Uses of Acefdrox

Acefdrox 250 is a brand name oral suspension of the antibiotic Cefadroxil. Acefdrox 250 is used to destroy susceptible bacteria that cause infections in certain parts of the body.

Acefdrox 250 is a drug belonging to the group of drugs used to treat parasites, anti-infectives, antivirals, antifungals. The main active ingredient in the drug is Cefadroxil - a first generation Cephalosporin antibiotic.
Acefdrox 250 comes in the form of oral suspension, packaged in 30ml bottles, the concentration of Cefadroxil in Acefdrox is 250mg per 5ml of the drug.

Acefdrox 250 is used to treat certain infections caused by bacteria. The drug's mechanism of killing bacteria is to inhibit the synthesis of components of the plasma membrane and inhibit the final step in the biosynthesis of the bacterial cell wall.
The drug has bactericidal effect on many types of Gram-positive and Gram-negative bacteria.
Sensitive aerobic Gram-positive bacteria include: Streptococcus pneumoniae, Propionibacterium acnes, Corynebacterium diphtheria, methicillin-susceptible Staphylococcus and Streptococcus pyogenes.
Sensitive aerobic Gram-negative strains include: E. coli, Neisseria gonorrhoeae, Klebsiella pneumoniae, Branhamella catarrhalis, Pasteurella.
Anaerobic bacteria like Fusobacterium. Prevotella.
Bacterial strains that are moderately sensitive to the drug such as: Citrobacter koseri, Proteus mirabilis, Haemophilus influenzae, Clostridium perfringens, Peptostreptococcus.
Acefdrox 250 is indicated for mild and moderate infections caused by susceptible bacteria, such as:
Uncomplicated urinary tract infections (nephritis - acute pyelonephritis, inflammation of the pyelonephritis. chronic pyelonephritis, cystitis, urethritis.) Respiratory infections: Bronchopneumonia, lobar pneumonia, acute/chronic bronchitis, lung abscess, pleurisy, purulent pleurisy , Ear, nose and throat infections: Tonsillitis, pharyngitis, sinusitis, otitis media. Skin and soft tissue infections: cellulitis, abscess, ulceration due to prolonged lying, boil disease, lymphadenitis, mastitis, erysipelas. Other infections: osteomyelitis, septic arthritis. First-generation cephalosporins are second-line agents for the treatment of Gram-positive bacteria, with penicillins of first choice preferred.
Sometimes, it is also given to certain patients who are allergic to penicillin who have heart disease and are undergoing dental procedures or in the upper respiratory tract (nose, mouth, throat), to prevent infection. heart valve.

Dosage for adults from 1 to 2 g per day, can be taken once or divided into 2 oral doses.
For children with urinary tract infections: 30 mg per kg body weight per day, divided equally into 2 oral doses.
For the treatment of pharyngitis, tonsillitis, impetigo, skin and soft tissue infections also use a dose of 30 mg per kg body weight per day, taken once or divided into 2 uses.
When using the drug to treat the condition caused by beta-hemolytic streptococcal infection, it should be taken for at least 10 days.
In people with renal failure, depending on the creatinine clearance ClCr, the doctor will give the appropriate dose adjusted.
Take the drug suspension with or without food at the same times each day to avoid missing doses.
Use the medicine exactly as directed by the doctor, pharmacist, if there is any problem, please confirm. Do not take more, less or more often than the recommended dose and route of administration.
Take Acefdrox 250 with food to reduce nausea and upset stomach.
Shake the oral suspension well before each use to mix the medicine well.
You will start to feel better within the first few days of treatment. If symptoms do not improve or get worse, call your doctor.
Continue taking the antibiotic Acefdrox 250 until the prescription is complete, even if you feel better. If the medication is stopped too soon or the dose is skipped, the infection may not be completely treated and the bacteria may become resistant to the drug.
If you forget to take a dose, make up for it as soon as you remember. But if it is almost time for the next dose, skip the missed dose and use the next dose as usual, do not increase it on your own. double to make up for it.
When drug overdose, most patients only have nausea, vomiting, diarrhea. However, neuromuscular hypersensitivity and convulsions may also occur, especially in patients with renal failure.

Culture and susceptibility testing of bacteria should be carried out, and antibiograms should be established before and during the treatment of infectious conditions.
In patients with renal insufficiency or suspected renal failure, the elderly should conduct a renal function test before taking the drug.
Tell your doctor before you are prescribed Acefdrox 250 if you are or have ever had the following conditions:
Allergy to any component of this oral suspension or to antibiotics of another Cephalosporin class , the antibiotic Penicillin, or any other medicine. Ever had gastrointestinal disease (GI, especially colonic mucosal swelling, also known as colitis) Kidney disease. There are no adequate studies on the side effects of the drug in pregnant women, so it should only be used when clearly needed. If you discover that you are pregnant during use, notify your doctor immediately.
The Cefadroxil component in this oral suspension is excreted in low concentrations in breast milk. Therefore, it is necessary to be cautious when using the drug for nursing mothers, pay attention to when children have symptoms of thrush, diarrhea, and rash.

5.1 Drug Interactions While taking this medicine, give your doctor a complete list of medicines you are taking, taking note of some of the medicines listed below such as:
Cholestyramine Probenecid Furosemid Aminoside antibiotics Vaccines typhoid 5.2 Adverse effects of Acefdrox 250 The antibiotic Acefdrox 250 can cause diarrhea, which may be indicative of a new infection. If you have diarrhea with watery or bloody stools, call your doctor before taking anti-diarrheal medicine.
Get emergency medical help if you have signs of a serious allergic reaction such as: hives, difficulty breathing, swelling of your throat, face, lips, tongue.
Acefdrox 250 can cause serious side effects. Call your doctor right away if you have:
Severe stomach pain, bloody stools; fever, chills, body aches, flu symptoms; pale skin, easy bruising, unusual bleeding; Epilepsy ; Weakness, confusion; Dark urine, yellow skin/eyes; kidney problems--little or no urinating, swollen feet, fatigue, trouble breathing. Common adverse drug reactions may include:
Diarrhea; Stomachache; Itching or unusual vaginal discharge. In addition to the necessary effect of the drug to cure the disease, some unwanted effects may occur when using Acefdrox 250. Although not all of these side effects are possible, if they do happen you may need medical attention.