Uses of Esomarksans
Esomarksans is a medicine for the treatment of stomach diseases, with the main ingredient being Esomeprazole sodium. To better understand what Esomarksans has as well as unwanted effects during drug use, you can refer to the article below.
1. Indications - Uses of Esomarksans
Indications: Esomarksans drug is used to treat cases of gastric and duodenal ulcers, reflux esophagitis with ulcers and Zollinger - Ellison syndrome that do not respond to oral therapy.
Uses:
Active ingredient Esomeprazole is a proton pump inhibitor, with the ability to bind 97% to plasma proteins. Esomeprazole sodium is completely metabolised via the cytochrome P450 (CYP) system, which is dependent on the polymorphic CYP2C19 enzyme and forms the hydroxy and desmethyl metabolites of Esomeprazole sodium. The plasma half-life of Esomarksans is approximately 1.3 hours after repeated once-daily dosing. Esomeprazole sodium has no tendency to accumulate with once-daily dosing and is completely eliminated from plasma between doses. Esomarksans is excreted in the urine as metabolites, the remainder in the feces. Esomeprazole sodium is the S-isomer of omeprazole, which reduces gastric acid secretion by a specific mechanism of action. Esomarksans is a specific inhibitor of the acid pump in parietal cells. Esomeprazole sodium is a weak alkaline, H+K+-ATPase (acid pump) inhibitor and inhibits both basal and stimulated secretion. In addition, the drug also affects the secretion of gastric acid.
2. Dosage - How to take Esomarksans
How to use:
The drug is prepared in the form of a powder for injection, packaged in 2 ampoules: 01 tube containing Esomeprazole and 01 tube containing 10ml solvent. Dilute the ampoule containing esomeprazole with 10 ml of solvent. Then slowly intravenously. Dosage:
Gastritis - duodenal ulcer: Slow intravenous injection, dose 40mg/day. Zollinger-Ellison syndrome adjust dose according to patient response. For patients with liver failure, mild and moderate renal impairment, the elderly when taking Esomarksans do not need to adjust the dose.
3. Contraindications to the use of Esomarksans
Do not administer to patients who have had a hypersensitivity reaction to any of its ingredients.
4. Esomarksans drug interactions
In the process of taking Esomarksans, it is necessary to note the drug interactions:
Diazepam . Phenytoin. Warfarin.
Diazepam . Phenytoin. Warfarin.
5. Side effects when taking Esomarksans
Note the unwanted effects when using Esomarksans:
Headache. Diarrhea. Stomachache . Nausea, vomiting. Upper respiratory tract infection. Dizzy . Rash, urticaria. Constipation. A cough. Asthenia. Backache.
6. Overdose of Esomarksans and treatment direction
When using an overdose of Esomarksans, patients may experience symptoms including: Nausea, vomiting, abdominal bloating, gas, diarrhea, rash and allergies. In case of a strong reaction, the patient may go into anaphylaxis or have difficulty breathing, call 911 and take the patient to the hospital immediately.
7. Missed dose of Esomarksans and treatment
In case of forgetting a dose of Esomarksans: Esomarksans is a prescription drug prescribed by a doctor and taken by medical staff. If in case you suspect that you have missed a dose, please notify your doctor or any medical staff at the facility for timely feedback and treatment. Patients should absolutely not self-medicate without the prescription of a specialist.
In summary, Esomarksans is a gastrointestinal drug, treating diseases of peptic ulcer disease, severe gastroesophageal reflux disease, unresponsive to oral administration. Medicines are made according to the doctor's orders, to ensure safe drug use, correct dosage, correct indications and avoid other adverse interactions, patients need to strictly follow the doctor's instructions. If you have any further questions regarding Esomarksans, please consult your doctor/pharmacist for advice.