Varubi: Uses, indications and precautions when using

Varubi is indicated for use in combination with other antiemetics for the prevention of late-phase nausea and vomiting in adults during cancer treatment.

Varubi (active ingredient Rolapitant) is used with other medicines to prevent delayed-phase nausea and vomiting caused by the effects of cancer drugs (chemotherapy). Rolapitant's mechanism of action is based on blocking one of the body's natural agents (substance P/neurokinin 1) that causes vomiting.

Carefully read the instructions for use of Varubi given by the doctor or pharmacist before the patient starts taking it. If you have any questions about your medicine, ask your doctor or pharmacist for answers.
Varubi is a medication to be taken by mouth, with or without meals as directed by your doctor, usually 2 hours before chemotherapy. Do not take this medicine more than once every 2 weeks.
Inform your doctor if vomiting persists or gets worse after taking Rolapitant .

During the use of Varubi, patients may experience stomach pain or mouth ulcers. If either of these effects persist or get worse, talk to your doctor right away to find a solution.
Before prescribing medicine, doctors always weigh the benefits and effectiveness of Varubi medicine more than the risk of side effects. However, some cases when using Varubi can still occur unwanted effects. Therefore, when unusual signs appear, especially when a severe allergic reaction occurs with accompanying symptoms such as difficulty breathing; severe dizziness; rash; itching or swelling of the face, throat, tongue, etc., the patient should immediately notify the medical staff for immediate intervention.
The article does not cover the full list of possible side effects of the active ingredient Rolapitant. If you notice other effects of Rolapitant not listed above, please contact your doctor or pharmacist for further instructions.

Before taking Varubi, tell your doctor if you are allergic to the active ingredient Rolapitant or any other allergies if any. Varubi preparations contain inactive ingredients, which may cause allergic reactions or other problems.
Before antiemetic with Varubi, patients need to talk to their doctor or pharmacist about their medical history.
Before surgery, tell your doctor or dentist that you are or have taken Varubi as well as all other products you use.
During pregnancy, Varubi should only be used when clearly needed and after discussing the risks and benefits with your doctor.
Consult your doctor before you breastfeed, as it is not known whether Rolapitant passes into breast milk.

Varubi drug interactions can change the effectiveness of the medicine or increase the risk of serious side effects. Tell your doctor about all the products you are using, including prescription drugs, over-the-counter medicines, and herbal products. Do not stop or change the dose of Varubi without your doctor's approval.
Varubi can slow the elimination of other drugs from your body, which affects their blood levels and leads to unwanted effects. This effect may last 4 weeks or longer after taking Varubi . Drugs affected by this mechanism include dextromethorphan, pimozide, thioridazine, and others.
Conversely, other drugs may also affect the elimination of rolapitant from the body and its ability to work. Drugs that cause this type of interaction include: Antibiotics of the rifamycin group (such as rifampin, rifabutin ) and some other drugs.

If you overdose on the drug Varubi and have serious symptoms such as fainting, difficulty breathing, contact your doctor or medical center immediately for professional help, avoid risks. unworthy.
An important issue when taking Varubi is to make sure you take it as scheduled, if you miss a dose, ask your doctor or pharmacist for a new dosing schedule, do not double your dose.
Store the medicine at room temperature, away from sunlight and moisture. Do not leave the medicine near children and pets. When the medicine is no longer usable or has expired, dispose of it properly.
Knowing the information about the drug Varubi before use always brings positive effects as well as reduces risks for patients. If you have any questions, you can send them to Vinmec International General Hospital to receive in-depth advice from a team of doctors and pharmacists with many years of experience.

Reference source: webmd.com