Uses of Griacron

Griacron is made in the form of tablets with the main ingredient in each tablet is Gliclazide 80mg. So what is the drug Griacron, its use, how to use it and how to pay attention when using it?

The main ingredient of Griacron is Gliclazide, which is a sulfonylurea hypoglycemic drug, but it differs from related drugs by having an extra azabicyclo-octane ring.
Gliclazide has an effect on increasing insulin secretion mainly in phase 1, but it also increases insulin secretion to a lesser extent in phase 2. The amount of insulin secreted in both phases is reduced in type 2 diabetes.
Griacron is indicated in the following cases:
Non-insulin dependent diabetes. Griacron is contraindicated in the following cases:
Diabetes in children. Complicated diabetes mellitus in the stages of ketoacidosis and acidosis. Pregnant women. Patients with diabetes who have undergone surgery, after trauma or are suffering from an infection. Hypersensitivity to other drugs of the sulfonylurea group and related drugs. Diabetic patients are in a pre-coma or coma. Severe kidney or liver failure. Note when using Griacron in the following cases:
Some drugs of the Sulfonylurea group are distributed into breast milk. Therefore, Griacron should be avoided during breastfeeding. Hypoglycemia can occur while driving, if this happens you need to stop driving as soon as possible, quickly replenish sugar with candies, sugary drinks, ... and Leave the car seat, turn off the engine. Patients with impaired consciousness due to hypoglycemia or frequent hypoglycemia should not drive.

Griacron is used orally, with a 12 to 24 hour duration of action. Because the potency of Griacron is shorter than that of clopropamide or glibenclamide, it is more suitable for elderly patients who are prone to hypoglycaemia when taking long-acting sulfonylurea drugs.
Take a single dose of Griacron in the morning, swallow the tablet whole, do not chew, break or break the tablet.
Dosage of Griacron drug should be according to the doctor's instructions, the reference dose is as follows:
The starting dose is 30mg, once a day. If blood glucose is controlled, consider it as a maintenance dose. If blood glucose control is not achieved, it is necessary to gradually increase the dose to 60mg, 90mg, 120mg/day in increments, the dose increases need to be spaced at least once a month. May be used in combination with metformin or an α-glucosidase inhibitor (acarbose) or with insulin (close monitoring is required). Symptoms of an overdose of Griacron are hypoglycemia. Treat this condition by gastric lavage and correct hypoglycaemia with appropriate measures, continuously monitoring the patient's blood glucose until the effects of the drug have been ruled out.

During the use of Griacron, you may encounter some side effects of the drug, including:
Nausea, vomiting. Belching. Anorexia. Diarrhea. The mouth has a metallic taste. Increase appetite. Weight gain. Skin rash and pruritus, usually the form of a hypersensitive reaction and can progress to more serious disorders. Light sensitive. Red face. Mild hypoglycemia. Increase liver enzymes. Hepatitis . Cholestatic jaundice. Leukopenia. Decreased platelets. Aplastic anemia. Loss of granulocytes. Hemolytic anemia. Erythema variety. Stevens-Johnson syndrome. Inflammation of the skin. Red rash on the skin. During the use of Griacron, if you see any unusual symptoms, immediately notify your doctor or go to a medical facility for timely treatment.

Griacron should be used with caution with drugs known to alter diabetes status or enhance their effects. The hypoglycemic effect of Griacron may occur when co-administered with Phenylbutazone, Sulfonamides, Salicylates, Coumarin derivatives, MAOIs, β-adrenergic blocking agents, Tetracycline compounds, Chloramphenicol, Disopyramid, Clofibrat, Miconazole (oral form) and Cimetidine. Griacron may be reduced by corticosteroids, oral contraceptives, phenothiazine derivatives, thiazide diuretics, thyroid hormones and laxative abuse. Above is all information about Griacron drug, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Note, Griacron is a prescription drug, you need to use it as prescribed by your doctor, absolutely do not self-treat at home.