Cardiovascular physiology in general anesthesia

Anesthesia resuscitation includes all pre-anesthesia examinations. Accordingly, anesthesia, resuscitation, external resuscitation and anti-pain play a decisive role in the success of a surgery. Anesthesiologists also need to pay attention to the cardiovascular physiology and circulatory system of the patient because instability in the cardiovascular system can lead to complications during anesthesia or surgery, even death. dead.

First it is necessary to determine whether the physicochemical mechanism of the anesthetic or anesthetic properties will be related to the solubility of the drug in the biofilm. More specifically, the anesthetic will cause the membrane to stretch to a certain volume, which will form a state of anesthesia. In addition, this tension is related to the drug's response to protein. Changes in cell membrane structure affect neurotransmission at the brain's synapse and lead to coma.
It is essential in anesthesia to achieve an anesthetic blood concentration sufficient to depress the central nervous system. Patients with enough anesthesia will lose consciousness, lose sensation of movement, many reflexes are blurred and only activities such as heart, lungs, liver, and kidneys are left to maintain life.
In inhalation anesthesia, because the concentration of anesthetic gas in the alveoli is higher than in the blood, the anesthetic gas will diffuse through the alveolar-capillary membrane into the blood, causing the anesthetic concentration in the blood to increase gradually. The action of the heart at this time will promote the delivery of anesthetic to affect the cell membranes, affecting nerve transmission at the synapse, causing anesthesia.
In intravenous anaesthesia, the anesthetic will be injected directly into the vein at the time of induction of anesthesia, causing the concentration of anesthetic in the blood to immediately increase in proportion. After that, the anesthetic will gradually penetrate into the tissues, the patient will be anesthetized when the anesthetic concentration reaches the level of central nervous system depression.

Anesthesia and resuscitation activities for cardiovascular patients also have more attention than those of the general population. During the pre-anesthesia or post-anesthesia period, it is necessary to evaluate:
Duration and nature of surgery History of heart failure Patient's activities Preoperative electrocardiographic abnormalities and degree of left ventricular dysfunction ( EF) Accordingly, before surgery it is also necessary to evaluate factors such as:
Should antispasmodics be continued treatment (Beta blockers) The use of antiplatelet drugs (Aspirin) Replace with Calciparin An ACE inhibitor (Captopril, Enalapril) if used to prevent heart failure, continue to use it otherwise it will be replaced with Nifedipine if the goal is to lower blood pressure Do not apply preoperative blood sampling for transfusion

When performing anesthesia resuscitation, attention should be paid to the cardiovascular physiology and circulatory system of the patient to avoid dangerous complications during anesthesia that may occur to the patient.
Vinmec International General Hospital is one of the hospitals that strictly applies safe surgical anesthesia practice standards according to international guidelines. With a team of experienced anesthesiologists and nurses, along with modern equipment such as nerve detectors, ultrasound machines, Karl Storz difficult airway control system, anesthesia monitoring system GE's comprehensive AoA (Adequate of Anesthesia) including monitoring of anesthesia, pain and muscle relaxation will deliver high quality and safety, helping patients to have adequate anesthesia, not awake, no residual relaxant muscle after surgery. Vinmec Health System is also proud to be the first hospital in Vietnam to sign with the World Anesthesiology Association (WFSA) towards the goal of becoming the safest hospital for surgical anesthesia in Southeast Asia.