Uses of Tazeurin

What does Tazeurin do? Tazeurin belongs to the group of psychotropic drugs with the main ingredient mirtazapine 30mg, effective in the treatment of depressive episodes. Among them, mirtazapine is a central presynaptic A2 antagonist that increases central noradrenalin and serotonin mediated neurotransmission. Serotonin-mediated enhancement of neurotransmission is only through specific 5-HT1 receptors. Because the 5-HT3 and 5-HT2 receptors are blocked by mirtazapine, two enantiomers of mirtazapine that both participate in antidepressant activity, the S(+) enantiomer blocks the 5-receptor. HT2 and a2. The 5-HT3 receptor is blocked by the R(-) enantiomer. Mirtazapine has histamine H1 antagonist activity related to its sedative properties, and is generally very well tolerated. Tazeurin has almost no anticholinergic activity and at therapeutic doses has almost no effect on the cardiovascular system.
Mirtazapine is rapidly and well absorbed, reaching peak plasma concentrations after about 2 hours. Approximately 85% of mirtazapine is bound to plasma proteins. The active substance mirtazapine is extensively metabolised and is excreted in the feces and urine within a few days. The major biological transformations are demethylation and oxidation, followed by conjugation. The demethylated metabolite is pharmacologically active and has the same pharmacokinetic properties as the parent compound. The half-life of Tazeurin ranges from 20-40 hours. Sometimes the half-life is longer which can be up to 65 hours, in younger men usually has a shorter half-life. Concentrations of the drug reach steady state after 3-4 days, then no further accumulation. The clearance of mirtazapine may be decreased by hepatic or renal impairment.

Tazeurin is made in the form of film-coated tablets with the following dosage:
For adults, the recommended therapeutic dose is 15mg/day. It is usually necessary to increase the dose to achieve optimal clinical responses. The daily therapeutic dose ranges from 15-45mg. For the elderly, the dosage is similar to that of adults. In elderly patients, dose escalation should be closely monitored for a safe and satisfactory response. For children: Currently, the effectiveness and safety of Tazeurin in children has not been established, so treatment in children is not recommended. . Tazeurin has a half-life of 20-40 hours, making it suitable for once-daily dosing. Patients should take the drug in the evening before going to bed, or divide the dose to take 2 equal times a day.

Some unwanted effects that may occur while taking Tazeurin include:
Increased appetite and may lead to weight gain Drowsiness: It usually occurs during the first few weeks of treatment. It is possible to reduce the dose that usually does not reduce the sedative effect but may reduce the antidepressant efficacy. Postural hypotension Manic episodes Convulsions Tremor Muscle tremors Edema and weight gain Acute bone marrow suppression such as agranulocytosis, eosinophilia, agranulocytosis, aplastic anemia,... Increased serum transaminase activity Rash Serious allergic reaction such as difficulty breathing, edema, swelling of the face, nose, throat, rash, etc. medical attention for prompt medical intervention.

In the course of treatment, in order to use the drug to achieve the highest efficiency and minimize unwanted effects, the patient needs to pay attention to a number of issues such as:
You need to inform the doctor about the money. History of hypersensitivity to Tazeurin or any other allergy. Tazeurin may contain ingredients that don't work and could cause an allergic reaction or other serious problems. List any medications you are taking for your doctor to know including prescription and over-the-counter medicines, herbs or preservatives, dietary supplements, and foods or dyes. Tazeurin should be used with caution in patients with epilepsy, organic brain syndrome, kidney failure, liver failure, cardiovascular disease, low blood pressure, urinary disorders such as prostate enlargement, glaucoma. pressure and acute narrow-angle glaucoma, diabetes,... Should stop the drug if symptoms such as fever, sore throat, jaundice, stomatitis or other signs of infection appear. For pregnant and lactating women, Tazeurin should only be used when absolutely necessary, because until now, the safety of Tazeurin in pregnant and lactating women has not been proven. Before the end of the course of treatment, the patient should not arbitrarily skip the dose or stop the drug, even though the symptoms may have improved. Take the dose you forgot to take as soon as possible. In addition, the time to add the dose should not be too close to the next dose and the missed dose can be skipped to continue taking the medicine as originally scheduled.

Drug interactions have the potential to change the way a drug works or increase the risk of serious unwanted effects. Certain medicines should not be used at or around the time of treatment with Tazeurin. However, in some other cases, 2 different drugs can be used together even if they can interact. In this particular case, doctors need to change the dosage of the drug or take other prevention methods. Therefore, the patient should inform the doctor about the drugs and supplements you are taking.
Some drugs that can interact with Tazeurin include:
MAO inhibitors: Tazeurin and Mao inhibitors should not be used concurrently within 2 weeks of stopping treatment. Benzodiazepines: Tazeurin can enhance the sedative effect, so caution should be taken when using sedatives with Tazeurin. Tazeurin may enhance the CNS depressant effects of alcohol. Therefore, patients should abstain from alcohol during treatment with Tazeurin.

Tazeurin drugs are preserved at medical facilities under the following conditions:
Stored at room temperature; Avoid light; Avoid humid places; Do not store Tazeurin in a humid place or in the freezer. With each drug Tazeurin will have different ways of preservation, so please read the instructions for use and storage carefully before using. Also, keep Tazeurin out of the reach of children and family pets. If a dose of medicine has expired or is damaged and cannot be used anymore, it must be disposed of according to the correct procedure. Do not arbitrarily dispose of Tazeurin into an environment such as a water pipe or toilet unless requested to do so. Consult with the environmental company or pharmacist on how to safely dispose of Tazeurin to help better protect the environment.
In summary, Tazeurin is a psychotropic drug that is effective in the treatment of depressive episodes. However, being in the process of using the drug will not be able to avoid unwanted side effects occurring. Therefore, if you feel that your body shows unusual signs, you need to immediately go to a medical facility for timely treatment.
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