Uses of Dixapim

The active ingredient cefepim in Dixapim is a semi-synthetic cephalosporin antibiotic, classified in the 4th generation with a broader antibacterial spectrum than previous generations. Cefepim exerts its antibacterial effect through its ability to inhibit the synthesis of mucopeptides in the bacterial cell wall. Bacterial strains susceptible to cefepime include:
Enterobacteriaceae Pseudomonas aeruginosa Haemophilus influenzae Neisseria gonorrhoeae Streptococcus and Streptococcus families Another outstanding feature of the active ingredient cefepime in Dixapim is that it is not degraded by bacterial beta-lactamases. gram negative, and its ability to act against gram-positive bacteria is also stronger than the antibiotics ceftazidime or ceftriaxone.
Deriving from the above mechanism of action, Dixapim is often used by injection to treat cases such as:
Pneumonia, bronchitis or diseases related to lower respiratory tract infections causing produced by susceptible strains of bacteria. Severe urinary tract infections, including those with complications. Skin structure infections Abdominal cavity infections Biliary tract infections Meningitis in children

The recommended dose of Dixapim in adults and children 12 years of age and older is as follows:
If the infection is mild to moderate: 0.5 - 1g injection every 12 hours. If the infection is severe: 2g injection every 12 hours. Maintain the therapeutic dose within these 7 to 10. In patients with underlying renal impairment, the dose of Dixapim must be adjusted based on creatinine clearance to ensure safety. Dixapim is administered by slow intravenous injection, deep intramuscular injection or intravenous infusion. Common solvents used to dilute the drug before injection or infusion are distilled water for injection, 0.9% sodium chloride solution, 5% glucose solution, 5% Ringer lactate and dextrose solution, ..
Before use When using the drug, it is necessary to observe with the naked eye whether the solution is precipitated or not. Precipitation is a warning sign that the quality of the drug is not up to the requirements, so it should be discontinued and destroyed.
Patients are not allowed to arbitrarily use Dixapim without the prescription of the doctor and the instructions of the medical staff.

Absolutely do not use Dixapim for patients who have ever been allergic to antibiotics of the cephalosporin group, penicillin or other betalactam groups.
Dixapim is also contraindicated in patients with a history of hypersensitivity to other excipients included in the formulation.

Patients treated with Dixapim may experience side effects such as:
Pain at the injection site Nausea, diarrhea, abdominal pain Taste disturbances Pseudomembranous colitis Decreased white blood cell count in the blood count Rash, pruritus, urticaria Genital itching Vaginal infection If the side effects are severe enough to affect your quality of life, you should tell your doctor to get the most accurate advice. .

Because Dixapim is incompatible with drugs such as aminoglycosides, metronidazol, vancomycin, aminophylin, so during intravenous infusion, these drugs should be used separately, avoiding simultaneous infusion.
Dixapim when combined with furosemide increases the risk on hearing, so this combination should be limited.