Uses of Savijoin 250 and 500

Savijoin 250 and 500 drugs have the main ingredient of Cephalexin antibiotic in the form of Cephalexin monohydrate with the respective concentrations of 250mg and 500mg. These two drugs are antibiotics that are used to treat diseases caused by parasites, bacteria, fungi, and viruses.
Savijoin 250 and 500 drugs are prepared in the form of film-coated tablets, suitable for direct oral use. Packing is a box of 10 blisters, each blister contains 10 tablets.
1.1. Pharmacodynamics of active ingredients Cephalexin Antibiotics Cephalexin is a bactericidal antibiotic with activity against a wide range of gram-positive and gram-negative bacteria.
Cephalexin antibiotic is stable to the action of penicillinase of Staphylococcus, thus resistant to strains of Staphylococcus aureus that are not sensitive to Penicilli (or ampicillin) due to the ability to produce penicillinase enzyme. The antibiotic Cephalexin is also active against most ampicillin-resistant E. coli.
1.2. Pharmacokinetics of the active substance Cephalexin Main active substance Cephalexine is almost completely absorbed, even in the presence of food and is not affected by gastrointestinal diseases, after partial gastrectomy, the hydrochloric acid deficiency, jaundice or diseases with diverticula (in the duodenum or jejunum). Cephalexin is excreted in high concentrations in the urine. The half-life is usually about 1 hour, but the duration is longer for infants. Active ingredient Cephalexin has a high level of safety. 1.3. Effect of active ingredient Cephalexin Active ingredient Cephalexin has a medium spectrum of activity, effective against gram-positive bacteria such as staphylococcus, streptococcus, pneumococcus (except methicillin-resistant streptococcus). The active ingredient Cephalexin is also effective against some gram-negative bacteria such as E.coli, Klebsiella pneumoniae, Proteus mirabilis and Shigella. There are specific drug-resistant strains such as: Enterococcus, methicillin-resistant Staphylococcus, indole-positive Proteus, Enterobacter, Pseudomonas aeruginosa, Bacteroides.

Savijoin 250 and 500 are prescription drugs used by doctors to treat infections caused by susceptible bacteria:
Treatment of respiratory tract infections: acute and chronic bronchitis, pneumonia , infectious bronchiectasis. Treatment of ear-nose-throat infections such as otitis media, sinusitis, tonsillitis or pharyngitis. Treatment of urinary tract infections: cystitis or prostatitis. Prophylactic treatment of recurrent urinary tract infections. Treatment of infections in obstetrics and gynecology Treatment of dental infections Treatment of specific skin and soft tissue infections such as boils, pyoderma and impetigo.

3.1. How to use Savijoin 250 and 500 Savijoin 250 and 500 are made in the form of film-coated tablets, suitable for direct oral use.
3.2. Dosage of Savijoin 250 For adult users: take 1-2 tablets/time, 3-4 times/day. For users who are children: 25mg - 60mg/kg/day, divided into 3-4 times. 3.3. How to handle an overdose of Savijoin 250 and 500 In case of drug overdose, the common unwanted effects are mainly nausea, vomiting and diarrhea, can cause neuromuscular hypersensitivity and seizures, especially for people with kidney failure.
Management of drug overdose Savijoin 250 and 500 should consider the possibility of overdose of different drugs, drug interactions and unusual pharmacokinetics of the patient:
No need to perform gastric lavage , unless cephalexin 5 to 10 times the usual therapeutic dose has been taken. Protect the patient's respiratory tract, perform ventilatory support and administer fluids. Give activated charcoal pills to users multiple times in place of or in addition to gastric lavage. Pay attention to protect the patient's respiratory tract while doing gastric lavage or using activated charcoal.

During treatment, a small number of people using Savijoin 250 and 500 may experience the following undesirable effects:
Common undesirable effects with the digestive system such as diarrhea, nausea and vomiting vomit. As with other broad-spectrum antibiotics, the antibiotic Cefalexine can induce symbiotic bacterial growth (can sometimes appear Candida albicans as vaginitis).
Uncommon side effects:
For blood: increased index, eosinophil count. For skin: rash, urticaria, skin rash. For liver: reversible increase in liver transaminases. Rare adverse effects:
Body as a whole: headache, dizziness, anaphylactic reactions, fatigue. Blood: decreased neutrophil count, decreased platelet count. For the digestive system: digestive disorders, abdominal pain, pseudomembranous colitis. For skin: Stevens Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, Quinke edema. For the liver: hepatitis, cholestatic jaundice. For the genitourinary system: itching in the genitals, vaginitis, reversible interstitial nephritis.

5.1. Contraindications of Savijoin 250 and 500 Active ingredients Cephalexin should not be used in patients with a history of allergy to cephalosporin antibiotics. Do not use drugs containing the active ingredient Cephalosporins, specifically Savijoin 250 and 500, in patients with a history of penicillin-induced anaphylaxis or other serious IgE immune globulin-mediated reactions. 5.2. Precautions of Savijoin 250 and 500 Using Savijoin 250 and 500 for a long period of time can cause superinfection with non-susceptible bacteria. For people with renal failure: reduce the dose and closely monitor the patient. The doctor will order to check the function of hematopoietic, kidney and liver in long-term treatment. Use with caution if you have a history of diseases related to the stomach - intestines, especially inflammatory bowel disease. The safety of the antibiotic cefalexin during pregnancy has not been established. 5.3. Recommendations when using the drug You should keep this medicine out of the reach of children and pets in your family. Read the instructions for use carefully before taking this medicine. Use in pregnancy: Experimental studies and clinical experience have not revealed any evidence of toxicity to the fetus and teratogenicity. However, the drug should be used during pregnancy only when absolutely necessary after being weighed by the treating doctor about the benefit to the mother and the possible risk to the baby. Lactation: Concentrations of Savijoin 250 and 500 in breast milk are very low. Even so, you should still consider temporarily stopping breastfeeding while you are being treated with this medicine. Effects of drugs on driving vehicles and operating machines: Currently, there are no specific studies. Above is all information about Savijoin 250 and 500 drugs, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Savijoin 250 and 500 drugs to treat diseases at home, because there may be unwanted side effects on health.
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