Morphine SULFATE ER Capsule, Extended Release Multiphase 24 hr: Uses, indications and precautions for use

Pain relievers have many types with different pain-relieving effects. Among them is the drug Morphine SULFATE ER which is used in situations of severe pain. What is Morphine SULFATE ER?

What is Morphine SULFATE ER? This is a long-acting medication that relieves severe pain (like cancer pain). This is a class of pain relievers that belong to the opioid analgesic family. The mechanism of pain relief of Morphine SULFATE ER is to help reduce the perception and response of the body to pain.
Morphine SULFATE ER Bulk (90 and 120mg capsules) is only used when the body has tolerated a large amount of opioid pain relievers. Overdosage can cause complications, even death), especially in people who have never used opioids.
Morphine SULFATE ER should not be used in cases of mild pain or short-term pain. This group of drugs is not used too often, only when absolutely necessary.

Read the instructions for using Morphine SULFATE ER carefully before starting or every time you receive a new medicine. Use Morphine SULFATE ER regularly as prescribed and directed by your doctor, do not arbitrarily use for sudden pain.
Morphine SULFATE ER can be taken before or after a meal, usually once a day (taken every 24 hours). In case the patient has nausea and vomiting, it can be taken after meals. Talk to your doctor about ways to reduce nausea (such as lying down for 1 to 2 hours and limiting exercise after taking the medicine).
When using, should swallow the entire capsule of Morphine SULFATE ER. Elderly adults who have difficulty swallowing the tablet may open and sprinkle the tablet ingredients on a spoonful of water, then swallow the entire mixture right away without chewing.
After taking the medicine, you should rinse your mouth clean. Absolutely do not chew this mixture or prepare the mixture for too long before drinking. Do not apply this method to children. As an alternative, consult your doctor for an alternative form of Morphine SULFATE ER. In particular, due to the risk of overdose, absolutely do not use Morphine SULFATE ER through a nasogastric tube.
Dosage of Morphine SULFATE ER depends on the patient's health status and response to treatment. Do not arbitrarily increase the dose, use the drug regularly or exceed the prescribed time. When stopping the drug, follow your doctor's instructions.

The maximum recommended dose of Morphine SULFATE ER is 1600mg every 24 hours. The maximum overdose increases the risk of kidney damage due to the fumaric acid component of the drug.
Before using Morphine SULFATE ER, consult with your doctor or pharmacist about whether the patient should stop or change the way other opioid medications are taken. Other pain relievers (such as acetaminophen, ibuprofen) may be prescribed with Morphine SULFATE ER. Ask your doctor about how to safely use morphine with other medicines.
Abrupt discontinuation of Morphine SULFATE ER can cause discontinuation syndrome, especially when the patient has been taking it for a long time or in high doses. To prevent this, your doctor must reduce your dose slowly. Contact a physician immediately if a patient shows signs of discontinuation syndrome, including:
Restlessness; Mood changes (such as anxiety, insomnia, suicidal thoughts); Watery eyes, runny nose; Nausea; Diarrhea; Sweating; Muscle pain or sudden changes in behavior. Patients who use Morphine SULFATE ER for a long time may lose its analgesic effect. Ask your doctor if the medicine is not working or is not working as expected.
This is a group of drugs that can be addictive, especially in people who have used or have a substance use disorder (such as abusing or addicted to drugs or alcohol). Take medication exactly as prescribed by your doctor to reduce the risk of addiction. Report your pain if it does not decrease or gets worse while using Morphine SULFATE ER.

Possible side effects when taking Morphine SULFATE ER:
Nausea, vomiting; Constipation; Lightheadedness, dizziness or drowsiness. Some side effects can be reduced with the use of Morphine SULFATE ER for a while. If this side effect persists or gets worse, you should report it to your doctor right away.
To relieve constipation, patients should get enough fiber, drink enough water and exercise. Patients may need to use laxatives as prescribed by their doctor.
To reduce dizziness and lightheadedness, change position slowly when switching from sitting or lying down to standing.
If you have any of the following serious side effects you should contact your doctor, including:
Sleep apnea (sleep apnea); Mental or mood changes (such as agitation, confusion, hallucinations) Severe stomach or abdominal pain; Difficulty urinating; Decreased adrenal gland activity (such as loss of appetite, unusual tiredness, weight loss); Faint; Convulsions; Respiratory disorders such as slow shallow breathing; Lethargy, difficult to wake up. Morphine SULFATE ER rarely causes severe allergic reactions. However, call 911 if you have any symptoms of a serious allergic reaction, including: generalized rash, itching or swelling of the face, tongue, or throat, dizziness, trouble breathing.

Report any allergies to Morphine SULFATE ER or other opioid pain relievers (such as codeine) or any other allergies to your doctor.
Before prescribing Morphine SULFATE ER, the doctor or pharmacist needs to know the previous medical history, including:
Brain abnormalities (such as head injury, tumor, epilepsy); Respiratory abnormalities (eg, asthma, sleep apnea, chronic obstructive pulmonary disease); Kidney disease, liver disease; Mental and mood disorders (such as confusion, depression); Personal or family history of substance use (including drug or alcohol abuse or addiction); Gastrointestinal diseases (such as constipation, infectious diarrhea, paralytic ileus); Difficulty urinating (such as an enlarged prostate gland); Pancreatitis, gallbladder disease. Morphine SULFATE ER may cause dizziness or drowsiness. Alcohol or drugs will make the patient more dizzy or drowsy. Do not do work that requires concentration or use of alcohol.
The elderly are susceptible to the side effects of Morphine SULFATE ER, especially confusion, dizziness, drowsiness and slow shallow breathing.
Pregnant women only use Morphine SULFATE ER when absolutely necessary because it can harm the unborn baby. Talk to your doctor about the risks and benefits of using Morphine SULFATE ER.
Morphine SULFATE ER may pass into breast milk and cause unwanted effects on a nursing infant. Tell your doctor right away if your baby shows signs of abnormality, stops feeding, or has trouble breathing.

Drug Interactions Morphine SULFATE ER may decrease the effects or increase the risk of serious side effects. Tell and share with your doctor or pharmacist all the medicines you are taking (including prescription, non-prescription and herbal medicines).
Do not start, stop or change the dosage of any medicine without consulting your doctor.
Products that may interact with Morphine SULFATE ER , including:
Alcohol products (such as cough and cold syrup); certain pain relievers (such as pentazocine, nalbuphine, butorphanol); Naltrexone. The risk of serious side effects (slow shortness of breath, drowsiness, severe dizziness) is increased when Morphine SULFATE ER is used together with other products with the potential to cause drowsiness or breathing disturbances.
Talk to your doctor about medications you are taking such as other opioid pain relievers such as: cough suppressants (codeine, hydrocodone), alcohol, marijuana, sedatives or anxiety relievers (such as alprazolam, lorazepam, zolpidem) , muscle relaxants (such as carisoprodol, cyclobenzaprine) or antihistamines (such as cetirizine, diphenhydramine). In addition, you need to be careful when:
Morphine SULFATE ER falsifies the results of some tests (including amylase, lipase). Morphine SULFATE ER is only used to treat pain at the present time, do not use it to treat other conditions without a doctor's prescription. Therefore, ask your doctor or pharmacist about stocking up on naloxone for opioid overdose. Educate family or members about the signs of an opioid overdose and how to manage it.
Morphine SULFATE ER is a pain reliever that is indicated in some cases. In order for the drug to work best as well as avoid side effects, the patient needs to follow the instructions for using the drug or as advised by the doctor or pharmacist.

Reference source: webmd.com