The effect of the drug Gramadol

Gramadol's effect is known to relieve pain from acute to severe conditions. So what should be noted when using the drug, does Gramadol cause any side effects?

Gramadol drug belongs to the group of pain relievers, is prepared in the form of hard capsules and the main ingredients include Paracetamol (325mg content) and Tramadol (37.5mg content). Specific effects of each substance are as follows:
Paracetamol: Reduce pain, reduce fever. Tramadol: Synthetic analgesia through central nervous system depression. This active ingredient has the same addictive potential as morphine. Gramadol is used for the relief of acute to severe pain in adults. Gramadol is contraindicated in people who are allergic to Paracetamol, Tramadol or any of its ingredients, who have acute alcohol intoxication and severe liver failure.

Gramadol is for use only in children 16 years of age and older and adults.
Dosage: 2 tablets / time, 3-4 times / day, each time used 4-6 hours apart. Maximum dosage: 8 tablets/day. Duration of treatment: No more than 3 days. Note, people with renal failure and creatinine clearance less than 30mL/min should not take more than 2 tablets in 12 hours. Take the medicine after eating and do not drink alcohol while taking the medicine.
Do not overdose on Gramadol because it can cause convulsions, respiratory depression, fatigue, arrhythmia, difficulty breathing, altered perception or even loss of consciousness, drowsiness, narrowed pupils, abdominal pain, nausea and vomiting. If any of the above symptoms are observed, the patient should seek immediate medical attention.

The composition of the drug Gramadol may cause some unwanted side effects such as:
Paracetamol: Allergies, skin rash, urticaria, possibly with fever. Tramadol: For the digestive system, Tramadol may cause abdominal pain, dry mouth, nausea, vomiting, bloating, indigestion, constipation, or diarrhea. For the nervous system, Tramadol can cause headache, dizziness, nervousness, anxiety, hallucinations, tremor, increased tone. Some other side effects caused by Tramadol in Gramadol but more rarely such as orthostatic hypotension, heart failure, increased liver enzymes, epidermal dermatitis, anaphylaxis, Stevens-Johnson syndrome. If you notice any of the above symptoms, tell your doctor immediately.

The use of the drug Gramadol should be noted in some groups of subjects and drug interactions as follows:
Gramadol may interact with other drugs containing Paracetamol or Tramadol, anesthetics, sedatives, depressions of the nervous system. CNS, ... Pregnant women should not use Gramadol because it can affect the development of the fetus, increase the risk of death, cause respiratory failure, convulsions in the newborn. Women who are breastfeeding should also not take Gramadol because the drug can be excreted in breast milk, causing drowsiness, respiratory depression, and even death in newborns, because the child is not able to metabolize get Tramadol. People who drive or operate machinery should not take Gramadol because the side effects caused by the drug may affect work such as dizziness, dizziness, visual disturbances. Gramadol helps relieve pain effectively, but do not take more than 8 tablets a day and up to 3 days of treatment, because the active ingredient Tramadol in the drug can be addictive like morphine and some other unwanted side effects.