What is Hagizine 5mg?

Hagizin 5mg is used in cases of migraine or prevention of migraine, dizziness, vestibular disorders, ... thanks to its ability to inhibit calcium channels, antihistamine H1. Let's learn about drugs and how to use them effectively and safely through the article below.

Hagizin 5mg is a drug with the main ingredient is Flunarizine in the form of flunarizine dihydrochloride 5mg, the drug is made in the form of capsules.
Flunarizine is an antihistamine (H1) drug, it is a difluorine derivative of piperazine, structurally similar to Cinarizin. Therefore, flunarizine has similar pharmacological properties to Cinnarizine, but has a longer plasma half-life, so it can be treated with a once-daily regimen.
Flunarizine's mechanism of action is based on selective antagonism of the transmembrane calcium transporter in vascular smooth muscle cells, red blood cells, and brain cells. Since then, flunarizine helps inhibit the influx of calcium into the cell in cases where too much calcium enters the cell and causes cell damage due to calcium overload. Flunarizine also inhibits smooth muscle contraction due to extracellular calcium entry and most of the antihistamines (H1) as well as flunarizine have sedative effects.
The drug is used to prevent migraine, dizziness and vestibular disorders. Flunarizine is also used in cerebrovascular and peripheral circulatory disorders.

Hagizin medicine 5mg has anti-histamine, sedative and calcium channel blocker effects, so it is indicated for use in the following cases:
Prophylactic treatment of migraine or when some other treatment measures are not effective. Treatment of symptoms such as dizziness, dizziness, tinnitus, ... caused by vestibular disorders. Arousal disorders, memory loss, decreased concentration and sleep disturbances. The drug should not be used in the following cases:
Hypersensitivity to Flunarizine or any other excipients of the drug. Have had symptoms of Parkinson's disease since before starting treatment. History of extrapyramidal symptoms such as chorea, ring dance, myoclonic tremor,... Currently suffering from depression or a history of recurrent depressive syndrome.

Usage: The drug is taken orally, due to the long duration of action, it only needs to be used once a day. It is recommended to take it in the evening, as it also has a sedative effect.
Dosage:
For adults over 65 years old: Take 1 tablet once, once a day Adults (under 65 years old) and for children weighing 20 - 40kg: Take 2 tablets 1 time, once a day. Children under 20kg: Take 1 tablet each time and the interval between 2 doses is 2 days. In cases of migraine prophylaxis. If the patient responds well to the drug and requires maintenance therapy, the dose should be reduced by: Take 5 consecutive days with the above dose and take a break of 2 days per week. Treatment should not exceed 6 months and should be restarted only if relapse occurs. For patients with liver failure: It is necessary to adjust the lowest dose, should take 1 tablet per day. Because the drug is metabolized by the liver.

When using the drug, you should note a few things:
When taking the drug, you should tell your doctor about your medical condition and history of allergies, especially allergies to the ingredients of the drug. When taking the drug, patients may appear some side effects such as: Drowsiness, weight gain, nausea, dry mouth, feeling anxious. Rarely, side effects such as rash, myalgia, extrapyramidal symptoms such as chorea, rigidity, restless limbs, dyskinesia, tremor, ... When you see these side effects occur you You should consult your doctor for complete advice. If there is no improvement after about 8 weeks of treatment, the patient is considered unresponsive to the drug and should be considered for discontinuation of the drug. Do not use the drug for more than 6 months. When using the drug, if symptoms appear: depression, extrapyramidal disorders, increased fatigue, treatment should be stopped and re-examination for appropriate treatment measures. Do not use the drug in excess of the recommended dose and should be regularly and periodically monitored, especially during maintenance therapy to detect early manifestations such as extrapyramidal, depression and should stop treatment promptly. . For pregnant women, nursing mothers and young children, it has not been proven safe to use the drug. Therefore, it should be avoided and should be consulted with a doctor to weigh the benefits and risks of harm. Because it can cause drowsiness, care should be taken when operating machinery and vehicles. Alcohol and sedative drugs can increase the effect of drowsiness, so the combination should be avoided. Hagizin is a prescription drug, so it should be taken under the direction of a doctor. When taking medication, you need to consult your doctor to avoid improper use and cause unnecessary side effects.