Uses of Ciloxane

What is Ciloxan? Ciloxan medicine has the main active ingredient is Ciprofloxacin Hydrochloride monohydrate with a concentration of 0.3% and other excipients with a sufficient amount of 5ml. The drug belongs to the group of treatment of Ear, Nose and Throat disease, namely the treatment of conjunctivitis, corneal ulcer,...
Ciloxan drug is in the form of an eye drop solution. Packing is a medicine box with 1 vial and 5ml each.
1.1. Ingredients of the drug Ciloxan The main active ingredient is Ciprofloxacin hydrochloride equivalent to Ciprofloxacin 3mg. Preservative is Benzalkonium chloride 0.006% Excipients include Sodium Acetate, Mannitol, Acetic Acid, Disodium Edetate, Hydrochloric acid and/or Sodium hydroxide (for pH adjustment), purified water. 1.2. Pharmacology of the drug Ciloxan The main active ingredient Ciprofloxacin is a multi-dose, sterilizing, synthetic antibacterial antibiotic used in ophthalmology. Systemic absorption: A systemic absorption study was performed in which Ciloxan ophthalmic solution was instilled every two hours while awake for a period of two days. After that, you apply the drops for an additional 5 days, followed by instillation every four hours while awake. The maximum plasma concentration of the active ingredient Ciprofloxacin has been reported to be less than 5 ng/ml. The average concentration is usually below 2.5 ng/ml. The effect of the drug Ciloxan: Ciloxan eye drops have the main use of antibacterial and anti-viral properties. This effect of the drug is through the pharmacological action of the active ingredient Ciprofloxacin. This is a drug belonging to the group of antibacterial drugs with quinolone structure, which inhibits the growth and development of bacteria, kills bacteria by inhibiting the enzyme DNA Gyrase - Enzyme involved in the synthesis of chromosomes. of bacteria. Broad spectrum of activity against many Gram-positive and Gram-negative bacteria, some viruses sensitive to the antibiotic Ciprofloxacin.

Ciloxan ophthalmic solution is indicated for use in cases of infections caused by susceptible strains of the specified bacteria in the following diseases:
Corneal ulcers caused by Streptococcus pneumoniae, Serratia marcescens , Staphylococcus aureus, Pseudomonas aeruginosa, Staphylococcus epidermidis, Streptococcus (group of viridans). Conjunctivitis caused by bacteria Staphylococcus epidermidis, Staphylococcus aureus, Streptococcus pneumoniae. Blepharitis is caused by infection with bacteria and viruses that are sensitive to the antibiotic Ciprofloxacin.

How to use and dose of Ciloxan drug as follows:
3.1. Dosage of Ciloxan The usual dose of Ciloxan used by a pharmacist or doctor is as follows:
Dosage for treatment of corneal ulcers
Day 1: In the first 6 hours, instill 2 drops every 15 minutes, 4 hours later 2 drops every 30 minutes. Day 2: Instill 2 drops/time/hour. Day 3 to day 14: Instill 2 drops/time, 4 hours apart between 2 times. Dosage for treatment of conjunctivitis, blepharitis
Dosage in the first 2 days: 1-2 drops/time, every 2 hours. Dosage in the following 5 days: 1-2 drops / time, between 2 doses every 4 hours. Prevention of infection during surgery
Every 15 minutes, drop the medicine once, instill 4 times within 1 hour before surgery. Note: Ciloxan dosage as above is for reference only, not every person will take the same dose as above. Therefore, patients need to go to hospitals and medical centers for doctors to examine, take medical history and prescribe drugs with appropriate doses, improve treatment effectiveness and avoid unwanted side effects. wish to happen.
3.2. How to use Ciloxan effectively Ciloxan medicine is prepared in the form of eye drops, used in the eyes. Wash hands thoroughly. Open the vial cap and avoid letting the dropper stopper come into contact with your eyes or eyelids. Put Ciloxan in the eye looking up, pull down the lower eyelid slightly, close the eye, wipe off the residue. You need to pay attention to strictly follow the instructions for using Ciloxan medication of the treating doctor during use. 3.3. Cases of drug overdose Currently, no case of overdose related to the use of drugs containing the active ingredient Ciprofloxacin has been reported when using Ciloxan eye drops. In case of overdose of Ciloxan eye drops, you can immediately wash your eyes with warm water to remove the drug. In the course of use, if the patient develops an abnormal reaction suspected of using an overdose of the drug, they should stop using it and go to a medical facility for timely treatment.

