Uses of Synprazo

Synpraz medicine is made in the form of capsules, with the main ingredient being Lansoprazole. The drug is used in the treatment of certain diseases of the stomach - duodenum.

1 Synpraz tablet has the main ingredient Lansoprazole (enteric coated granules 8.5%) 30mg content and other excipients. Lansoprazole is a benzimidazole derivative, a strong acid secretion inhibitor, inhibiting the activity of H +, K + ATPase enzymes in the parietal cells of the gastric mucosa, playing an important role as a proton pump. Lansoprazole inhibits gastric acid secretion both basal and stimulated (by any agent). The degree of inhibition of acid secretion by the drug depends on the dose and duration of treatment.
Clinically, the drug Lansoprazole has the ability to heal quickly and effectively for gastric and duodenal ulcers (the healing rate - healing of ulcers can reach 96% after 8 weeks of treatment). In addition, the drug is also effective in the treatment of reflux esophagitis and Zollinger - Ellison syndrome. In particular, the drug has little effect on gastric juice volume, gastric endothelium, pepsin secretion and gastric contractility.
Indications for using Synpraz:
Treatment of gastric ulcer, duodenal ulcer; Treatment of reflux esophagitis; Treatment of Zollinger-Ellison syndrome. Contraindications to using Synpraz:
People with hypersensitivity to the active ingredients or excipients of the drug; Patients with malignant peptic ulcer.

Usage: Orally. Synpraz should be taken in the morning before meals.
Dosage: Adults take 1 capsule (30mg)/time/day. Specific dosage for each disease condition is as follows:
Duodenal ulcer: Use dose 30mg/time/day for 4 weeks; Stomach ulcer: Use 30mg/time/day for 8 weeks; Reflux esophagitis: 30mg/time/day for 4-8 weeks; Zollinger - Ellison syndrome: Dosage is adjusted according to the patient's symptoms (as prescribed by the doctor). Overdose, missed dose: Consult your doctor for appropriate advice.

When using Synpraz, patients may experience some side effects such as:
Hypersensitivity: Sometimes patients may experience itchy skin or a rash. In this case, the patient should stop taking the drug; Liver: There may be an increase in SGPT, SGOT, Phosphatase-alkali, LDH or G-GTP,... so the patient's liver function should be monitored. If abnormal signs appear, the drug should be discontinued; Blood: Leukopenia , eosinophilia, anemia, thrombocytopenia; Digestive: Constipation, dry mouth, diarrhea, abdominal distension; Psychiatric: Drowsiness, headache, dizziness, insomnia; Other side effects: Fever, increased uric acid, increased total cholesterol. When experiencing side effects of Synpraz, patients should promptly notify their doctor to receive appropriate advice and advice on the best response.

Some notes patients should remember before and while taking Synpraz:
During treatment, it is necessary to carefully monitor the condition of the disease. Lansoprazole should not be used in maintenance therapy if there is insufficient experience with long-term use; Use caution when using Lansoprazole in patients with a history of drug sensitivity, patients with liver dysfunction; To date, the safety of Lansoprazole in children has not been established. Therefore, the drug should not be used for this group of people; In the elderly, acid secretion and other physiological functions are impaired. Therefore, Lansoprazole should be used in this population with caution; In studies in rats, concentrations of lansoprazole in embryonic serum were higher than in maternal rats. In rabbits (30mg/kg oral dose) increased embryonic mortality. Therefore, Lansoprazole should not be used in women who are pregnant or suspected of being pregnant, unless absolutely necessary and approved by a doctor; It has been reported in animal studies that Lansoprazole is excreted in human milk. Therefore, the use of Lansoprazole should be avoided in nursing mothers, if necessary, breastfeeding should be discontinued; Because Synpraz can cause dizziness, headache, drowsiness, ... should be used with caution when using this drug in drivers, operating machinery.

Some drug interactions of Synpraz include:
Lansoprazole is metabolized by the cytochrome P450 enzyme system, so the drug has the ability to interact with other drugs that are metabolised by this same enzyme system. Therefore, Lansoprazole should not be used concomitantly with other drugs that are metabolised by cytochrome P450; No clinically important effects on the levels of theophylline, prednisolone, diazepam, phenytoin or warfarin have been observed when co-administered with lansoprazole; Lansoprazole reduces the effect of itraconazole, ketoconazole and other drugs whose absorption requires an acidic environment in the stomach; Sucralfate slows and reduces the absorption of Lansoprazole by about 30%. To avoid the risk of drug interactions, before using Synpraz, patients need to inform their doctors about the drugs they are taking and their medical history. In addition, patients should not arbitrarily start, stop or change the dose of any medication without the consent of the doctor. Proper adherence to treatment indications will ensure effective treatment and limit the risk of dangerous complications.