What is Topolac us?

The main active ingredients in each 10g tube of Topolac US include:
Betamethasone dipropionate: 6.4 mg; Clotrimazol: 100 mg; Gentamicin sulfate equivalent to Gentamicin: 10 mg. And the system of excipients includes: Cetyl stearyl alcohol, Cetyl alcohol, Paraffin oil, Cremophor A6, Cremophor A25, Propylene glycol, Methyl Paraben, Tween 20, Butyl hydroxy toluene (BHT), Propyl paraben, apple flavoring - 500623 , RO water is just enough for 1 tube of 10g.
Topolac US drug belongs to the group of drugs for external use.
Betamethasone is a synthetic derivative of prednisolone.
Betamethasone in Topolac US is an adrenal corticosteroid with anti-inflammatory, anti-allergic properties, reducing the body's resistance to irritants. Clotrimazole is a synthetic derivative of imidazole and has a chemical structure similar to Miconazole, has broad-spectrum antifungal properties and is formulated for topical application, capable of inhibiting the growth of most microorganisms. pathogenic fungi in humans. Gentamicin in Topolac US is an antibiotic that is effective against susceptible bacteria.

Topolac US drug is indicated for the treatment of:
Corticosteroid-responsive atopic dermatitis when complicated by secondary infection (caused by bacteria or fungi sensitive to the components of the drug) or when the possibility of infected; Atopic dermatitis such as eczema (eczema). Topolac US medicine is only used by prescription of a doctor.

Dosage and time to use Topolac US drug for each specific case as prescribed by a doctor normally as follows: Apply a thin layer of Topolac US medicine to the diseased skin and apply it thoroughly, use 1-3 times/ day.

Contraindications of Topolac US drug in the following cases:
Patients with a history of hypersensitivity to any ingredient of Topolac US drug; Eczema otitis externa with perforated tympanic membrane; Skin ulcers; History of hypersensitivity to Aminoglycoside antibiotics such as: Streptomycin, Kanamycin, Gentamicin, Neomycin or Bacitracin;. Betamethasone should not be used in patients with diabetes, mental illness, gastric ulcer and duodenal ulcer, not used in bacterial infections, viral infections, systemic fungal infections.

Except for special cases, it is necessary to avoid applying Topolac US medicine to a large area of ​​skin, using Topolac US medicine for a long time or covering the wound with a bandage, because it may increase systemic drug absorption. The lowest possible dose of Betamethasone must be used to control the disease being treated, when the dose of Topolac US is reduced, the dose must be reduced gradually. When using systemic betamethasone must be very cautious in case of congestive heart failure, new myocardial infarction, hypertension, diabetes mellitus, epilepsy, glaucoma, hypothyroidism, liver failure, osteoporosis, stomach ulcer thickening, psychosis and renal failure; Children may be at increased risk for some unwanted effects of Topolac US , in addition Betamethasone may cause growth retardation; The elderly may also be at increased risk for unwanted effects of Topolac US . Tell the doctor if the patient develops increased irritation at the application area (redness, itching, burning, blisters, swelling) or signs of hypersensitivity; Because safety in pregnancy and lactation has not been established, Topolac US should only be used when the potential benefits outweigh the risks.

Because Topolac US medicine contains Betamethasone, it may interact with paracetamol, tricyclic antidepressants, oral antidiabetic drugs or Insulin, digitalis glycosides, Phenobarbital, Phenytoin, Rifampicin or Ephedrin, Coumarin anticoagulants.

During the use of Topolac US drug, patients may experience some of the following side effects:
Side effects of Topolac US drug due to Betamethasone rarely occur with the drug when applied topically: allergic dermatitis, urticaria, angioedema; Side effects of Topolac US due to Clotrimazol when used topically include local reactions (incidence >1%) including minor burns, irritation, allergic contact dermatitis, burning pain at the application site in skin or vagina; Side effects due to Gentamicin: No side effects have been reported when using gentamicin in topical form. Topolac US is a topical medication used in atopic dermatitis. To ensure the effectiveness of treatment and avoid side effects, users need to strictly follow the instructions of the doctor, professional pharmacist.
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