Zemaira Vial: Uses, indications and precautions when using

Zemaira Vial is used to treat emphysema caused by an inherited deficiency of alpha-1 proteinase (also known as alpha-1 antitrypsin). In patients with this condition, damage to the lungs occurs due to the enzyme elastase, a natural substance the body makes to kill bacteria that invade the lungs.
Under normal conditions, alpha-1-proteinase inhibits the activity of excess, unnecessary elastase. However, in people who don't make enough of this protein, overactivity of the enzyme elastase damages the lungs.
Zemaira contains the same active ingredient, which replenishes missing alpha-1-proteinase levels and helps patients prevent further lung damage.

Zemaira Vial is used intravenously, usually only once a week or as specified by a doctor. If you are using Zemaira at home, get instructions on how to prepare and inject the medication on the product packaging and from your healthcare provider. If any information about Zemaira is not clear, consult your doctor or pharmacist for guidance.
If the instructions for use of the drug require that Zemaira Vial be stored in the refrigerator, the patient should leave the medicine and solution at room temperature before each use. Note do not shake the drug mixture after it has been mixed because it may reduce the effectiveness of the drug Zemaira.
Before use, the patient should inspect the Zemaira medicinal product with the naked eye for precipitation or discoloration. Occasionally, a few small precipitates may remain in the Zemaira potion and they will be removed by the filter that comes with the medicine. If the Zemaira medicinal product is discolored, the patient must absolutely not use that vial.
The dose of Zemaira is prescribed by the doctor based on the patient's weight, health condition and response to treatment.
Use Zemaira medicine regularly and regularly to achieve the highest treatment effect. To help with memory, the patient should be given Zemaira injections at the same time each day by marking the reminder on the calendar. Patients should inform their doctor if their condition worsens after several weeks of treatment with Zemaira.

Common adverse effects of Zemaira include pain at the injection site, fever, dizziness, headache, drowsiness, numbness/tingling sensation on the skin, and muscle pain. If any of these signs of Zemaira persist or get worse, report them to your doctor or pharmacist immediately.
Zemaira is made from human blood components. Therefore, there is a very small chance that a patient may develop infections caused by Zemaira (including viral infections such as hepatitis, parvovirus B19) despite careful examination of blood donors, manufacturing processes, etc. Specialty and multiple tests are used to minimize this risk.
Patients should discuss the benefits and risks of Zemaira treatment with their doctor. Also, tell your doctor right away if you develop any signs of hepatitis or other infection, including persistent fever, sore throat, stuffy nose, unusual tiredness, unusual sleepiness, pain joints, persistent nausea/vomiting, stomach pain, abdominal pain, yellowing eyes/skin, dark urine.
Serious allergic reactions to Zemaira are very rare. However, patients should stop taking Zemaira and seek medical attention immediately if they notice any symptoms of an allergic reaction to Zemaira including: rash, hives, swelling, itching of the face. tongue/lips/throat, chest tightness, dizziness or trouble breathing.
The above is not a complete list of possible side effects of Zemaira Vial. If you notice other effects of Zemaira medicine not listed above, please contact your doctor or pharmacist for instructions.

Before treating emphysema with Zemaira Vial, tell your doctor or pharmacist if you have previously had an allergic reaction to alpha-1 proteinase or if you have any other allergic conditions. Zemaira Vial products may contain excipients that are inactive and may cause allergic reactions.
Before using Zemaira, please tell your doctor or pharmacist your previous medical history, especially:
Selective IgA deficiency with anti-IgA antibodies; Liver disease; Heart problems (such as heart failure). Zemaira can make people dizzy or drowsy, alcohol or marijuana are substances that make this dizziness or drowsiness worse. Therefore, do not drive, use machines, or do anything that requires alertness while taking Zemaira until it is safe to do so.
Since Zemaira is made from human blood, there is a very small chance that it can cause infection for the user. Patients should therefore be vaccinated with appropriate prior vaccinations (eg, for hepatitis A and B). At the same time, the handling of blood products from blood donors for the preparation of Zemaira requires special care to prevent virus infection.
During pregnancy, Zemaira should only be used when absolutely necessary after carefully discussing the risks and benefits with the treating doctor. It is not known whether Zemaira passes into breast milk, so nursing mothers should consult their doctor before using Zemaira.

The effects of some medicines may change if you take them at the same time as medicines or herbal products, which may increase your risk of serious side effects or may cause Zemaira to wear off. therapeutic effect.
Drug interactions can occur at a certain rate and your doctor or pharmacist will take measures to prevent or manage interactions by changing the way Zemaira is used or monitoring the patient closely.
To help your doctor or pharmacist provide the best care and treatment, please share with your doctor or pharmacist all the products you are using before starting treatment with Zemaira Vial. During treatment with Zemaira, patients should not start, stop or change the dose of any medication without their doctor's approval.
Laboratory tests and/or medical examinations (such as pulmonary function tests) should be performed periodically to monitor disease progression or detect side effects from Zemaira.
If you have missed a dose of Zemaira, ask your doctor or pharmacist immediately for a new dosing schedule.
Different brands of alpha-1 proteinase have different storage requirements. Consult your pharmacist on how to store Zemaira Vial, taking care not to freeze the medicine. After mixing Zemaira with the accompanying injection solution, do not keep the mixture in the refrigerator and use it within 3 hours. Do not flush Zemaira down the toilet or pour it down the drain unless it has expired or is no longer in use.
Knowing the information about the drug Zemaira before use always brings positive effects as well as reduces risks for patients. If you have any questions, you can send them to Vinmec International General Hospital to receive in-depth advice from a team of doctors and pharmacists with many years of experience.

Reference source: webmd.com