What are the uses of Tadalafil 20mg?

Erectile dysfunction is the inability to achieve or maintain an erection of the penis sufficient to perform satisfying sexual intercourse. Tadalafil is a prescription medication used to treat erectile dysfunction in adult men. So what does tadalafil 20mg do?

Tadalafil 20 mg has the active ingredient Tadalafil. It is indicated for the treatment of erectile dysfunction and the treatment of the signs and symptoms of benign prostatic hyperplasia in adult men.

Tadalafil is a selective, reversible inhibitor of cyclic guanosine monophosphate (cGMP) specifically phosphodiesterase type 5 (PDE5). When sexual stimulation leads to local release of nitric oxygen, inhibition of PDE5 by tadalafil increases cGMP concentrations in the corpus cavernosum. The result is smooth muscle relaxation and increased blood flow to the penile tissues, which in turn causes an erection. In the absence of sexual stimulation, tadalafil has no effect. Tadalafil 20 mg Stada is indicated for the treatment of erectile dysfunction in adult men. The drug only works when there is sexual stimulation.

How to use: Take the drug by mouth and independent of meals.
Dosage
Adults: The usual dose is 10 mg, at least 30 minutes before sexual intercourse. The daily dose may be increased to 20 mg or reduced to 5 mg as needed. The effect of the drug can last up to 36 hours after taking it. The maximum recommended dose is once a day and should not be used continuously every day because there are insufficient data on the safety of the drug in long-term use. Elderly patients: No dose adjustment is required. Patients with hepatic impairment: In patients with mild to moderate hepatic impairment, the maximum dose should not exceed 10 mg once daily. Tadalafil should not be used in patients with severe hepatic impairment. Patients with renal impairment: In patients with moderate renal impairment (creatinine clearance 31 - 50 ml/min), a dose of 5 mg should be initiated no more than once daily, up to a maximum dose not exceeding 10 mg once every 48 hours. . In patients with severe renal impairment (creatinine clearance less than 30 ml/min) including patients on hemodialysis, the maximum dose should not exceed 5 mg once daily. Patients stabilized on an alpha-blocker regimen: Tadalafil should be started at an initial dose of 5 mg. Patients taking strong inhibitors of cytochrome P450 isoenzyme CYP3A4: Tadalafil should not be taken more than 10 mg once every 72 hours. Children: The use of tadalafil in people under 18 years of age has not been evaluated, and tadalafil should not be given to children or infants. Note: The above dosage is for reference only. The specific dose depends on the condition and the progression of the disease. To get the right dose, you need to consult your doctor or healthcare professional.

When using Tadalafil 20 mg Stada, you may experience unwanted effects (ADRs) such as:
Common, ADR > 1/100
Nervous system: Headache. Cardiovascular: Flushing. Respiratory: Nasal congestion. Digestion: Indigestion, gastroesophageal reflux. Musculoskeletal: Back pain, muscle pain, limb pain. Uncommon, 1/1000 < ADR < 1/100
Immune system: Hypersensitivity reactions. Nervous system: Dizziness. Eyes: Blurred vision, eye pain. Ears: Tinnitus. Cardiovascular: Tachycardia, palpitations, hypotension, increased blood pressure. Respiratory: Shortness of breath, nosebleed. Gastrointestinal: Abdominal pain. Skin and subcutaneous tissue: Rash, increased sweating. Kidney and urinary tract: Hematuria. Reproductive system: Penile bleeding, bloody semen. General: Chest pain. Rarely, ADR < 1/1000
Visual disturbances (eg, blurred vision, change in color vision, conjunctivitis, eye pain, increased lacrimation, periorbital edema). When experiencing side effects of the drug, it is necessary to stop using it and notify the doctor or go to the nearest medical facility for timely treatment.

Tadalafil 20 mg 2X10 Stada is contraindicated in the following cases:
Hypersensitivity to tadalafil or any of its ingredients. Patients taking in combination with nitrates or organic nitrites, continuously and/or intermittently.

Patients with benign prostatic hyperplasia should be screened to exclude the possibility of prostate cancer and carefully evaluated for cardiovascular status before initiating treatment with tadalafil. Cardiovascular effects: Sexual activity is associated with cardiovascular risk. Therefore, the patient's cardiovascular status should be assessed prior to initiating treatment with tadalafil. Serious adverse events associated with tadalafil have been reported including myocardial infarction, sudden cardiac arrest, stroke, chest pain, palpitations and tachycardia. Erectile dysfunction should not be treated with tadalafil in patients who have been advised not to be sexually active because of a cardiovascular condition. Of particular concern is the risk of hypotension or vasodilatation in patients with left ventricular obstruction (aortic stenosis, idiopathic hypertrophic subaortic stenosis) or severely impaired autonomic control. pressure. Effects on vision: Tadalafil should not be used in patients with hereditary degenerative retinal disorders, including retinitis pigmentosa. Urogenital effects: The drug should be used with caution in patients with anatomical deformities of the penis (penile flexion, cavernosal fibrosis, Peyronie's disease) and conditions that predispose to penile pain (penile disease) sickle cell anemia, multiple myeloma, leukemia). Tadalafil should not be co-administered with other drugs for the treatment of erectile dysfunction because the safety and efficacy of these combinations have not been studied. The use of tadalafil in people under 18 years of age has not been evaluated. Therefore, do not give tadalafil to children or infants. Tadalafil Stada 20 mg contains lactose. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine. Tadalafil is not indicated for women. No studies on the effects on the ability to drive and use machines have been reported. Although the incidence of dizziness was similar between placebo and tadalafil in clinical trials, caution should be exercised if patients use tadalafil before driving or operating machinery. Tadalafil 20 mg is indicated for the treatment of erectile dysfunction and the treatment of the signs and symptoms of benign prostatic hyperplasia in adult men. To ensure the effectiveness of treatment, patients should take medicine according to prescription or consult a doctor, pharmacist for advice.
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