Linagliptin: Uses, indications and cautions when using

Linagliptin is a drug that is used to control high blood sugar in patients with type 2 diabetes. From there, it helps prevent complications of diabetes such as blindness, kidney damage, problems with diabetes. neurological problems, limb necrosis, sexual dysfunction,...

What does Linagliptin do? Linagliptin, sold under the brand name tradjenta, is used to control high blood sugar in people with type 2 diabetes. Linagliptin is used with an appropriate diet and exercise program and can also be combined with other medications to control high blood sugar.
Controlling high blood sugar can help prevent complications of diabetes such as blindness, kidney damage, nerve problems, gangrene of the extremities and problems with sexual function. Linagliptin is a diabetes medication that works by increasing levels of a natural substance called incretin. Increasetins help control blood sugar by increasing the body's natural insulin, especially after meals. Besides, Linagliptin also reduces the amount of sugar that the liver makes.

Linagliptin is to be taken by mouth with or without food as directed by your doctor, usually once daily. The dosage is based on your medical condition, response to treatment, and other medications you are taking. Check your blood sugar regularly while taking Linagliptin to prevent blood sugar from getting too high or too low. Tell your doctor right away if your blood sugar is abnormal.
Use Linagliptin regularly to get the most benefit from it. To make it easier for you to remember when to take your medicine, take it at the same time each day. Never increase the dose or abuse the drug for longer than prescribed. This not only makes the condition improve faster, but also increases the risk of unwanted effects.

Some unwanted effects that may occur when using Linagliptin include:
Dizziness Drowsiness Joint pain Unusual blistering of the skin Signs of heart failure: difficulty breathing, swelling ankles or feet, sudden weight gain sudden, unusual tiredness,... Serious side effects: signs of pancreatic disease (such as nausea, vomiting that won't stop, stomach pain, abdominal pain that may spread to the back) Symptoms of increased Blood sugar includes thirst, increased urination, drowsiness, confusion, rapid breathing, and fruity breath. If these symptoms occur, notify your doctor immediately. Your doctor may need to adjust your diabetes medications. Linagliptin does not cause hypoglycemia, but it can happen when Linagliptin is prescribed with other diabetes medicines or if you do not consume enough calories from food or exercise unusually heavy. Talk to your doctor or pharmacist about whether your other diabetes medications need to be reduced. Symptoms of hypoglycemia include hunger, blurred vision, tremors, sudden sweating, heart palpitations, dizziness or tingling in the hands/feet. Carrying sugar glucose is a good habit tablets or gel to treat low blood sugar. If you don't have these reliable forms of glucose, get your blood sugar up quickly by eating a quick source of sugar like table sugar, candy, honey, or drinking fruit juice. Inform your doctor immediately of your reaction and use of this product. To help prevent hypoglycemia, eat regularly scheduled meals and do not skip meals. Check with your doctor or pharmacist to find out what to do if you miss a meal.

Before prescribing, doctors always weigh the benefits of Linagliptin to outweigh the risk of side effects. However, some cases of using Linagliptin may still occur unwanted effects. Therefore, when you see unusual signs, especially when an allergic reaction occurs such as rash, itching or swelling of the face, tongue, throat, severe dizziness, difficulty breathing, ... In school In this case, the patient should immediately notify the doctor for prompt medical intervention.

Some notes when using Linagliptin include:
Report a history of allergy to Linagliptin or any other allergies. Linagliptin medicinal products may contain inactive ingredients that can cause allergic reactions or other serious problems. Inform medical history such as pancreatic disease (pancreatitis), gallstones, heart failure, etc. Do not drive, use machinery or perform any activity that requires alertness or vision. clear until you are certain that the operations can be performed safely. Because Linagliptin can cause blurred vision and dizziness. To reduce the risk of dizziness get up slowly or when changing positions from lying down to sitting... Do not drink alcohol while taking Linagliptin as it may increase your risk of developing low blood sugar and high ketone levels. Before surgery, talk to your doctor or dentist about all the products you are using including over-the-counter medicines, prescription drugs, vitamins, and herbal products. Older adults may be more sensitive to the side effects of the drug, especially kidney problems, dehydration, dizziness, and low blood pressure. During pregnancy, Linagliptin should be used only when clearly needed. Pregnancy can cause or worsen diabetes. Discuss your plan with your doctor to manage gestational diabetes. Your doctor may change your diabetes treatment regimen during pregnancy (eg, your diet and medications, including insulin). It can be harder to control blood sugar when your body is under stress (such as from a fever, infection, injury, or surgery). Also, if you eat little or are unable to eat due to these conditions or any illness, this may lead to high ketone levels while you are taking this medicine. Consult your doctor as this may require changes to your treatment plan, medications, or blood sugar or ketones testing. Attend a diabetes education program to learn more about managing your diabetes with medication, diet, exercise, and regular checkups. Learn the symptoms of high or low blood sugar and how to manage low blood sugar. Check your blood sugar regularly as directed by your healthcare provider. Keep all follow-up appointments and tests (eg, kidney function tests, blood pressure, blood glucose, hemoglobin A1c, cholesterol, ketones) should be performed periodically to monitor response to treatment. or check for side effects. If you forget to take a dose of Linagliptin, take it again as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue taking your next dose at the same time as the first dose. Absolutely do not use more than double the dose than the treatment regimen. Linagliptin overdose can cause serious symptoms such as severe dizziness, fainting,...

Drug interactions can decrease the effectiveness of Linagliptin, or increase the effect of unwanted effects. Tell the doctor about all other medications the patient takes, including prescription and over-the-counter medicines, vitamins, and herbal products. Do not start, stop, or change the dose of any medicine without your doctor's consent.
Beta-blockers can stop the fast, pounding heartbeat you usually feel when your blood sugar gets too low (hypoglycemia), eg metoprolol, propranolol, glaucoma eye drops like timolol,. .. Other symptoms of low blood sugar, such as dizziness, hunger or sweating, are not affected by Linagliptin medicines.
Many medications can affect blood sugar levels, making it harder to control. Before starting, stopping, or changing any medication, talk to your doctor or pharmacist about how medications can affect blood sugar readings. So check your blood sugar as often as directed and share the results with your doctor. Tell your doctor right away if you have symptoms of high or low blood sugar. Your doctor may need to adjust your diabetes medication, exercise program, or diet.

Store Linagliptin at room temperature, away from moisture and light. Do not store Linagliptin in a humid place or in the freezer. Each medicine will have different storage methods, so read the instructions on the packaging for Linagliptin carefully, or ask your pharmacist. Keep Linagliptin out of the reach of children and family pets. When the medicine is past its expiry date or cannot be used, dispose of it properly. Do not arbitrarily dispose of Linagliptin into an environment such as a water pipe or toilet unless requested to do so. Ask your waste disposal company or pharmacist for advice on how to safely dispose of Linagliptin to help protect the environment.

In summary, Linagliptin is a drug that is used to control high blood sugar levels in patients with type 2 diabetes. From there, it helps prevent diabetes complications such as blindness, kidney damage. , nerve problems, limb necrosis, impaired sexual function,... However, Linagliptin can cause some unwanted effects and drug interactions, so tell your doctor. medications you are taking to reduce your risk of side effects and increase the effectiveness of your treatment.

Reference source: webmd.com