During the use of Ciloxan eye drops, the patient may experience the following undesirable effects:
Common: Burning, eye irritation, white crystals appear in the eyes. Eyes at the affected site Uncommon: Bitter taste in mouth after instillation, conjunctival congestion, edema, scabs in eyes, pruritus in eyes. Rare: Eyelid edema, increased photosensitivity, nausea, keratitis, decreased visual acuity, allergy in the area where the drug has been applied... Effects on laboratory parameters/urine deposits: Yes may transiently increase the alkaline phosphatase and transaminase indices, as well as cause obstructive jaundice, especially in those with previous liver damage; transient increase in serum urea, creatinine or bilirubin; Hyperglycemia: in special cases, crystalluria and hematuria may be present. When experiencing any serious side effects, the patient should stop taking the drug and inform the doctor to receive appropriate advice.

Specific drug interaction studies have not been conducted with Ciprofloxacin ophthalmic. However, systemic administration of several quinolones has been shown to increase serum theophylline concentrations, inhibit caffeine metabolism, and potentiate the effects of oral anticoagulants, warfarin, and its derivatives. it and associated with a transient increase in serum creatinine in subjects receiving concomitant Cyclosporine.
To avoid drug interactions, you should proactively inform your treating doctor if you are taking any other medications or treatment products. At that time, the doctor will have instructions on how to use it safely, effectively and avoid drug interactions.

During the use of Ciloxan, patients need to pay attention to the following issues:
6.1. Contraindications of the drug Ciloxan Ciloxan drug is contraindicated for the following subjects:
People with a sensitive or sensitive background or allergy to the main active ingredient Ciprofloxacin or to other ingredients of the drug. People with a history of allergy to Quinolone antibiotics. If you have any questions about subjects who do not use drugs, please contact your doctor immediately for the fastest and most accurate answer. 6.2. Note when using Ciloxan In the process of using Ciloxan, patients should pay attention to some of the following issues:
Similar to when using other antibiotic preparations, the use of Ciloxan medicine during Prolonged periods can lead to overgrowth of non-susceptible bacteria, including fungi. If superinfection occurs, appropriate treatment should be initiated. Ciloxan should be discontinued at the first appearance of skin redness or any other sign of a hypersensitivity reaction. Do not touch the tip of the dropper with your hands or any object, as this may contaminate the solution. 6.3. Use of Ciloxan in Special Populations Use of Ciloxan in Pregnancy: There are currently no adequate well-controlled studies in pregnant women. Therefore, Ciloxan ophthalmic solution should be used during pregnancy only if the potential benefit outweighs the potential risk to the fetus. Use of Ciloxan in Lactation: It is not known whether topically small Ciprofloxacin is excreted in human milk. Therefore, caution should be exercised when using Ciloxan in women who are breast-feeding. Using the drug while driving or operating machinery: As with any other eye drop, temporary blurred vision and visual disturbances can affect the reaction rate to the point of reduced ability to drive vehicles and operate machinery. The effect is even greater when Ciloxan is used with alcohol. 6.4. How to store Ciloxan Do not use Ciloxan when it has expired or shows signs of damage. Keep Ciloxan out of reach of children and pets. Store Ciloxan in a dry place at room temperature. Avoid exposing Ciloxan to direct sunlight or humid air. Above is all information about Ciloxan drug, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Ciloxan medicine to treat the disease at home, because there may be unwanted side effects on health.
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