Uses of Givet 5

Givet 5 drugs are often used in the prevention and treatment of chronic bronchial asthma, prevention of bronchospasm due to exercise,... So what is Givet?

Givet 5 is formulated as a film-coated tablet, the main ingredient in each tablet is Montelukast (as Montelukast sodium) 5mg.
Montelukast belongs to the class of leukotriene receptor antagonists (these are substances that are capable of causing inflammation, they are released from many types of cells). Montelukast has anti-inflammatory properties, helping to improve inflammatory parameters of asthma, due to its ability to inhibit airway cysteinyl leukotriene receptors, thereby inhibiting bronchospasm.
Montelukast has a bronchodilator effect within 2 hours of oral administration, which has a synergistic effect with beta-agonist bronchodilation.
Givet-5 is indicated in the following cases:
Prophylaxis and treatment of chronic bronchial asthma in the elderly and children over 6 months of age: Prevention of daytime and nighttime asthma symptoms; Treatment of aspirin-sensitive asthmatic patients; Prophylaxis of exercise-induced bronchospasm. Relief of symptoms of allergic rhinitis : Seasonal allergic rhinitis in both adults and children 2 years of age and older; Seasonal and year-round allergic rhinitis in adults and children from 6 months of age. Givet 5 is contraindicated in cases of hypersensitivity to any of its components.

2.1. How to use the drug Givet 5 Givet 5 medicine is used orally, once a day, when to take the medicine:
Asthma is usually recommended to take it at night. Allergic rhinitis: Depending on the needs of each patient. Both asthma and allergic rhinitis are recommended for evening use. This medicine can be taken with or without food. Patients only stop taking the drug when prescribed by the doctor, need to continue taking Givet 5 even though the asthma is under control. Givet 5 can be combined with other asthma medicines.
2.2. Dosage The dose of Givet 5 should be according to the doctor's prescription. Recommended dosage of Givet 5:
From 15 years old and up: Use 2 tablets/time. From 6-14 years old: Use 1 tablet/time. Under 6 years old: Use the form of nuggets. Children 6 months to 2 years old: Use the form of nuggets. If you forget a dose of Givet 5, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose as usual.
When using an overdose of Givet 5, you may have symptoms such as: Abdominal pain, headache, drowsiness, thirst, vomiting, hyperactivity. You need to go to the nearest medical facility for timely treatment.

A very common side effect of Givet 5 is an upper respiratory tract infection. Common side effects of Givet 5 include:
Diarrhea, nausea, vomiting. Increased serum ALT and AST levels. Fever, rash. Less common side effects of Givet 5 include:
Hypersensitivity reactions including anaphylaxis. Nightmares, sleepwalking, insomnia. Anxiety, agitation, depression, hyperactivity. Dizziness, drowsiness, paresthesia, convulsions. Epistaxis . Dry mouth, indigestion. Urticaria, itching, bruising. Joint pain, muscle pain. Weakness, irritability, fatigue, edema. Rare side effects of Givet 5 include:
Increased bleeding tendency. Heart beats fast. Memory loss. Angioedema. Very rare side effects of Givet 5 include:
Hallucinations, disorientation, suicidal behavior. Eosinophilic infiltration in the liver. Erythema variety. Hepatitis. If in the process of using Givet 5 there are any adverse effects, please inform your doctor to receive appropriate support.

Givet 5 can be used with other drugs in the prevention and treatment of chronic asthma and allergic rhinitis. At the recommended dose, Givet 5 does not significantly change the pharmacokinetics of drugs such as theophylline, prednisone, oral contraceptives, etc. Givet-5 is metabolized by CYP3A4, 2C8, 2C9 enzymes, so it is necessary Use caution when using with inducers of these enzyme systems such as phenobarbital, phenytoin, rifampicin (especially when used in children because of the risk of dangerous overdose). Gemfibrozil increases the AUC of Givet 5mg by 4.4 times, cautioning against the increased risk of side effects.

Notify the doctor immediately if the disease tends to get worse. Do not use Givet 5 to treat acute asthma. Givet 5 is not a substitute for other asthma medications. Do not take medications that make asthma worse, such as aspirin, NSAIDs. Givet 5 contains lactose, so it is contraindicated for people who do not have the enzyme to digest this sugar. Givet 5 medicine contains some excipients that can cause allergies such as polysorbate, quinoline yellow color, sunset yellow color. Excipients of castor oil in the medicine can cause diarrhea, abdominal pain.