Uses of dorotor 20mg

1.1. What is Dorotor 20mg? Dorotor 20mg belongs to the group of drugs for treating dyslipidemia, with registration number VD-20064-13, manufactured by Domesco Medical Import-Export Joint Stock Company - Vietnam.
Dorotor 20mg drug has the following ingredients:
Main active ingredient: Atorvastatin calcium trihydrate 20mg. Excipients: Lactose, Povidone K30, Croscarmellose sodium, Calcium hydrogen phosphate dihydrate, Hydroxypropyl methyl cellulose 15cP, Magnesium stearate, Polyethylene glycol 6000, Talc, Hydroxypropylmethyl cellulose 6cP, Titanium dioxide, Color Sicovit red. Dorotor 20mg is prepared in the form of film-coated tablets, blisters of 10 tablets, boxes of 2 blisters. The drug is recommended for use by people 18 years of age and older.
1.2. What does Dorotor 20mg do? Dorotor 20 mg drug is an ETC drug used in the following cases:
Treatment of dyslipidemia Active ingredient Atorvastatin in Dorotor 20 mg is indicated as an adjunct to dietary therapy to reduce total cholesterol and cholesterol levels. LDL, apolipoprotein B (apo B) and triglycerides and to increase plasma HDL-cholesterol in patients with primary hypercholesterolemia and mixed dyslipidemia, homozygous familial hypercholesterolemia and hypertriglyceridemia blood.
Primary prevention (level I) of cardiovascular events -Second prevention (level II) of cardiovascular events Prevention of cardiovascular events in people with diabetes Reduces progression of coronary atherosclerosis

2.1. How to take Dorotor 20mg Dorotor 20mg is indicated for oral use. A single dose can be taken at any time of the day, with a meal or on an empty stomach.
Drugs for adults. 2.2. Dosage of Dorotor 20mg Initial dose 10mg, once daily. Adjust dose every 4 weeks, if needed and if tolerated. Maintenance dose 10mg - 40mg/day. If necessary, the dose can be increased, but not more than 80mg/day. * Note: Patients taking atorvastatin in combination with the following drugs:
When used in combination with amiodarone, the dose should not exceed 20mg/day. When used in combination with ciclosporin, the maximum dose is 10mg, once a day. When clarithromycin is used in combination, start at 10 mg once a day and up to a maximum of 20 mg once a day. When itraconazole is used in combination, start at 10 mg once a day and up to a maximum of 40 mg once a day. Caution should be taken when using Dorotor 40mg in combination with (ritonavir + lopinavir) at doses above 20mg, once a day. Do not take more than 20mg of atorvastatin/day when co-administered with (darunavir + ritonavir); fosamprenavir; (fosamprenavir + ritonavir); (saquinavir + ritonavir). Do not exceed 40 mg of atorvastatin/day when used with nelfinavir. * It is recommended to start treatment with the lowest effective dose, then, if necessary, to adjust the dose according to individual needs and response by increasing the dose at intervals of not less than 4 weeks and Adverse drug reactions must be monitored, especially adverse reactions to the muscular system.
Handling when missed dose: Take Dorotor 20mg as soon as you remember. However, if the interval between the next dose is too short, skip the missed dose and resume the dosing schedule. Do not take a double dose to make up for a missed dose.
Treatment of overdose: If an overdose occurs, symptomatic treatment and support should be given as necessary. Because the drug is strongly bound to plasma proteins, hemodialysis is not expected to significantly increase clearance of atorvastatin. In the event of an emergency, call 911 immediately or go to the nearest local health station.

Patients who are allergic to the main active ingredient Atorvastatin or any of the excipients listed above of Dorotor 20mg Patients with hypersensitivity to HMG-CoA reductase inhibitors Liver disease or elevated transaminases unexplained persistent serum sickness. Women who are pregnant or breastfeeding.

It is recommended that liver enzyme testing be performed prior to initiating statin therapy and in cases where clinical indications require testing thereafter. Caution should be exercised when using the drug in patients who drink a lot of alcohol and/or have a history of liver disease. Use of lipid-lowering agents is merely a multifactorial intervention in patients at increased risk for hypercholesterolemic atherosclerotic disease. Lipid-lowering drugs should be used in conjunction with a reasonable diet low in saturated fat and cholesterol and only used when there is no adequate response to diet and other non-pharmacological measures. Before treatment with Atorvastatin, it is necessary to rule out secondary causes of elevated cholesterol (eg, uncontrolled diabetes, impaired thyroid function, nephrotic syndrome, dysproteinemia, obstructive liver disease, alcoholism, etc.). ..) and need to check blood lipids. Consider creatine kinase (CKMB) monitoring for: Impaired renal function, hypothyroidism, personal or family history of hereditary myopathy, history of myopathy due to previous statin or fibrate use , history of liver disease and/or heavy alcohol consumption, elderly patients (> 70 years) with risk factors for rhabdomyolysis, the possibility of drug interactions, and some special patient populations. Atorvastatin may increase the effects of warfarin. Prothrombin time should be determined before initiating atorvastatin and regularly monitored during the initial phase of treatment to ensure that there is no significant change in prothrombin time. Avoid concomitant use and limit the dose of atorvastatin when used concomitantly with HIV and hepatitis C virus (HCV) drugs because of the potential for increased risk of muscle damage, most seriously rhabdomyolysis. , kidney failure leads to kidney failure and can be fatal.

Common:
Digestive system: flatulence, abdominal pain, nausea, diarrhea, constipation. Central nervous system: dizziness, headache, blurred vision, insomnia, asthenia. Nervous - muscle and bone: Muscle pain, arthralgia. Uncommon:
Neuromuscular and skeletal: Myopathy. Skin: Skin rash. Respiratory system: Rhinitis, sinusitis, pharyngitis, cough. Rare:
Neuromuscular and skeletal: Myositis, rhabdomyolysis, leading to acute renal failure secondary to myoglobinuria. * Other side effects:
Cognitive decline (dementia, confusion,...) Increased blood sugar. Increased HbA1c.

Store in a cool, dry place, at a temperature not exceeding 30°C, in the original packaging and protected from light. Do not leave medicine in the bathroom or refrigerator. Keep out of reach of CHILDREN.