Causes of idiopathic thrombocytopenic purpura (ITP)

Immune thrombocytopenic purpura can occur in any population, both adults and children. For children, the disease usually begins after a viral infection and can go away on its own without treatment, but for adults, the disease is very likely to progress to chronic if not treated properly. .

1. What is idiopathic thrombocytopenic purpura?

Spontaneous thrombocytopenic purpura, also known as immune thrombocytopenic purpura, is a disease that presents a hemostasis disorder that can cause bruising or bleeding in the patient's body.
Bleeding occurs when the number of platelets (a component that helps blood clot and stop bleeding) is abnormally low.
Sự xuất huyết xảy ra khi số lượng tiểu cầu (thành phần giúp đông máu và cầm máu) thấp một cách bất thường

2. What causes idiopathic thrombocytopenic purpura?

Until now, the exact cause of thrombocytopenia bleeding has not been determined, which is why it is called “spontaneous”. However, according to some studies in patients with idiopathic thrombocytopenic purpura, it is because their immune system has a problem and attacks the body's own platelets because it thinks they are foreign objects. outside the body.
On average, the peripheral blood cell count is about 150,000 platelets per microliter of blood, but patients with idiopathic thrombocytopenic purpura usually have a platelet count less than 20,000. Patients will be in danger if the platelets drop below 10,000/1mm3.
When illness occurs in children, it may be due to a viral or mumps infection, the flu, or it may be due to an infection that has disrupted the immune system and caused decreased bleeding. immune platelets. This disease is very common in children, especially in the period from 2 to 9 years old, it is caused by:
Due to thrombocytopenia due to homologous antibodies Due to drugs and chemicals and some types of unknown cause serious infections, viral infections (influenza, measles, mumps, viral hepatitis), parasitic infections (malaria). In addition, idiopathic thrombocytopenia can also be caused by toxins and the effects of some drugs, drugs can be antipyretics, sedatives, flu drugs, antibiotics...
Bệnh giảm tiểu cầu tự phát còn có thể do độc chất và tác dụng của một số loại thuốc gây ra

3. Who is at risk for spontaneous thrombocytopenic purpura?

Spontaneous thrombocytopenic purpura can occur at any age, however, having the following factors may increase the risk of the disease, namely:
Gender: Women are at risk The chance of getting sick is twice as high as that of men Newly infected with the virus. For patients with immune thrombocytopenic purpura, it is necessary to avoid the use of drugs that can affect the function of platelets, participate in work and low-contact activities and absolutely do not play games. Sports can cause damage and cause bleeding. Each patient needs to actively combine the treatment regimen of the doctor with the building of a healthy lifestyle and eating regimen to promote health and not make the disease worse.

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