What is type 2 high proline?

High proline causes birth defects in the baby at birth. According to research, there are 2 types of high proline: high proline type 1 and high proline type 2; where each would represent a genetic defect related to the metabolism of the amino acid, proline. So what is type 2 high proline?

1. What is type 2 high proline?

According to research results from doctors and clinical researchers, there are two types of proline, called type 1 and type 2.
Differences in signs of defects Congenital defects cause children as well as factors such as blood proline levels, amino acid metabolism should be divided into 2 types: High proline type 1 and high proline type 2. In which:
High proline type I (HP-I) is characterized by high blood proline levels. It is caused by a deficiency of proline oxidizing enzyme, which breaks down proline (metabolism). Type I high levels of proline usually do not have the same clinical manifestations as type 2. in children such as mild mental retardation, along with convulsions.

Cao prolin tuýp 2 có thể kèm triệu chứng chậm phát triển trí tuệ nhẹ đi cùng co giật.

2. Symptoms of high proline disease type 2

Hyperprolinear disease type 2 is a rare metabolic disorder that results in a delta-pyrroline-5-carboxylate (P-5-C) dehydrogenase deficiency. Can occur in both men and women.
Common symptoms that occur with type II hyperprolineopathy are:
Inherited recessive gene Elevated urine hydroxyproline levels High urine glycine levels Children with intellectual disability When the tests are done, the results showed elevated proline markers and increased urinary P-5-C levels. (The proline level in normal human blood is about 450 units, while the proline level in a patient diagnosed with type 2 hyperprolineemia can reach 1,900-2,000 units.) This is the basis for the conclusion that the patient has type 2 high proline.

thiểu năng trí tuệ — Thiểu năng trí tuệ là một triệu chứng của bệnh cao prolin tuýp 2

3. Can type 2 hyperprolineosis be treated?

There is no specific treatment for type 2 hyperprolineemia. In general, people with type 2 hyperprolineemia have symptoms that are usually mild and do not require treatment. You can treat type 2 hyperprolineosis by working to reduce your proline levels through your diet.
High proline type 2 does not require treatment, but parents still need to take their children for regular check-ups and exams for doctors to consult, check and assess their health status. Parents should take their children to reputable medical centers and treatment facilities to ensure safety.

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Bài viết này được viết cho người đọc tại Sài Gòn, Hà Nội, Hồ Chí Minh, Phú Quốc, Nha Trang, Hạ Long, Hải Phòng, Đà Nẵng.