders, there will be some manifestations such as dizziness, lightheadedness, lightheadedness, ringing in the ears, nausea, loss of balance when performing postures, leading to a very easy fall. when moving.

Vestibular disorders, if not treated promptly and properly, are very likely to recur many times and tend to get worse, greatly affecting the patient's quality of life. In these cases, vestibular disorders should be used to control these symptoms. Currently, Cinnarizine is the drug of choice for treating the symptoms of vestibular disorders as well as preventing motion sickness.

Cinnarizine is a group of H1 antihistamines with the effect of blocking receptors in the last organs of the vestibular system, thereby inhibiting the production of histamine and acetylcholine. In addition, Cinnarizine is also a calcium antagonist, so it inhibits the contraction of smooth muscle cells in the blood vessels, also known as a calcium blocker.
Cinnarizine is indicated in the following cases:
Patients with vestibular disorders with symptoms such as dizziness, lightheadedness, tinnitus, nystagmus, nausea, vomiting... People who are intoxicated vehicle Patient has migraine syndrome Patient has symptoms caused by cerebrovascular damage such as dizziness, vertigo, tinnitus, nausea, memory loss, poor concentration. pathology related to peripheral circulatory disorders such as Raynaud's syndrome, claudication symptoms, nutritional disorders, symptoms of varicose ulcers, muscle spasms... Dose of Cinnarizine for adults and children are prescribed as follows:
For adults Patients taking Cinnarizine to treat diseases of cerebral circulation: Cinnarizine 25mg x 1 tablet/time x 3 times/day.
Patients taking Cinnarizine to treat symptoms of vestibular disorders such as dizziness, lightheadedness: Cinnarizin 25mg x 1 tablet x 3 times/day
Patients taking Cinnarizine in peripheral circulatory disorders: Cinnarizine: 25mg x 2 - 3 tablets
People who use Cinnarizine to prevent motion sickness: Cinnarizin 25mg x 1 tablet 2 hours before meals.
For children Usually the dose of Cinnarizine in children is reduced by half compared to the dose in adults and is taken after a child's meal for the most effective medicine.

Some side effects that Cinnarizine causes for users are:
Digestive system disorders, drowsiness... but these symptoms usually tend to be relieved when continuing to use Cinnarizine. Extrapyramidal symptoms such as spasticity, slow movement, movement disorders including dancing, chorea, myoclonic tremor, etc., are especially common when using Cinnarizine on humans. Elderly, if not handled promptly, it will tend to be more severe. Headache, dry mouth, increased sweating, weight gain Some notes when using Cinnarizine are:
Cinnarizine is recommended to be used most effectively after meals to reduce stomach irritation because the drug can In the case of Cinnarizine used for the purpose of anti-motion sickness, it should be taken 2 hours before meals for maximum effect. However, patients also need to be careful when taking Cinnarizine that is not to take the drug with alcohol or other substances that can inhibit the central nervous system, tricyclic antidepressants because in these cases will may increase the sedative effect of the drug. Patients who are allergic to the ingredients of the drug as well as those who experience disorders in porphyrin metabolism should not arbitrarily use the drug without the consent of the treating doctor. Because the drug can cause drowsiness due to its sedative effect, users should be careful to avoid taking Cinnarizine while doing tasks that require mental alertness such as driving, working at height or do work related to machine operation. Cinnarizine should not be used in elderly patients because of the potential for extrapyramidal symptoms. Pregnant women who want to use Cinnarizine should consult their treating doctor before using. potentially aggravating this condition. Patients experiencing digestive disorders, somnolence can take Cinnarizine in gradually increasing doses and if necessary, the drug can be stopped when the symptoms get worse. The drug should be stored at an average temperature, below 30°C to avoid losing its biological effects.

Although Cinnarizine is a fairly well tolerated and highly effective drug among vestibular disorders as well as a number of other diseases, the drug can still leave some side effects. want to affect the patient's health, so it is necessary to be careful when using Cinnarizine and it is best to have a doctor's prescription before taking the drug, and at the same time follow the instructions as the way the doctor prescribes it. consulting value.
Vinmec International General Hospital with a system of modern facilities, medical equipment and a team of experts and doctors with many years of experience in medical examination and treatment, patients can rest assured to visit examination and treatment at the Hospital.