Uses of Acizit


Acizit belongs to the group of Macrolide antibiotics commonly used in the treatment of diseases such as respiratory tract infections, skin, soft tissue and genital tract infections. The use of the drug must comply with the prescription from the doctor to bring effectiveness and ensure safety for health.

1. What is Acizite?


The drug Acizit contains the active ingredient Azithromycin. This is an active ingredient in the Macrolide group of antibiotics that works to prevent the growth and outbreak of bacteria. Therefore, drugs are often used to treat infections caused by bacteria.
According to experts, the active ingredient Azithromycin is sensitive to bacteria such as Streptococcus pneumonia, Haemophilus parainfluenzae, Clostridium perfringens, Borrelia burgdorferi,...

2. Indications and contraindications of the drug Acizit


Acizit is commonly used in the treatment of infectious diseases caused by susceptible bacteria such as:
Patients with lower respiratory tract infections including bronchitis, pneumonia, skin and soft tissue infections, ear infections Between. Patients with upper respiratory tract infections such as sinusitis, pharyngitis and tonsillitis. However, Acizit should only be used in patients who are allergic to penicillin because it increases the risk of drug resistance. In addition to the above cases, Acizit is also indicated for use in the following cases:
Patients with uncomplicated genital tract infections caused by Chlamydia trachomatis. Patients with uncomplicated genital tract infections due to non-multiresistant Neisseria gonorrhoeae (use this drug only after ruling out concomitant Treponema pallidum infection). Some other cases are indicated to use Acizit include:
Using the drug in the prevention of Mycobacterium avium - intracellulare (MAC) infection in HIV patients. The drug is used alone or in combination with rifabutin. Used in the treatment of conjunctivitis caused by Chlamydia trachomatis (trachoma). Acizit is contraindicated in the following cases:
Patients with hypersensitivity to Azithromycin, Erythromycin or any antibiotic of the Macrolide group. Contraindicated in patients allergic to any ingredient of the drug Acizit.

3. How to use and dose of Acizit


Acizit is used orally, you should drink it directly with filtered water. Absolutely do not break, crush or dilute the drug because it will reduce the effect of the drug.
Dosage of Acizit refer to the following:
* Dosage of Acizit for adults:
Patients with pharyngitis and tonsillitis caused by Streptococcus pyogenes use a dose of 500mg on the first day, from day 2 to day 5 reduced to 250mg x 1 time/day. Patients with acute sinusitis caused by H.influenzae, M.catarrhalis or S. pneumoniae used at a dose of 500mg x 1 time/day, orally for 3 days. Patients with acute superinfection in chronic obstructive pulmonary disease (COPD) used a dose of 500mg on the first day, from day 2 to day 5 reduced to 250mg x 1 time / day. Patients with community-acquired pneumonia use a dose of 500mg on the first day, from day 2 to day 5 reduce to 250mg x 1 time / day. Patients with uncomplicated skin infections and skin structure infections used a dose of 500mg on the first day, from day 2 to day 5 reduced to 250mg x 1 time / day. Patients with chancroid (genital ulcer caused by Haemophilus ducreyi) used a single dose of 1g. Urinary tract infections and cervicitis use a single dose of 1g. MAC (Mycobacterium avium) infection in HIV-infected patients for primary prevention is administered at a dose of 1.2g once weekly. It can be used as monotherapy or used in combination with Rifabutin at a dose of 300mg/day. Patients with disseminated MAC infection used a dose of 600mg x 1 time/day in combination with Ethambutol 15mg/kg/day. Use Acizit to prevent recurrence of disseminated MAC infection with a dose of 500mg x 1 time/day in combination with Ethambutol 15mg/kg/day with or without Rifabutin 300mg x 1 time/day. Patients with HIV-negative MAC (Mycobacterium avium) infection (lung infection) use 250mg/day or 500mg 3 times/week in combination with Rifabutin 300mg/day or Rifampicin 600mg/day and Ethambutol 25mg. /kg/day for 2 months. * Dosage for children:
Use the drug in the first day at a dose of 10mg/kg. The next days use at a dose of 5mg/kg x 1 time/day, lasting for 5 days.

4. Side effects of the drug Acizit


During the use of Acizit, some common side effects include: Digestive disturbances, transient increase in liver enzymes, rash, headache, dizziness, reversible hearing loss.
In addition, patients may experience some less common side effects such as: Fatigue, headache, dizziness, drowsiness, flatulence, indigestion, loss of appetite, rash, itching. In particular, the drug Acizit has the risk of causing vaginitis, cervicitis, anaphylactic reactions, angioedema, elevated transaminase enzymes in the body, and transient neutropenia.

5. Drug interactions


Acizit has the risk of interacting with some of the following drugs:
Concomitant use with ergot derivatives will have the risk of poisoning the user. Acizit should be taken at least 1 hour before or 2 hours after taking antacids. When using Acizit with drugs containing Cyclosporine, it is necessary to monitor the concentration and adjust the dose of Cyclosporin accordingly. When using Acizit with drugs containing Digoxin concurrently, it is necessary to monitor the concentration of digoxin because of the potential to increase the concentration of digoxin.

6. Precautions while using Acizit


Active ingredients in Acizit are eliminated mainly by the liver, so it should be used with extreme caution in patients with impaired liver function. Care should be taken when administering the drug to patients with a glomerular filtration rate less than 10 mL/min. Acizit is only used for a short time, so patients absolutely do not prolong the time of taking the drug without a request from the doctor. The drug should be discontinued when symptoms do not improve after 5 days of regular use, develop an allergic reaction or develop serious side effects. Above is some information about the drug Acizit that readers can refer to. Note, Acizit is a prescription drug, patients need to use the drug as prescribed by the doctor, absolutely do not self-treat at home. If you have any questions about this drug during use, you can discuss it with your doctor to get specific answers.

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