Uses of Zalilova

The antibacterial effect of the active ingredient Cefpodoxime in Zalilova is through the inhibition of bacterial cell wall synthesis by acylation of membrane-bound transpeptidase enzymes, which prevents cross-linking of peptidoglycan chains essential for the strength and strength of the bacterial cell wall. Cefpodoxime is active against both gram-negative and gram-positive bacteria.
Zalilova is indicated for use in the following cases:
Treatment of upper respiratory tract infections including: sinusitis, acute otitis media, pharyngitis, tonsillitis. Urinary tract infections without complications. Treatment of community-acquired acute pneumonia. Treatment of acute gonococcal infection without complications. Treatment of infections of the skin, skin structures and soft tissues. Zalilova is not contraindicated in patients with a history of hypersensitivity to Cefpodoxime, or to any of the excipients contained in the drug.

2.1. How to take Zalilova The drug Zalilova is prepared in the form of hard capsules, to be taken orally, the drug should be taken with food to achieve the maximum effect in treatment.
2.2. Dosage of Zalilova In adults:
Treatment of upper respiratory tract infections, including pharyngitis and tonsillitis: 100 mg/time, twice daily, for 10 days. Treatment of community-acquired acute pneumonia: 200 mg/time, twice daily for 14 days. Treatment of urinary tract infections without complications: 100 mg/time, twice a day, for 7 days. Treatment of skin and skin structure infections: 400 mg/time, twice daily, for 7-14 days. In children:
Treatment of acute otitis media: 10 mg/kg body weight/day (maximum dose of 400 mg/day, divided into 2 times), for 10 days. Treatment of tonsillitis and pharyngitis: dose 10 mg/kg body weight/day (maximum use 200 mg/day, divided into 2 times), for 10 days. In patients with renal impairment with creatinine clearance < 30 ml/min, the dosing interval should be increased every 24 hours. No dose adjustment is required in patients with cirrhosis.
Patients need to strictly follow the doctor's dosage instructions, do not arbitrarily calculate, apply or change the dose without consulting or agreeing with the doctor.

During treatment with Zalilova, besides the therapeutic effects of the drug, patients may experience the following undesirable effects: Nausea, vomiting, diarrhea, abdominal pain, headache, inflammation colon ... Rarely hypersensitivity reactions, pruritus, rash, thrombocytosis, dizziness, leukopenia, thrombocytopenia or eosinophilia have occurred.
The side effects are usually only mild and transient, disappear when the patient stops using Zalilova, however, the patient should be advised that if they experience any abnormal signs, they should immediately notify the doctor to are supported and handled efficiently and in a timely manner.

When there are indications for the co-administration of Zalilova with antacids or H2 inhibitors, plasma concentrations of the active ingredient Cefpodoxime proxetil have been reduced by about 30%. Close monitoring of the patient's renal function is recommended when Zalilova is administered with drugs known to have nephrotoxicity. When Probenecid is co-administered with Zalilova, there is an increase in the plasma concentration of Zalilova. Results of test values ​​changed: Zalilova made the direct Coomb test positive.

Attention and precaution: for patients who experience diarrhea after using Zalilova, it is necessary to think of pseudomembranous colitis. In patients who have had an anaphylactic response to penicillin, Zalilova should be used with caution. It is best not to use Zalilova for pregnant women and lactating mothers, only use it when absolutely necessary.

Store Zalilova medicine in a dry, cool place, the appropriate temperature is below 25 degrees Celsius, avoid direct exposure to sunlight or high temperature, these agents can cause changes in the activity. substance in the drug. Keep away from children's play areas to avoid misuse of drugs.
The shelf life of Zalilova is 30 months from the date of manufacture, do not use the drug when it has expired or has sensory changes such as color, watery, moldy.