Uses of Prazav

Prazav is formulated in the form of enteric coated capsules with the main ingredient in each tablet being Omeprazole 40mg. So, what is Prazav, how does it work and how to use it?

Prazav medicine has the main ingredient Omeprazole, this is a specific inhibitor that works by blocking the enzyme system of Hydrogen-potassium Adenosine Triphosphatase, also known as the proton pump H + K + ATPase of the gastric parietal cells.
Omeprazole acts at the end of the acid secretion process, a single dose of Omeprazole 20mg/day causes rapid inhibition of gastric secretion due to any stimulus. Omeprazole has no effect on acetylcholine or histamine receptors and has no significant pharmacokinetic effects other than on acid secretion. Omeprazole has a long-term, but reversible, gastric acid lowering effect.
After stopping the drug for 5 days, gastric secretion returned to normal, but there was no increase in acid secretion. Endoscopic examination showed that the healing rate of duodenal ulcers reached 65% after 2 weeks of treatment and up to 95% after 4 weeks.
Prazav is indicated in the following cases:
Gastroesophageal reflux disease (GERD); Gastrointestinal ulcers; Zollinger-Ellison syndrome. Prazav is contraindicated in the following cases:
People with hypersensitivity to Omeprazol, Esomeprazol; other Benzimidazole derivatives such as Pantoprazol, Lansoprazole, Rabeprazole or any ingredient of Prazav. Note when using Prazav:
Patients with liver dysfunction. Before starting treatment with Prazav, it is necessary to check the benignity of the ulcerative lesions. During treatment, you must not stop taking Prazav on your own, but must consult with your treating doctor before making a decision. Prazav should be used with caution in pregnant and lactating women.

Prazav is for oral use, should be swallowed whole, not crushed or chewed. The dosage of Prazav should be according to the doctor's prescription, the reference dose for specific cases is as follows:
Relieve symptoms of acid indigestion: Use a dose of 10 or 20mg/day for 2-4 weeks. Treatment of gastroesophageal reflux disease (GERD): The usual dose is 20mg x 1 time / day, used continuously for 4 weeks, an additional 4-8 weeks if not completely cured. In cases of persistent esophagitis, Prazav can be used at a dose of 40 mg/day. The maintenance dose of Prazav after healing of esophagitis is 20 mg once daily and 10 mg/day for acid reflux. Treatment of peptic ulcers: Use a single dose of 20mg/day or 40mg/day in severe cases. Continue treatment for 4 weeks for duodenal ulcers and 8 weeks for gastric ulcers. Maintenance dose is 10-20mg x 1 time/day. For eradication of Helicobacter pylori in peptic ulcers: Prazav can be combined with antibiotics at a dose of 20 mg twice daily for 2 weeks in dual therapy and for 1 week in triple therapy. Treatment of gastric ulcers caused by non-steroidal anti-inflammatory drugs: Use a dose of 20mg/day; This dose is also used for prophylaxis in patients with a history of gastrointestinal injury who require continued treatment with non-steroidal anti-inflammatory drugs. Zollinger-Ellison syndrome: Use a dose of 60mg x 1 time / day, adjust as necessary. The majority of patients are effectively controlled at doses ranging from 20 to 120 mg/day, but doses up to 120 mg 3 times/day can also be used. Doses of more than 80mg per day should be divided into 2 doses. Prevention of acid aspiration during general anesthesia: Use 40 mg the evening before surgery and an additional 40 mg 2 to 6 hours before surgery. No dose adjustment of Prazav is required in patients with impaired renal function. Patients with hepatic impairment: Use dose 10-20mg/day. There is no need to adjust the dose of Prazav in the elderly.

Common side effects of Prazav include:
Headache; Sleepy; Dizzy ; Nausea, vomiting; Stomachache; Diarrhea; Constipation; Distention . Rare side effects of Prazav include:
Insomnia; Confusion; Dizzy; Tired; Urticaria ; Itchy; A rash; Increased transaminases (reversible). Rare side effects of Prazav include:
Sweating; Peripheral edema; Hypersensitivity such as angioedema , fever and anaphylaxis; Leukopenia; Thrombocytopenia; Decrease in whole blood cells; Agranulocytosis; Reversible confusion; agitation; Depression ; Illusion; Hearing disorders; Large breasts in men; Gastritis; Candida infection ; Dry mouth; Hepatitis; Encephalopathy in people with liver failure; Bronchospasm; Joint pain, muscle pain; Interstitial nephritis. During the use of Prazav, if you see any unusual symptoms, you should immediately notify your doctor or go to a medical facility for timely treatment.

Prazav may interact with the following drugs:
Proton pump inhibitors (PPIs); Clopidogrel . In summary, Prazav is a prescription drug for the treatment of gastroesophageal reflux disease, peptic ulcers, and Zollinger-Ellison syndrome. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Sulfaprim exactly as directed by your doctor.