Uses of Savispirono plus


Savispirono plus is often recommended by doctors to treat cases of chronic congestive heart failure, edema, essential hypertension,... Before and during treatment with Savispirono. , patients need to make sure to follow the doctor's instructions about the dose to get the best results.

1. What is Savispirono?


Savispirono belongs to the group of diuretics that are only allowed to be used when prescribed by a doctor, often used in cases of chronic congestive heart failure, essential hypertension, edema,...
Savispirono is used Prepared in the form of film-coated tablets, packed in boxes of 2 blisters x 10 tablets. In each Savispirono plus tablet will include 2 main active ingredients: Spironolacton (content 50mg), Furosemide (20mg content) and other excipients just enough.

2. Savispirono plus: Uses, indications and contraindications

2.1 Uses of Savispirono plus Each active ingredient in Savispirono plus will take on different tasks and roles, specifically:
Active ingredient Spironolaton: Has the effect of inhibiting sodium reabsorption in the distal tubule based on a mechanism inhibiting competition with Aldosterone, thereby increasing sodium and water excretion, providing antihypertensive and diuretic effects. Active ingredient Furosemide: Has a rapid and powerful diuretic effect by inhibiting the Na+/K+/2Cl- co-transport system, and at the same time blocking the reabsorption of K+, Na+, and Cl-. The combination of these two active ingredients in the same formula helps to provide complementary antihypertensive effects to each other.
2.2 Indications to use Savispirono plus Savispirono plus is usually prescribed for the following conditions:
Chronic congestive heart failure. Cirrhosis is accompanied by ascites (accumulation of fluid in the abdominal cavity). Essential hypertension. Aldosterone hypersecretion. Prevents edema caused by secondary hyperaldosteronism. 2.3 Contraindication to the use of Savispirono plus Do not use Savispirono plus for the following subjects without a prescription from a specialist:
People who are hypersensitive or allergic to Sulfonamide derivatives or any other ingredients other in the drug. Contraindicated in patients with acute renal failure, severe renal impairment (creatinine clearance < 30ml/min) or anuria patients. Do not use Savispirono plus for people with Addison's disease or experiencing hyperkalemia. Do not use Savispirono plus for people with hepatic pre-coma and coma.

3. Dosage and how to use Savispirono plus

3.1 Dosage of Savispirono plus The following is the recommended dose of Savispirono by the doctor:
Adults: Take 1 to 4 tablets a day depending on the level of response. For previously stabilized patients, a higher dose of Savispirono may be considered. Children: Savispirono plus is not recommended for this population. Elderly: The dose may be adjusted according to the doctor's prescription in case of need. 3.2 Instructions for proper use of Savispirono plus Savispirono plus is made in the form of tablets, so patients need to take it orally. When taking the drug, swallow the tablet whole with a sufficient amount of water. The drug can be used at any time of the day without affecting its effectiveness. When taking an overdose of Savispirono plus, patients may experience symptoms such as shortness of breath, anxiety, muscle weakness, confusion, cramps, low blood pressure, rapid pulse, headache, loss of appetite or thirst. . In this case, the patient needs to stop taking the drug and immediately go to the medical center for support.

4. Possible side effects when taking Savispirono plus


During the use of Savispirono plus, patients may experience some of the following side effects:
Common reactions: Somnolence, impotence, headache, fatigue, menstrual disorders, heavy milk flow, gynecomastia in men, postmenopausal bleeding, increased prolactin, nausea, diarrhea, orthostatic hypotension, hypovolaemia, hyponatremia/kalemia, hypochloremic alkalosis, hypocalcemia ,... Uncommon reactions: rash, erythema, hyperkalemia, hyponatremia, muscle spasms, cramps, urticaria, paresthesia, increased serum creatinine, gastrointestinal disturbances, nausea, vomiting. When noticing any side effects occurring after taking Savispirono plus, patients need to stop taking the drug and notify the doctor immediately for timely treatment.

5. Things to keep in mind when using Savispirono plus

5.1 What precautions should be taken while using Savispirono plus? The following patients need to be cautious during treatment with Savispirono plus:
People with diabetes or an enlarged prostate. People with electrolyte deficiency due to diarrhea or diuresis. People with reduced blood flow and low blood pressure. People with impaired kidney function. People with dysuria, prostate enlargement or acute urinary retention. People who are taking other diuretics. Pregnant women need to be cautious when taking the drug because Spironolactone can cross the placental barrier and cause feminization of the fetus, while Furosemide can cause defects in the fetus. Therefore, this subject should only use the drug when prescribed by a doctor. Savispirono plus may be excreted in breast milk and affect nursing infants, so women who are breastfeeding should weigh the risks and benefits before taking the drug. Savispirono plus may cause side effects such as drowsiness or fatigue, affecting the ability to drive and use machines. In addition, during the use of Savispirono plus, patients also need to be careful about possible side effects such as metabolic acidosis caused by hyperchloremia accompanied by hyperkalemia (for people with cirrhosis). decompensated liver but normal renal function). In addition, patients should also be aware that the use of Savispirono plus may change blood test parameters.
5.2 Interaction of Savispirono plus with other drugs Savispirono plus may interact when used with the following drugs:
Corticosteroids. Spironolactone drug. Non-steroidal anti-inflammatory drugs. Indomethacin drug. ACE Inhibitors 1. Potassium salts. Derivatives Indandion, Coumarin and Heparin. Lithium drug. Cardiac Glycosides. Cephaloridine drug. Aminoglycoside drugs. Diabetes medication. Cisplatin drug. Non-depolarizing muscle relaxants. Antihypertensive drugs. Sucralfate drug. Hopefully, the important information about the drug Savispirono plus will help the use and treatment achieve good results and minimize the side effects to the patient's health.

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