Uses of Maxcefu

What is Maxcefu drug? Maxcefu medicine has the main active ingredient is Cefuroxim Axetil with the strength of 500mg and other excipients in sufficient quantity. This is an antibiotic that is used in the treatment of diseases caused by bacterial, parasitic or fungal infections.
Maxcefu drug is prepared in the form of film-coated tablets, suitable for direct oral use. Packing is a box of 10 pills and each blister contains 8 tablets.
1.1. Pharmacodynamics of the active ingredient Cefuroxime Cefuroxime Axetil: oral form, dose expressed in terms of equivalent amounts of cefuroxime. Cefuroxime is a second generation cephalosporin antibiotic. 1.2. Cefuroxime pharmacokinetics After oral administration, the main active ingredient Cefuroxime axetil is rapidly absorbed from the gastrointestinal tract and hydrolyzed in the intestinal mucosa and blood to release Cefuroxime into the systemic circulation. The drug is best absorbed when taken with meals. The mean serum half-life is 1 to 1.5 hours. The degree of protein binding is shown to vary from 33 to 50% depending on the method used. Active substance Cefuroxime is not metabolized and is eliminated by glomerular filtration and tubular secretion. 1.3. Effect of active ingredient Cefuroxime Active ingredient Cefuroxime is a semi-synthetic broad-spectrum antibiotic, belonging to the Cephalosporin group, sodium salt injection, oral axetil ester. Cefuroxime axetil is a prodrug of the antibiotic cefuroxime, which has little antibacterial activity when it is not hydrolyzed to cefuroxime in the body after absorption. Cefuroxime has antibacterial activity due to inhibition of bacterial cell wall synthesis by binding to essential target proteins (penicillin-binding proteins). Cefuroxime resistance can be caused by bacteria secreting cephalosporinase enzymes, or by alteration of penicillin-binding proteins. Cefuroxime has a very specific and effective antibacterial activity against a wide range of common pathogens, including beta-lactamase/cephalosporinase-producing strains of both gram-negative and gram-positive bacteria. Cefuroxime is particularly stable to many beta-lactamase enzymes of gram-negative bacteria.

Maxcefu medicine is used in the treatment of specific diseases as follows:
Lower respiratory tract infections such as acute and chronic bronchitis, pneumonia. Upper respiratory tract infections: ear, nose and throat infections such as sinusitis, otitis media, tonsillitis or pharyngitis. Urogenital infections such as cystitis, pyelonephritis, urethritis, specific skin and soft tissue infections such as boils, pustules, impetigo. Gonorrhea; acute urethritis without complications from gonococcal and cervicitis.

3.1. How to use Maxcefu Drugs Maxcefu is made in the form of film-coated tablets, suitable for direct oral use.
3.2. Dosage of Maxcefu 3.2.1. Dosage for adults: Dosage for treatment of bronchitis and pneumonia is 500mg x 2 times/day. Dosage for most infections: 250mg twice daily. Dosage for treatment of urinary tract infections, the dose is 125mg x 2 times/day. Dosage for treatment of uncomplicated gonorrhea: a single dose of 1g 3.2.2. Dosage for children The usual dose is 125mg x 2 times/day or 10mg/kg x 2 times/day. Maximum dosage is 250mg/day. Children over 2 years old with otitis media should be given a dose of 250mg x 2 times/day or 15mg/kg x 2 times/day, up to a maximum of 500mg/day. Some notes:
Special caution is not required for patients with renal failure or on dialysis or the elderly when taking no more than the usual maximum dose of 1g/day. The usual course of treatment with this drug is 7 days. Film-coated tablets and oral suspension are not bioequivalent, so they cannot be substituted in terms of the mg/mg relationship. The above drug dosage is for reference only, patients need to take the drug as directed to improve the effectiveness of treatment and avoid unwanted side effects.
3.3. Overdose / missed dose In case of drug overdose: Most drugs only cause nausea, vomiting and diarrhea. However, overdose can also cause neuromuscular hyperexcitability and convulsions, especially in patients with renal failure. Treatment: it is necessary to immediately bring the person who overdosed on the drug to the nearest medical facility for timely and proper treatment. Doctors may prescribe protection of the patient's respiratory tract, ventilation support, and intravenous fluids. If the patient develops convulsions, stop taking the drug immediately; Anticonvulsant therapy may be used if clinically indicated by the treating physician. Hemodialysis can remove drugs from the blood, but most treatment is supportive or symptom-specific. In case of missed dose: Add the missed dose as soon as you remember it. However, if the interval between the next dose is too short, it is important to skip the missed dose and continue with the dosing schedule. You should be absolutely careful not to take a double dose to make up for a missed dose.

