Uses of Alenta 70

Alenta tablets have an ingredient of Sodium Alendronate, there are strengths of Alenta 70mg and Alenta 10mg. This article is mainly about the drug Alenta 70mg.
Ingredients Sodium Alendronate is a bisphosphonate . The drug has a strong and localized inhibitory effect on the sites of bone absorption, especially just below the osteoclasts.
Alenta 70mg is indicated for use in the following cases:
Treatment of osteoporosis in postmenopausal women, reducing the risk of hip and spine fractures; Treatment of osteoporosis in men at high risk of fracture, reducing the incidence in the spine; Prevention of the risk of osteoporosis due to long-term glucocorticoid use. Drug Alenta 70mg is contraindicated in the following cases:
People who are hypersensitive to the ingredients of the drug; Persons unable to sit upright or stand for at least 30 minutes; People with abnormalities in the esophagus (elasticity, narrowing of the esophagus) prolonging gastric emptying time; Patients with hypocalcemia ; Children under 18.

Usage: Orally. Patients should take the drug on an empty stomach, as soon as they wake up in the morning, should drink with filtered water (from 200ml or more), at least 30 minutes before breakfast, drinking or taking other drugs.
*Note when taking the drug:
Patients should supplement vitamin D and calcium if the diet is not adequate; Patients should also not chew, suck or dissolve the tablet in the mouth to avoid the risk of mouth and pharyngeal ulcers; Patients should not lie down until after the first meal of the day, at least 30 minutes after taking the medicine. Dosage: General recommendations are as follows:
Treatment of postmenopausal osteoporosis: 10mg/time/day; Treatment of osteoporosis in men: Use a dose of 10mg / time / day. *Note on dosage:
The duration of drug administration for the patient has not been determined. The need for continued treatment will be periodically assessed by the physician based on the benefits and potential risks for each patient (especially after using the drug for more than 5 years); Dosage depends on the age and condition of the individual patient, 70mg/week is recommended; No dose adjustment is required in elderly patients; No dose adjustment is required in patients with GFR >35ml/min; No dose adjustment is required in patients with hepatic impairment. Overdose: Patients taking an overdose of Alenta may experience hypocalcemia, hypophosphataemia, and some gastrointestinal symptoms (heartburn, esophagitis, digestive disorders, stomach inflammation/ulcer). . In case of overdose, the patient should be given milk or an antacid to combine with alendronate. In addition, because of the risk of esophageal irritation, do not induce vomiting, the patient should be in an upright position.
Missed dose: If you forget to take Alenta 70mg once a week, the patient should take 1 pill in the morning after remembering. Patients should not take 2 tablets in the same day but return to taking 1 tablet / week as originally planned.

When using Alenta, patients may experience some side effects such as:
Common: Headache, dizziness, dizziness, abdominal pain, indigestion, diarrhea, constipation, flatulence, difficulty swallowing, esophageal ulceration, abdominal distention, heartburn, alopecia, skin pruritus, musculoskeletal pain (sometimes very severe), asthenia, peripheral edema; Uncommon: Taste disturbance, ocular infections (scleritis, scleritis, peritonitis), nausea, vomiting, esophagitis, gastritis, esophagitis, melena , rash, erythema of the skin, acute reaction (myalgia, weakness, fever) at the start of treatment. When experiencing mild side effects of Alenta, patients should stop taking the drug and consult a doctor. In case of severe hypersensitivity, the patient should notify the doctor, immediately go to the hospital for timely treatment.

Some notes patients need to remember before and while using Alenta:
Consider other causes of osteoporosis besides age, estrogen deficiency and glucocorticoid use; Treat hypocalcaemia before initiating therapy with sodium alendronate; Other disorders that can affect mineral metabolism (vitamin D deficiency) also need to be treated. Serum calcium levels and symptoms of hypocalcemia should be monitored in these patients to ensure adequate calcium absorption and vitamin D intake, especially important in patients with Paget's disease of bone and those taking glucocorticoids. (because asymptomatic reductions in serum calcium and phosphate may occur during treatment with sodium alendronate; On the gastrointestinal system: Patients should discontinue Alenta therapy if symptoms of an esophageal reaction appear. such as: word coordination disorder, retrosternal pain, painful swallowing, new or worsening heartburn.Patients also need to be cautious when using the drug if gastrointestinal disorders are progressive; Localized osteonecrosis of the jaw: A condition commonly associated with tooth extraction, long-resolving local infections (including osteomyelitis) have been reported in patients with osteoporosis receiving alendronate.Risk factors for the development of focal osteonecrosis of the jaw include: Bisphosphonate potency, route of administration, cumulative dose; cancer patients, radiation therapy, chemotherapy, corticosteroid use steroids, smoking; people with a history of dental disease, poor oral hygiene, periodontal disease, invasive dental procedures, poor quality dentures. A dental examination for appropriate precautions should be considered before initiating oral bisphosphonates in patients with poor dental condition. During treatment, patients need to maintain good oral hygiene and have regular dental check-ups; Muscle, bone, or joint pain: Symptoms are rarely severe or loss of mobility. The onset of symptoms may be 1 day or several months after treatment. Patients will reduce symptoms after stopping taking the drug; Atypical supra-femur fracture: Mainly occurs in patients on long-term treatment for osteoporosis. During the treatment, the patient should notify the doctor if there are symptoms of thigh, hip or groin pain for examination and treatment; Skin reactions: Rarely, serious skin reactions such as toxic epidermal necrolysis or Stevens Johnson syndrome have been reported; Do not use sodium alendronate in patients with severe renal impairment with GFR <35ml/min; Mineral metabolism: Blood calcium levels and symptoms of hypocalcemia should be monitored throughout the course of drug administration. Adequate calcium and vitamin intake should be ensured (especially important in patients taking glucocorticoids); Glucocorticoid-induced osteoporosis: Patients should have their bone mineral density assessed before using a combination therapy of sodium alendronate with glucocorticoid, repeated 6-12 months later; Alenta contains lactose, so patients with galactose intolerance, glucose-galactose malabsorption or Lapp lactase deficiency should not take this medicine; Undesirable effects of the drug may affect the patient's ability to drive and use machines; Use caution when using Alenta in pregnant women and nursing mothers (as prescribed by a doctor).

Some drug interactions of Alenta 70mg include:
Estrogen: Concurrent use of 2 drugs will increase bone mass, decrease the rate of bone metabolism more; Antacids or calcium supplements interfere with the absorption of sodium alendronate, so they should be taken at least 30 minutes apart; Non-steroidal anti-inflammatory drugs when used concomitantly with Alenta increase the risk of gastrointestinal irritation. Before using Alenta 70mg, patients should inform their doctor about their medical history and any medications they are taking. Patients also need to strictly follow the doctor's instructions while taking the drug to ensure the safety and effectiveness of the drug.
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