Uses of Afocical

Afocical drug whose main ingredient is Atorvastatin calcium, commonly used in the treatment of dyslipidemia... Let's learn about the use of Afocical in the article below.

Afocical is manufactured by Withus Pharmaceutical Co., Ltd, Korea and circulated on the market with registration number VN-21122-18. Afocical is a prescription drug and is classified as a cardiovascular drug. The main active ingredient of Afocical is Atorvastatin calcium.
Dosage form: Film-coated tablets, each containing Atorvastatin calcium and other excipients of the manufacturer.
Packing form: Box of 3 blisters x 10 tablets and drug instruction sheet.

Atorvastatin is a selective competitive inhibitor of 3-hydroxy-3-methylglutarylcoenzyme A reductase (HMG-CoA reduetase), which converts FIMG-CoA to mevalonate. Therefore, Atorvastatin has the effect of preventing the synthesis of cholesterol in the liver, stimulating the synthesis of LDL-cholesterol receptors (low-density lipoproteins), increasing the transport of LDL-cholesterol from the blood. Atorvastatin has the strongest LDL-lowering effect of any drug taken alone.

Afocical is usually indicated in the following cases:
Complementary to the diet to reduce total cholesterol, LDL-Cholesterol, apolipoprotein B, triglycerides, and increase HDL-Cholesterol in patients with hypercholesterolemia. Addition to the same diet in patients with type III hyperlipidemia unresponsive to diet and in patients with high triglycerides (type IV). Complementary diet to reduce total cholesterol and LDL-Cholesterol in patients with homozygous familial hyperlipidemia. Prevention of cardiovascular events. Contraindicated in the following cases:
Hypersensitivity to any component of the drug Afocical. Progressive liver disease or unexplained persistent elevations in serum transaminases. Pregnant. Breastfeeding women.

Afocical is a prescription drug, so patients can only use it when prescribed by a doctor and must adhere to the treatment schedule, do not arbitrarily stop the drug, change the dosage and route of medication. At the same time, Afocical should not be shared with others or given to others to use even if they have the same diagnosis.
Dosage:
Treatment of heterozygous familial and non-familial hypercholesterolemia, mixed dyslipidemia: Start with a dose of 10-20mg/time/day. For patients requiring a large reduction in LDL-Cholesterol (> 45%) can be started with a dose of 40 mg once a day. The therapeutic dose range of Afocical is 10 - 80 mg/time/day. During treatment or when increasing the dose, it is necessary to assess the blood lipid indexes within 2-4 weeks to adjust the dose accordingly. Treatment of homozygous familial hypercholesterolemia: 10 - 80 mg/day, in combination with other lipid-lowering measures. Combination therapy: Afocical can be combined with Resin to increase the effectiveness of treatment. No dose adjustment of Afocical is required in patients with renal impairment. How to use: Afocical is prepared in the form of tablets and taken orally, can be taken at any time of the day, regardless of the meal.
How to deal with forgetting a dose of Afocical?
When you miss a dose, take another dose instead. If it is almost time for the next dose, skip the dose, do not increase the dose, or double the dose to make up for the missed dose. How to deal with an overdose of Afocical?
Overdosage of Atorvastatin can cause some symptoms such as increased neuromuscular sensitivity, convulsions. There is no specific treatment for Atorvastatin overdose, therefore symptomatic and supportive treatment should be instituted. Atorvastatin is strongly bound to plasma proteins, so hemodialysis is not significantly effective. When detecting a patient with signs of an overdose of Afocical, it is necessary to quickly take them to the nearest emergency center for treatment. Family members are advised to bring all medications the patient has taken before to support the diagnosis.

In addition to the therapeutic effect, Afocical medicine may cause some unwanted effects during use such as:
Common: Nasopharyngitis, allergies, hyperglycemia, headache, dizziness, paresthesia , drowsiness, mental confusion, memory loss, angina pectoris, angina, constipation, flatulence, dyspepsia, nausea, diarrhea, myalgia, arthralgia, muscle spasms, joint swelling, back pain, ... Uncommon: Hypoglycemia, weight gain, loss of appetite, nightmares, insomnia, blurred vision, tinnitus, vomiting, abdominal pain, belching, pancreatitis, hepatitis, urticaria, rash skin, itching, hair loss, muscle fatigue, fatigue, asthenia, chest pain, dengue fever, peripheral edema... Rare: Thrombocytopenia, peripheral neuropathy, mental disorders, cholestasis, angioedema, dermatitis, Stevens-Johnson syndrome, myositis, rhabdomyolysis, ... Very rare: Anaphylaxis, hearing loss, liver failure, gynecomastia in men,... Frequency unknown Rate: Immune-mediated necrosis, ... How to deal with adverse effects caused by Afocical:
Changes in liver enzyme levels in Serum g serum levels often occur in the first months of treatment with Afocical, patients with high aminotransferase levels should have liver function tests to monitor treatment until abnormalities return to normal. If liver enzymes increase more than 3 times the normal limit, treatment must be discontinued. Treatment should be discontinued when CPK levels are markedly elevated, above 10 times the upper limit of normal, and if myopathy is diagnosed or suspected. In addition, patients may experience other side effects that have not been reported or studied when using Afocical. Therefore, contact your doctor as soon as you have any unusual symptoms while using Afocical.

In order to use Afocical safely and effectively, to avoid drug interactions, patients need to list and inform their doctors about all medications they are taking to treat other diseases. At the same time, it is necessary to consult a doctor about the use of certain foods and drinks (such as alcohol, stimulants, fermented foods, etc.) because drug-food interactions may occur. products during treatment with Afocical.
Drugs that can interact with Afocical such as:
When co-administered with Atorvastatin with anticoagulants, Indandione will increase bleeding time or prothrombin time. Therefore, it is necessary to monitor prothrombin time in patients receiving concomitant anticoagulants. The drugs Cyclosporine, Erythromycin, Gemfibrozil, immunosuppressants, Niacin: When used in combination with Atorvastatin will increase the risk of myopathy. Digoxin: Co-administration with Atorvastatin resulted in a slight increase in serum digoxin concentrations.

Before starting treatment, it is necessary to rule out secondary causes of dyslipidemia and measure lipid indices periodically. If creatine kinase increases during treatment, has myositis, liver enzyme levels in the blood increase to 3 times the normal limit, the dose should be reduced or the drug is discontinued.
Use caution when using Afocical in patients with liver dysfunction, drinking a lot of alcohol. In addition, patients need to have a reasonable diet before starting the course of treatment and maintain it throughout the period of taking the drug.

Store Afocical in the original manufacturer's packaging, in a cool, clean place, avoid direct exposure to sunlight, at a temperature below 30 degrees Celsius. Keep Afocical out of reach of children and objects. rearing, avoiding the case that not knowing how to chew can cause serious unwanted effects. Afocical has a shelf life of 36 months, do not use drugs that have expired or show signs of change in color, properties, taste, no labels. Do not throw Afocical down the toilet or plumbing unless told to do so. Above is all information about Afocical drug, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Note, Afocical is a prescription drug, patients need to use the drug as prescribed by the doctor, absolutely do not self-treat at home.