Uses of Clarixten

Clarixten belongs to the group of anti-parasitic, anti-infective, anti-viral, anti-fungal drugs. The drug is indicated for the treatment of common bacterial infections. Let's learn about Clarixten on how to use it and what precautions to take to ensure it's safe and effective for patients.

Clarixten contains Clarithromycin 250mg and other excipients just enough for 1 tablet provided by the manufacturer. The drug is prepared in the form of film-coated tablets, packaged in a box of 2 blisters, each blister has 10 tablets.

Clarixten is indicated for the treatment of the following cases:
Skin and soft tissue infections. Inflammation of the upper respiratory tract such as sinusitis, pharyngitis, otitis media, tonsillitis. Lower respiratory tract infections such as: Acute bronchitis, chronic bronchitis, pneumonia, COPD exacerbations. Combination treatment of peptic ulcers caused by Helicobacter pylori. Kills bacteria Mycoplasma pneumoniae and Legionella causing pneumonia, diphtheria, early stage of whooping cough, opportunistic infections caused by Mycobacterium. In addition, the drug Clarixten is contraindicated in the following cases:
Patients who are allergic to the active ingredient Clarithromycin or other excipients in the composition of the drug Patients with a history of bradycardia, arrhythmia, heart disease with approx. QT prolongation, coronary insufficiency, electrolyte imbalance.

Clarixten is made in the form of film-coated tablets, so the drug is taken orally. The drug should be swallowed whole, the patient should not chew, crush or break the tablet before taking it.
Because the drug is not affected by food, it can be taken before or after a meal without reducing the extent or speed of absorption of the drug.
Below is the dosage of Clarixten:
Adults:
Dose is 250mg x 2 times daily for 7 days continuously, or 500mg of adjusted release form once daily. In severe infections this can be increased to 500mg twice daily, or 1000mg of a modified release form once daily and continued for up to 14 days. In the case of combination treatment of peptic ulcer caused by Helicobacter pylori, the usual dose is 500mg x 2 times daily, used continuously for 7 days. Patients should be used in combination with Omeprazole 40mg orally twice a day. Children over 12 years old:
Use the same dose as adults. Children under 12 years: Use this drug in the form of emulsions for pediatric patients with specific doses as follows:
The daily dose for children is 7.5mg/kg body weight, 2 times a day until the time of death. The maximum dose is 500mg. The duration of each course of treatment is 7-10 days, depending on the strain of bacteria causing the disease and how severe or mild the disease is. In the case of treatment for strep throat, it is necessary to treat it for at least 10 days. The prepared solution can be taken with or without meals and can be taken with milk. Elderly:
Use the same dose as adults. Patients with renal impairment:
No dose adjustment is necessary unless the patient has severe renal impairment (based on creatinine clearance less than 30ml/min. Adjustment should reduce the total daily dose by half. Note: This is the reference dose provided by the manufacturer. Based on the disease condition and health of each patient, the doctor can prescribe the appropriate dose.

The doctor always considers the benefit that Clarixten brings to the patient and the possible risk of side effects to prescribe the appropriate medication.
Clarixten is well tolerated, some side effects may be encountered when taking the drug, including:
Gastrointestinal disturbances, nausea, vomiting, dyspepsia, diarrhea, abdominal pain. Stomatitis, glomerulonephritis, raised nodules around the mouth. Headache, allergic reactions ranging from urticaria and mild skin rashes to anaphylaxis and, rarely, Stevens-Johnson syndrome. Taste disturbance, loss of color in the tongue. Anxiety, dizziness, insomnia, hallucinations, psychosis, nightmares, confusion. Loss of hearing. Pseudomembranous colitis, liver dysfunction, hepatitis and biliary tract infection with or without associated jaundice. Note: When patients appear side effects that are not listed in the instructions for use. Inform your doctor or medical officer immediately if you suspect any side effects of Clarixten.

When used in combination with the following drugs with Clarixten, the following interactions may occur:
Use in combination with drugs used to treat epilepsy: Clarixten inhibits the metabolism of drugs such as Carbamazepine and Phenytoin. increase their side effects. Clarixten inhibits metabolism leading to prolonged QT interval, torsades de pointes, and ventricular fibrillation. Clarixten inhibits the hepatic metabolism of theophylline and increases its plasma concentrations, leading to the risk of drug toxicity. It also reduces the absorption of Zidovudine. The use of Clarixten in patients taking Warfarin may potentiate its effects. Therefore, prothrombin time should be regularly monitored in these patients. The efficacy of Digoxin may be increased by concomitant administration of Clarixten, so serum levels of Digoxin should be monitored. There may be other interactions of Clarixten with food or other medications not listed above. Therefore, stop using this medicine and seek medical attention as soon as any unusual reactions occur.
To avoid interactions, before being prescribed Clarixten, patients should inform their doctor about all the drugs they are using, including functional foods.

Some notes when patients take Clarixten as follows:
Clarixten is excreted mainly by the liver and kidneys. Therefore, caution should be exercised when using this antibiotic in patients with impaired liver or kidney function. Prolonged and repeated use of Clarixten may lead to the development of strains of fungi or bacteria that are no longer susceptible to the drug. In case of superinfection, the patient should be instructed to stop taking the drug and start treatment according to the appropriate regimen. There is a risk of increased serum concentrations of drugs when used in combination with Clarixten that is metabolised by the cytochrome P450 system. Pregnant women: When using Clarixten, there may be potential risks to the fetus such as miscarriage, malformation,... Therefore, use this medicine only when prescribed by a doctor. Lactation: The drug is known to be excreted in breast milk, so there is a risk of harm to the nursing infant when taking the drug. In case the mother has to take this medicine for the treatment, the patient can stop breastfeeding during the treatment period. Use medication only when prescribed by your doctor.

If you forget to take your medicine, take it as soon as you remember. The drug can be taken about 1-2 hours later than the daily dose. But when it is almost time for the next dose, the missed dose should be thrown away. Patients should absolutely not make up for a double dose. When taking an overdose, patients often experience symptoms such as itching, skin allergies, nausea, vomiting, dizziness, hypotension, convulsions, shortness of breath, respiratory failure, tachycardia... In this case, the drug should be stopped immediately when detecting the above side effects and informing the treating doctor. Family members should take the patient to the hospital for timely examination and treatment. Patients should also bring the medications they have used so that the doctor can get information and handle it quickly and promptly. Hopefully, the above article has provided all the relevant information about the uses, dosage and some notes when using Clarixten. Patients should take Clarixten exactly as directed by their doctor. Note, Clarixten is a prescription drug, patients can only use this drug when prescribed by a specialist.