Uses of Augtipha 281, 25mg

Pharmaceutical name: Augtipha 281.25mg
Classification: Drug
Registration number: VD-22213-15
Drug group: Antiparasitic, anti-infective, antiviral, antifungal medicine
Manufacturer: Company Tipharco Pharmaceutical Joint Stock Company
Ingredients: Amoxicillin (in the form of amoxicillin trihydrate) 250mg/pack of 3.8g; clavulanic acid (as potassium clavulanate) 31.25mg/pack of 3.8g
Drug form and strength:
Dosage form: Powder for oral suspension Packing: Box of 12 packs x 3.8g Content: Need to look carefully Drug form and strength are indicated on the product packaging or in the instruction leaflet for exact information on the drug form and content in the product.

2.1 Indications Augtipha 281, 25mg is indicated in the treatment of:
Otitis media, Tonsillitis, Pharyngitis, Laryngitis, Bronchitis, Sinusitis, Pneumonia, Urinary tract infections, Skin infections, Gonorrhea. 2.2 Dosage and way of use How to use:
Each drug, pharmaceutical product is produced in different forms and has different ways of using according to the route of administration. The usual routes of drug administration by drug form are: oral drugs, injections, external drugs and suppositories.
Carefully read the instructions on how to take Augtipha 281.25mg above from the drug user manual, do not arbitrarily use the drug by other routes not stated in the instruction sheet for using Augtipha 281.25mg.
Instructions on how to use Powder for oral suspension:
First tap the bottle so that the entire amount of powder flows to the bottom of the bottle. Pour cooled boiled water into the bottle to the mark marked on the bottle, then shake vigorously to disperse the powder into the water. Add water if necessary to adjust the suspension volume to the marked mark. Shake well before use. Dosage:
The usual dose is 250 mg - 500 mg (calculated on amoxicillin), every 8 hours. Children up to 10 years old can be given a dose of 125 - 250mg, every 8 hours. Children under 20kg usually take a dose of 20-40 mg/kg body weight/day. Higher doses, taken as a single dose or in short bursts, are used in some conditions:
3g dose, repeated after 8 hours to treat periodontal abscess or repeated after 10-12 hours for treatment. Treatment of uncomplicated urinary tract infections. To prevent endocarditis in susceptible individuals, a single dose of 3g should be given 1 hour before a procedure such as tooth extraction. Use a high-dose regimen of 3g amoxicillin twice a day for patients with severe or recurrent respiratory tract infections. If necessary, children 3-10 years old with otitis media can be given 750mg/time, twice daily, for 2 days. Dosage of Augtipha 281.25mg for adults
The dosage regulations are usually intended to guide adult subjects for oral administration. Dosage for other routes is specified in the leaflet. Do not change the dose on your own without consulting your doctor or pharmacist.
Dosage of Augtipha 281.25mg for children
Differences between children and adults such as pharmacokinetics, pharmacodynamics, side effects... especially children are not allowed to be brought in. clinical trial before the marketing authorization of a new drug. Therefore, using this drug for children should be very careful even with drugs that have not been warned.
2.3 Missed dose, overdose and management Overdose/ Management:
Symptoms of overdose may include: abdominal pain, vomiting, diarrhea, rash, hyperactivity, drowsiness.
In case of emergency or overdose with dangerous manifestations, call 911 Emergency Center or go to the nearest local Medical Facility. Relatives need to provide the doctor with the prescription they are taking, the medicines they are taking, including prescription and non-prescription drugs.
Missed dose:
In case you miss a dose while taking the medicine, take it as soon as possible (usually it can be taken 1-2 hours before the time ordered by the doctor). However, if it is almost time for your next dose, skip the missed dose and take your next dose at the prescribed time. Be careful not to double the prescribed dose.