Undesirable effects of the drug Maxcefu may occur during use as follows:
Besides the therapeutic effects of the drug, during treatment with Maxcefu may also encounter some effects. unexpected. Most of the adverse effects caused by Maxcefu are mild and transient: gastrointestinal disturbances, diarrhea, nausea, vomiting, abdominal pain. Increased eosinophil count and transient elevation of liver enzymes. As with broad-spectrum antibiotics, a few (very rare) reports of pseudomembranous colitis and headache have also been reported. The above does not include all the unwanted effects and other side effects that may also occur during use. You need to pay attention to proactively notify the treating doctor for medical advice about adverse effects when using Maxcefu.

Interactions of the drug Maxcefu may occur during use as follows:
Decreased effect: Ranitidine with sodium bicarbonate reduces the bioavailability of drugs containing the active ingredient Cefuroxime axetil. You should take Maxcefu at least 2 hours after antacids or H2 blockers, as these can increase gastric pH. Increased effect: High doses of probenecid reduce renal clearance of active cefuroxime, resulting in higher and more prolonged plasma concentrations of cefuroxime. Increased toxicity: Aminoglycosides cause increased potential for nephrotoxicity. Maxcefu drug interactions may change its ability to work or increase the effects of unwanted effects. You need to take the initiative in telling your treating doctors or clinical pharmacists about the herbal products or health foods, prescription and over-the-counter medicines you are taking. used to minimize adverse drug interactions that may cause unwanted effects on the health of the user.
Interaction of Maxcefu with food and drink: When using this drug with foods or alcohol, beer, tobacco... because in foods and beverages containing other active ingredients Therefore, it can cause antagonism or synergistic effects with the drug. You need to actively read the instructions for using Maxcefu carefully or consult your treating doctor about how to use Maxcefu with foods, drinks containing alcohol or smoking.

6.1. Contraindications of the drug Maxcefu Do not use the drug Maxcefu for people with hypersensitivity or sensitivity to Cephalosporin antibiotics Contraindications of the drug Maxcefu are absolute contraindications, that is, in any case In any case, these contraindications cannot be flexible in the use of the drug. To ensure the effectiveness of treatment, it is best for the user of the drug to strictly follow the instructions of the treating doctor about the dose and how to use it. 6.2. Precautions of Maxcefu Before starting treatment with Maxcefu, it is necessary to carefully investigate the patient's history of allergy to Cephalosporin antibiotics, penicillins or other drugs. Because cross-sensitivity reactions (including anaphylaxis) have occurred among patients allergic to beta-lactam antibiotics, appropriate caution and readiness should be exercised to treat anaphylaxis when Use Maxcefu for patients who have previously been allergic to penicillin. However, with the antibiotic Cefuroxime, there is a low rate of cross-sensitivity to penicillin. Although the antibiotic Cefuroxime rarely causes changes in renal function, it is still advisable to monitor the kidneys during treatment with Cefuroxime or Maxcefu, especially for critically ill patients taking the maximum dose. Caution should be exercised when administering to patients or concomitantly with potent diuretics, because of the potential for adverse effects on renal function. Long-term use of Maxcefu may cause overgrowth of non-susceptible strains. In case of severe superinfection during treatment, Maxcefu should be discontinued. Currently, there have been reports of pseudomembranous colitis occurring with the use of broad-spectrum antibiotics, so it is important to diagnose this disease and treat with antibiotic metronidazole for patients with severe diarrhea due to the use of antibiotics. antibiotics. Extreme caution should be exercised when prescribing broad-spectrum antibiotics to people with gastrointestinal disease, especially colitis. Increased nephrotoxicity has been reported with concomitant use of Aminoglycoside and Cefuroxime antibiotics. Similar to other medicines, if you are pregnant or breastfeeding, you should consult your treating doctor or pharmacist before using Maxcefu. Effects of Maxcefu on the ability to drive and use machines: No significant effects. Store Maxcefu medicine in a dry place, at a temperature of 15 - 30 degrees Celsius in tightly closed packages, away from moisture and away from direct light. Besides, it is necessary to store Maxcefu medicine out of reach of children and family pets. Absolutely do not use Maxcefu when it has expired, is watery, distorted, or shows signs of being metamorphosed. Consult with environmental protection companies for how to dispose of drugs. Never throw away or flush the medicine down the toilet or plumbing. Maxcefu medicine has the main active ingredient is Cefuroxim Axetil with the strength of 500mg and other excipients in sufficient quantity. This is an antibiotic that is used in the treatment of diseases caused by bacterial, parasitic or fungal infections. When prescribed by a doctor, you need to carefully read the instructions for use of the drug, consult the treating doctor/clinical pharmacist before using the drug. Absolutely do not arbitrarily buy Maxcefu medicine to treat diseases at home, because there may be unwanted side effects to health.
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