Uses of Bazedoxifene

Bazedoxifene is used to treat osteoporosis in women going through menopause. When using the drug, users may experience some side effects. Here are a few shared information about the drug Bazedoxifene you should consult before using.

1. Uses of Bazedoxifene

Bazedoxifene is used to treat osteoporosis or vasomotor problems in postmenopausal women. For postmenopausal women, using the drug can reduce the risk of osteoporosis, especially the pelvic bones. If osteoporosis prevention is in the perimenopausal stage, you should check and consult with your doctor. Bazedoxifene is not suitable for the premenopausal group when it is necessary to prevent the risk of early osteoporosis. For women with minimal uterine damage, Bazedoxifene can be used to treat vasomotor problems during menopause.

2. Dosage and how to use Bazedoxifene


When using Bazedoxifene, you need to be careful to follow your doctor's instructions and use it at the prescribed dose. Dosage will be considered by the doctor based on the patient's situation and the actual problems and the medication the patient is taking. Due to the use of Bazedoxifene, the body needs calcium or vitamin D supplements to support calcium absorption. Calcium and Vitamin D still need to be supplemented fully and regularly even if you are taking Bazedoxifene.
Bazedoxifene tablets should be kept intact when swallowed. Each tablet will provide 20 mg of Bazedoxifene and 0.45 mg of estrogen to help improve women's health. Normally, the dose of 1 tablet/day will be used for post-menopausal women or with poor vasomotor symptoms.

3. Precautions before using Bazedoxifene


Bazedoxifene is contraindicated in people with known or at risk of liver and kidney failure. This subject may have a critical condition when the drug is excreted by the liver and kidneys, leading to an overload that causes severe functional impairment and impairment. In addition, some other cases are also contraindicated to use Bazedoxifene:
Women with uterine bleeding of unknown cause People with tumors caused by the hormone estrogen Patients with a history of or being treated for breast cancer People have cardiovascular disease, especially thromboembolism or have a history of stroke due to thrombosis The body is metabolically deficient in proteins C,S and antithrombin Pregnant or women after giving birth who are nursing young children Patients allergic to drugs cause angioedema or anaphylaxis While using Bazedoxifene, doctors and patients should pay attention to observe to be able to understand the situation to avoid unintended problems. In addition, the contraindications for interaction with estrogen should be clarified to prevent the risk of dangerous side effects for the patient.

4. Some side effects of the drug Bazedoxifene


Effects on cardiovascular health Bazedoxifene can limit the risk of vasomotor disease and osteoporosis, but it is not effective in heart arrhythmias, blood clots ... According to current studies, estrogen is not a component. suitable for the treatment of cardiovascular diseases.
According to the results of research analysis, postmenopausal women using estrogen without a doctor's supervision may be more likely to have a stroke. If you have any unusual symptoms after taking Bazedoxifene, you should inform your doctor to prevent early stroke.
For surgical patients with problems related to thrombosis should have a plan to stop the drug 4-6 weeks before surgery. After surgery, the patient should not take the drug while resting. Only when the body recovers and can walk normally will you begin to consider taking medication and under the supervision of a doctor.
Intellectual impairment There are some patients who report that they often forget quickly after taking the drug. The condition is statistically more common in people over the age of 65. However, the researchers now want to expand the analysis further into post-menopausal age to give a more general assessment of the risk of side effects. this.
Endometrial cancer Estrogen supplementation from bazedoxifene after menopause has been found to increase the risk of endometrial cancer in some women. It is possible that the body has had symptoms or has had cancer before, leading to this side effect. According to clinical research, women need to regularly monitor their body, if abnormal bleeding is detected, check early to detect early signs of endometrial cancer to help doctors prevent treatment.
Endocrine disorders disrupt metabolism Estrogen is an endogenous female hormone that maintains female physiological health. After menopause, hormone levels gradually decrease, if improperly supplemented, will lead to disorders and serious health effects. Endocrine disorders often affect the thyroid gland, increasing the concentration of triglycerides in the blood plasma. When a patient is diagnosed with pancreatitis, consider treatment to limit the danger of side effects.

5. Interactions when taking Bazedoxifene


Drug interactions can appear when the patient uses foods and drugs that affect estrogen levels. You should discuss this further with your doctor for specific advice on drugs or foods to avoid while taking Bazedoxifene.
Bazedoxifene hormonal supplements to prevent osteoporosis and vasomotor should not be self-administered. You need to consult your doctor and have a medical examination before deciding to take this medicine.

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