Augtipha 281.25mg side effects:
Diarrhea, stomach pain, vomiting, skin rash, itching, hives, difficulty breathing or swallowing, wheezing, itching and vaginal discharge, yellow skin or eyes. Amoxicillin and Clavulanic acid can cause other side effects. Call your doctor if you have any unusual problems with your medication. Other side effects:
It should be noted that this is not a complete list of all side effects of Augtipha 281.25mg. In the process of use may occur other side effects that have not been shown or have not been studied. If there are any other side effects of Augtipha 281.25mg that are not specified in the instructions for use, please consult your doctor or pharmacist.

Contraindications
HRT mode is not applicable if one of the following conditions is met. Treatment must be discontinued if during the use of the drug any of the following phenomena:
Pregnancy and lactation. Undiagnosed vaginal bleeding. Known or suspected breast cancer. There are elements of precancerous or suspected cancer due to the effects of sex steroids. Have a history of or current liver tumor (benign or malignant). Have serious liver disease. Active deep vein thrombosis, thromboembolic disorders or a history of these conditions. Severe hypertriglyceridemia. History of hypersensitivity to any component of Estradiol. Note before taking Augtipha drug 281.25mg
Patients are sensitive to Amoxicillin, Clavulanic acid and Penicillin group antibiotics. Patient has a history of cholestatic jaundice/liver dysfunction. Patients with severe renal impairment (creatinine clearance < 30ml/min) and patients on hemodialysis. Pregnancy: There are no adequate and well-controlled studies in pregnant women. Use during pregnancy only when clearly needed. Lactation: Amoxicillin is excreted in breast milk; Therefore, caution should be exercised when administering the drug to a nursing mother. Children: Safety and efficacy have been established for pediatric patients weighing ≥ 40 kg who can swallow tablets. Elderly: Renal function should be monitored. Patients with renal impairment: Contraindicated in patients with creatinine clearance < 30 ml/min and in hemodialysis patients. Hepatic Impairment: Use caution when determining dose and monitor liver function at regular intervals. Note to use Augtipha 281.25mg during pregnancy
General note during pregnancy: The drug used during pregnancy may cause adverse effects (miscarriage, teratogenicity, fetal malformations). ..) to any stage of pregnancy, especially the first trimester. Therefore, it is best not to use the drug for pregnant women. In the case of mandatory use, it is necessary to consult carefully with your doctor, pharmacist before making a decision.
Note taking Augtipha drug 281.25mg during lactation
General note during lactation: The drug can be passed to the baby through breastfeeding. It is best not to or limit the use of the drug during breast-feeding. Many drugs have not yet fully determined the effects of drugs during this period, so mothers need to carefully read the instructions for use and consult with doctors and pharmacists before deciding to use drugs.

When using two or more drugs at the same time, drug interactions often occur, leading to antagonism or synergism.
Drug interaction Augtipha 281.25mg with other drugs
Probenecid: Probenecid reduces the renal tubular secretion of Amoxicillin. Concomitant use of Probenecid with Amoxicillin and Clavulanic acid may increase blood levels of Amoxicillin. Concomitant use is not recommended. Oral Anticoagulants: Concomitant use of oral anticoagulants with Amoxicillin and Clavulanic acid may result in abnormal prolongation of Prothrombin time. Dosage of oral anticoagulants should be adjusted. Allopurinol: Concomitant administration of Allopurinol with Amoxicillin significantly increased the incidence of rash in patients. Oral Contraceptives: Amoxicillin and Clavulanic acid may affect the intestinal microflora, resulting in decreased estrogen reabsorption and decreased effectiveness of the combined Estrogen/Progesterone oral contraceptive. Amoxicillin can lead to a false-positive reaction in a urine glucose test. Drug interaction Augtipha 281.25mg with food and drink
When using the drug with foods or alcohol, beer, tobacco... because the foods and drinks contain other active ingredients, so may have an antagonistic or synergistic effect on the drug. Read the instructions for use carefully or consult your doctor or pharmacist about taking Augtipha 281.25mg with food, alcohol and tobacco.
Preservation medicine:
Store below 30 degrees Celsius, avoid moisture. Keep Augtipha 281.25mg out of the reach of children and away from pets. Before taking Augtipha 281.25mg, it is necessary to check the expiry date indicated on the product packaging, especially for home-stored medicines.