Contrast drug removal process

The article was written by Master, Doctor Nguyen Thuc Vy - Doctor of Radiology, Department of Diagnostic Imaging - Vinmec Nha Trang International General Hospital

Contrast agents are substances used to enhance the contrast level of body structures or fluids during diagnostic imaging. Contrast containing Iodine is classified into 2 types: Contrast containing Iodine oil-soluble and Contrast containing Iodine water-soluble.

In patients with normal renal function, the excretion of contrast is almost entirely through the urinary tract. Approximately < 1% of contrast agent is excreted by other routes, mainly via the hepatobiliary tract and the small intestine.
When renal function declines, the liver becomes the main replacement organ for contrast excretion through the amount of contrast excreted via the biliary tract. Very small amounts of contrast medium are also excreted through the small intestine, sweat, saliva, tears, and gastric juices. By analyzing the amount of contrast material in the stool, it is shown that 20-50% of the contrast is eliminated in the feces in patients with renal failure.

In subjects with normal renal function, the urinary excretion of contrast material is 12% after 10 minutes, 50% after 1 hour, 83% after 3 hours and almost 100% after 24 hours. Contrast clearance time will be longer in patients with reduced renal function.

Drinking a lot of water after contrast injection will help the contrast to be better eliminated through the urine and reduce the risk of kidney toxicity.
In some cases, for patients with impaired kidney function who need to use contrast medium to support the diagnosis, the doctor will give fluids to the patient before and after using contrast to reduce the risk of kidney toxicity. .

Drinking a lot of water after contrast injection will help the contrast to be better eliminated through the urine and reduce the risk of kidney toxicity.
In some cases, for patients with impaired kidney function who need to use contrast medium to support the diagnosis, the doctor will give fluids to the patient before and after using contrast to reduce the risk of kidney toxicity. .
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MORE:
What is Contrast? What is a CT scan? In which cases need contrast injection? Contrast in computed tomography (CT Scan)