Uses of Farydak

Farydak is a drug in the class of histone deacetylase inhibitors, used in the treatment of cancer. Follow the article to better understand the use of Farydak medicine.

Farydak is a chemotherapy drug that slows or reverses the growth of cancer cells, so Farydak is used to treat multiple myeloma.
The main ingredient of Farydak is Panobinostat.
Panobinostat is in a group of anti-cancer therapies known as histone deacetylase (HDAC) inhibitors. It does this by blocking certain tumor suppressor genes, as well as other genes involved in cell cycle progression, cell proliferation, programmed cell death (apoptosis), and differentiation. (transformation of immature cells into specialized cells).

The drug Farydak produced in the form of capsules. Take Farydak with a full glass of water, about 240ml. Do not open, crush or chew the capsule.
A cycle of treatment with Farydak is usually taken every 1 day. Take 3 doses per week for the first 2 weeks, then stop taking the drug for 1 week and then continue taking it. Dosage may be adjusted according to the patient's medical condition, age, gender, and response to treatment. Never increase the dose on your own without consulting your doctor.
Should take the medicine at the same time every day.
If you miss a dose, take it as soon as you remember, Farydak can be taken within 12 hours after the fixed dosing time. If the 12 hour period is over, skip the missed dose and take the next dose.
Note:
Sour fruits such as grapefruit, pomegranate and star fruit can affect the effectiveness of the medicine, so should be avoided. Certain medicines including Boceprevir, Clarithromycin, Indinavir, Intraconazole, and Ketoconazole may affect this medicine. Therefore, it is necessary to inform the doctor, pharmacist of the drugs and dietary supplements that are being used.

Store the medicine at room temperature and in a dry place Keep the Farydak container out of the reach of children and pets. Caregivers should consider wearing gloves or pouring medication directly from the container into the lid, cup, or directly into the patient's hand to avoid touching the tablet. Hands should be washed before and after giving medication to the patient. Pregnant or nursing women should not give the medicine to sick people. Do not flush medicine down the toilet or throw it in the trash.

Some common symptoms that often occur after using Farydak medicine include:
Diarrhea: Diarrhea caused by Farydak medicine can lead to dehydration. The physician in charge should be informed if the patient experiences stomach cramps or passes more than 3 stools per day. Feed the patient low-fiber foods, white rice, boiled chicken. Avoid raw fruits, vegetables, whole grain breads, cereals and seeds. Drink 8-10 glasses of plain, non-caffeinated water to prevent dehydration. Cardiovascular problems: This drug may cause an irregular heartbeat or heart attack. Your doctor will order blood tests and an electrocardiogram (ECG) before you start taking this medicine and as needed during treatment. If you see signs of chest pain, irregular heartbeat, feeling light-headed, dizzy or short of breath, leg swelling, you should immediately notify your doctor for examination and timely treatment. Electrolyte abnormalities: Farydak may affect the normal levels of electrolytes (potassium, magnesium, calcium, etc.) Levels will be monitored with a blood test. If your levels are too low, your doctor may prescribe specific electrolytes to be given intravenously or orally. Do not take any supplements without consulting your doctor first. Thrombocytopenia: Platelets help with blood clotting, so when the platelet count drops there is a higher risk of bleeding. If you notice any bruising or excessive bleeding, including nosebleeds, bleeding gums, or blood in your urine, notify your doctor immediately. If the platelet count gets too low, a platelet transfusion may be needed. Fatigue: Fatigue is very common during cancer treatment and is a feeling of exhaustion that often does not subside with rest. During cancer treatment and for a period of time afterward, patients may need to adjust their schedule to manage fatigue. Plan time to rest during the day and save energy for more important activities. Exercise can help combat fatigue, consult your doctor for some more ways to deal with this side effect. Nausea, vomiting: Inform your doctor about your current condition and may prescribe medication to help control nausea and vomiting. Infections and low white blood cell counts (leukopenia or neutropenia): During treatment, the white blood cell count may drop, putting the person at higher risk of infection. You should notify your doctor or nurse immediately if you have symptoms such as fever (temperature higher than 38°C), sore throat or cold, difficulty breathing, cough, burning when urinating, or pain that does not heal. . Peripheral edema: Peripheral edema is swelling of the extremities due to fluid retention. It can cause swelling of the hands, arms, legs, ankles, and feet. The swelling may become uncomfortable. Tell your doctor if you are experiencing any new or worsening swelling. Anorexia: Cancer treatment can affect appetite, and in some cases, treatment side effects can make it difficult to eat. Divide into many small meals throughout the day or for 3 main meals. If the person is not eating enough, choosing nutritional supplements can be helpful. High fever: Fever can be a side effect of Farydak. Tell your doctor right away if your fever is 38°C or higher. Less common, but other possible side effects associated with Farydak use include:
Hepatotoxicity: This drug can cause liver toxicity. Tell your doctor if you notice yellow skin or eyes, dark or brown urine, pain in the abdomen, as these could be signs of liver toxicity. Bleeding: This medication may cause bleeding and take longer than usual to stop bleeding. Notify your doctor if you see any signs of bleeding. Low red blood cell count (anemia): Red blood cells are responsible for transporting oxygen to tissues in the body. When the red blood cell count is low, it causes fatigue. Tell your doctor if you feel short of breath or have chest pain. If the count is too low, a blood transfusion may be given. Exposure to Farydak to an unborn baby can cause birth defects, so it is not advisable to become pregnant while taking this medicine. For women, effective contraception is needed during treatment and for at least 3 months after treatment. For men, effective contraception is needed during treatment and for at least 6 months after treatment. Even if you miss your period or don't ejaculate, it's still possible to conceive. Stop breastfeeding while taking this medicine.
Farydak's main use is to treat multiple myeloma. However, you should only take this medicine with your doctor's prescription to reduce the risk of unwanted side effects.

Reference source: ncolink.org